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Interstitial Lung Diseases

Healthcare utilisation and costs in the diagnosis and treatment of progressive-fibrosing interstitial lung diseases

Healthcare utilisation and costs in the diagnosis and treatment of progressive-fibrosing interstitial lung diseases

... chronic diseases [2 – ...of interstitial lung diseases (ILDs) that may present a progressive fibrosing phenotype, and the factors impacting healthcare ...

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Pulmonary hypertension in chronic interstitial lung diseases

Pulmonary hypertension in chronic interstitial lung diseases

... of interstitial lung diseases (ILDs), particularly in idiopathic pulmonary fibrosis and ILD associated with connective tissue ...other lung diseases, such as combined pulmonary fibrosis ...

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Personalised medicine in interstitial lung diseases

Personalised medicine in interstitial lung diseases

... ABSTRACT Interstitial lung diseases in general, and idiopathic pulmonary fibrosis in particular, are complex disorders with multiple pathogenetic pathways, various disease behaviour profiles and ...

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Pharmacological management of progressive-fibrosing interstitial lung diseases: a review of the current evidence

Pharmacological management of progressive-fibrosing interstitial lung diseases: a review of the current evidence

... with interstitial lung diseases (ILDs) are at risk of developing a progressive-fibrosing phenotype, which is associated with a deterioration in lung function and early ...nonspecific ...

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Exertional dyspnoea in interstitial lung diseases: the clinical utility of cardiopulmonary exercise testing

Exertional dyspnoea in interstitial lung diseases: the clinical utility of cardiopulmonary exercise testing

... Interstitial lung diseases (ILDs) represent a heterogeneous group of pathologies characterised by alveolar and interstitial space damage, pulmonary inflammation (usually coupled with ...

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Role of imaging in progressive-fibrosing interstitial lung diseases

Role of imaging in progressive-fibrosing interstitial lung diseases

... ABSTRACT Imaging techniques are an essential component of the diagnostic process for interstitial lung diseases (ILDs). Chest radiography is frequently the initial indicator of an ILD, and comparison ...

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Long-term macrolides in diffuse interstitial lung diseases

Long-term macrolides in diffuse interstitial lung diseases

... ABSTRACT In the present review we provide currently available evidence for the use of macrolides in the treatment of diffuse interstitial lung diseases (ILDs). Up to now, research on macrolides has ...

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Endotoxin markers in bronchoalveolar lavage fluid of patients with interstitial lung diseases

Endotoxin markers in bronchoalveolar lavage fluid of patients with interstitial lung diseases

... diffuse lung dis- ...smoking-related interstitial lung diseases (sr-ILD) (n = 11, mean age 53 ...and lung fibrosis (n = 42, mean age 62 ...of interstitial lung dis- eases ...

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Systems biology of interstitial lung diseases: integration of mRNA and microRNA expression changes

Systems biology of interstitial lung diseases: integration of mRNA and microRNA expression changes

... We have demonstrated here the power of focusing on the key regulatory components, the transcription factors and miRNAs, in order to gain insight into the networks perturbed in complex diseases such as ILDs. The ...

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Presentation, diagnosis and clinical course of the spectrum of progressive-fibrosing interstitial lung diseases

Presentation, diagnosis and clinical course of the spectrum of progressive-fibrosing interstitial lung diseases

... with interstitial lung diseases (ILDs) may develop a progressive-fibrosing ...symptoms, lung function decline, limited response to immunomodulatory therapies, decreased quality of life and, ...

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Angiogenesis in Interstitial Lung Diseases: a pathogenetic hallmark or a bystander?

Angiogenesis in Interstitial Lung Diseases: a pathogenetic hallmark or a bystander?

... 4. Pathogenetic pathways during aberrant angiogenesis Several transcription factors play instrumental role in pro- moting angiogenesis and sensing the environmental cues that drive this process. Strieter et al. [22] ...

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The epidemiology of idiopathic pulmonary fibrosis and interstitial lung diseases at risk of a progressive-fibrosing phenotype

The epidemiology of idiopathic pulmonary fibrosis and interstitial lung diseases at risk of a progressive-fibrosing phenotype

... Interstitial lung diseases (ILDs) are rare diseases that share a number of common clinical and pathophysiological features, but also demonstrate a diverse aetiology and prognosis ...

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Transbronchial Lung Cryobiopsy in the Diagnosis of Interstitial Lung Diseases  Looking at the Holy Grail or Another Misleading Diagnostic Approach?

Transbronchial Lung Cryobiopsy in the Diagnosis of Interstitial Lung Diseases Looking at the Holy Grail or Another Misleading Diagnostic Approach?

... Interstitial lung diseases (ILD’s) are a group of heterogenous chronic, fero- ciously progressive lung ...dismal diseases is a vivid challenge for the ...these diseases or a ...

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Non-invasive mechanical ventilation in patients with diffuse interstitial lung diseases

Non-invasive mechanical ventilation in patients with diffuse interstitial lung diseases

... tissue diseases; ECMO: Extra-corporeal membrane oxygenation; ETI: Endotracheal intubation; HDU: High dependency units; HP: Hypersensitivity pneumonitis; HRCT: High resolution CT; ICU: Intensive care unit; DILD: ...

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Spectrum of HRCT findings in interstitial lung diseases and their correlation with mediastinal lymphadenopathy

Spectrum of HRCT findings in interstitial lung diseases and their correlation with mediastinal lymphadenopathy

... Background: Interstitial lung disease (ILD) represents a heterogeneous non-infectious group of acute and chronic diseases affecting the lung ...

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Pulmonary arterial wall disease in COPD and interstitial lung diseases candidates for lung transplantation

Pulmonary arterial wall disease in COPD and interstitial lung diseases candidates for lung transplantation

... prevalent, including lesions Grade 3 (Heath & Edwards) even in patients without PH [12]. The analysis of the United Network for Organ Sharing database showed that an increase in the mean pulmonary arterial pressure ...

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Treatment of progressive fibrosing interstitial lung diseases: a milestone in the management of interstitial lung diseases

Treatment of progressive fibrosing interstitial lung diseases: a milestone in the management of interstitial lung diseases

... Support of this concept has emanated from in vitro studies and animal models for both nintedanib and pirfenidone. Nintedanib, an intracellular inhibitor of tyrosine kinases [27, 28], has shown antifibrotic, ...

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Lung Pattern Classification for Interstitial Lung Diseases Using a Deep Convolutional Neural Network

Lung Pattern Classification for Interstitial Lung Diseases Using a Deep Convolutional Neural Network

... Software development for the detection of pulmonary nodules can be explained by using Data Flow Diagrams (DFD) as in Figure 2. Data Flow Diagrams (DFD) level 1 illustrates the flow of information and transformation ...

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Childhood Interstitial Lung Diseases: An 18-year Retrospective Analysis

Childhood Interstitial Lung Diseases: An 18-year Retrospective Analysis

... the lung, such as the ...without lung bi- opsy. In our cohort, 2 cases originally evaluated by lung biopsy were later found to have genetic etiologies (1 SFTPC mutation and 1 with compound ...

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Lung Pattern Classification for Interstitial Lung Diseases Using an Artificial Neural Network

Lung Pattern Classification for Interstitial Lung Diseases Using an Artificial Neural Network

... ABSTRACT: Lung is the organ that allows us to breathe and lung disease are the disorders that affect the ...the lung diseases by effective feature extraction through Dual-Tree Complex Wavelet ...

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