lymphatic endothelial cell
Macrophages define dermal lymphatic vessel calibre during development by regulating lymphatic endothelial cell proliferation
... myeloid cell-derived VEGFA has a profound effect on tumour angiogenesis even in the absence of a detectable change in the amount of total VEGFA expressed in the tumour microenvironment (Stockmann et ...embryonic ...
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Notch1 functions as a negative regulator of lymphatic endothelial cell differentiation in the venous endothelium
... mice, lymphatic vascular development initiates around embryonic day (E) ...of endothelial cells (ECs) of the cardinal vein (CV) (Oliver et ...of lymphatic endothelial cell (LEC) ...
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Mouse lymphatic endothelial cell targeted probes: anti-LYVE-1 antibody-based magnetic nanoparticles
... intratumoral lymphatic vessels, the occurrence and development of lymphatic vessels cannot be dynamically ...tumor lymphatic vessels, and finally flow back into the venous system, so that the intra- ...
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Lymphatic endothelial cell immunohistochemical markers for evaluation of the intestinal lymphatic vasculature in dogs with chronic inflammatory enteropathy
... dogs. Of these dogs, 3 were euthanized as a consequence of their dis- ease, 1 was euthanized because of unrelated disease, and 2 were alive at the time of publication. Of the 3 dogs that were euthanized because of their ...
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Sunitinib inhibits lymphatic endothelial cell functions and lymph node metastasis in a breast cancer model through inhibition of vascular endothelial growth factor receptor 3
... in lymphatic vascular for- mation, and VEGFR-3 inhibition by antibody has been shown to disrupt the cellular functions of LECs and adult lymphangiogenesis ...of lymphatic vessels is not well ...in ...
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Endothelial cell plasticity: how to become and remain a lymphatic endothelial cell
... mutant lymphatic vessels was also partially reprogrammed as they acquired some features typical of the blood vasculature and even became filled with ...Prox1-dependent, cell-autonomous ...differentiated ...
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Novel Identification of LYVE 1 Positive Macrophages in Rheumatoid Synovial Tissue
... Introduction The aim of the current study was to examine if macrophages expressing the lymphatic endothelial cell specific hyaluronan receptor LYVE-1 LYVE-1 positive macrophages existed [r] ...
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Rasip1 controls lymphatic vessel lumen maintenance by regulating endothelial cell junctions
... the lymphatic vasculature leads to congenital or inherited disorders, including ...the lymphatic vasculature was not appreciated in full detail until recently, as emerging studies unraveled additional and ...
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Slit2N and Robo4 regulate lymphangiogenesis through the VEGF-C/VEGFR-3 pathway
... vascular endothelial cell ...microvascular endothelial cells (HMVEC) and human umbilical vein endothelial cells (HUVEC); they pro- mote vascular stability and inhibit hyperpermeability in a ...
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Cytotrophoblast induction of arterial apoptosis and lymphangiogenesis in an in vivo model of human placentation
... the endothelial cells and smooth muscle walls of the ...stimulated lymphatic endothelial cell migration via the actions of VEGF family members, FGF, and ...since lymphatic vessels were ...
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Original Article Lymphangigenesis in human epithelial ovarian cancer is related to the formation of ascites
... for lymphatic endothelial cell marker D2-40 and cell proliferation-associated marker Ki-67, lymphatic vessel density (LVD), lymphatic vessel proliferation (LVP), and ...
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RASSF8 downregulation promotes lymphangiogenesis and metastasis in esophageal squamous cell carcinoma
... increased cell invasion ability and promoted lymphatic endothelial cell tube formation and migration; RASSF8 overexpression had the opposite ...
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Migration of lymphatic endothelial cells and lymphatic vascular development in the craniofacial region of embryonic mice
... 1. Lymphatic endothelial cell differentiation in the cardinal vein and lymphatic development in the ...(M–R). Cell nuclei were stained with DAPI ...
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Lymphatic endothelial cells attenuate inflammation via suppression of dendritic cell maturation
... Vascular endothelial growth factor-C (VEGF-C)-induced lymphangiogenesis and increased tissue drainage have been reported to inhibit acute and chronic inflammation, and an activated lymphatic endothelium ...
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Everolimus for Primary Intestinal Lymphangiectasia With Protein-Losing Enteropathy
... To the best of our knowledge, this is the first report of everolimus use in a patient with PIL. The clinical response to mTOR inhibitors such as sirolimus and everolimus may be related to inhibition of lymphatic ...
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Emerging biology of sphingosine 1 phosphate: its role in pathogenesis and therapy
... in vivo (42). A synthetic S1P 1 signaling pathway was genetically engineered in these mice so that a transcription factor is released from activated S1P 1 to turn on a GFP reporter gene. In embryos from these reporter ...
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IL 6 and IL 10 are associated with good prognosis in early stage invasive breast cancer patients
... cancer cell line ...HT-29 cell line was not significantly changed following treatment with IL-10 [36], however, in murine models of breast and melanoma cancers IL-10 showed anti-metastatic effects ...BC ...
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Lymphatic Tissue Engineering and Regeneration
... the lymphatic system, almost every major organ including the heart, lungs, liver, kidneys, nervous system, bone, and cartilage have been targeted with tissue engineering efforts to develop functional replace- ment ...
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PTRF/Cavin-1 decreases prostate cancer angiogenesis and lymphangiogenesis
... cancer cell versus stromal cell specificity in expression pattern and functionality [21;29- ...and cell lines has begun to unveil a potential tumour-suppressor role for PTRF, which was reported to be ...
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A truncation allele in vascular endothelial growth factor c reveals distinct modes of signaling during lymphatic and vascular development
... of lymphatic vessel development (Hogan et ...for endothelial tip cell migration during angiogenesis, consistent with the proposed role of its receptor flt4 (Siekmann et ...an endothelial ...
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