Major histocompatibility
Major Histocompatibility Complex Differentiation in Sacramento River Chinook Salmon
... The chinook salmon of the Sacramento River, California, have been reduced to a fraction of their former abundance because of human impact and use of the river system. Here we examine the genetic variation at a ...
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Conditional analysis of the major histocompatibility complex in rheumatoid arthritis
... We performed a whole-genome association study of rheumatoid arthritis susceptibility using Illumina 550k single-nucleotide polymorphism (SNP) genotypes of 868 cases and 1194 controls from the North American Rheumatoid ...
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Molecular analysis of major histocompatibility complex alleles associated with the lupus anticoagulant
... thromboses. Major histocompatibility complex (MHC) class II alleles (HLA-DR and DQ) were determined by restriction fragment length polymorphisms (RFLP) in 20 patients with APA ...
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The role of major histocompatibility complex molecules in luteal function
... delineated, considerable effort in the late 1970s and 1980s was spent characterizing the morphological and functional characteristics of the large and small steroidog- enic cells. This was followed in the 1990s by ...
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Development and Use of Multimeric Major Histocompatibility Complex Molecules
... Enumeration and analysis of antigen-specific T cells play a central role in cellular immunology. While many methodolo- gies have been established for the analysis of humoral re- sponses, until recently the direct ...
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Extended major histocompatibility complex haplotypes in patients with gluten sensitive enteropathy
... heterozygotes for HLA-DR3 and DR7 was consistent with recessive inheritance of the major histocompatibility complex-linked susceptibility gene for gluten-sensitive enteropathy. On the other hand, by odds ...
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Extended major histocompatibility complex haplotypes in type I diabetes mellitus
... We have studied major histocompatibility complex markers in Caucasian patients with type I diabetes mellitus and their families. The frequencies of extended haplotypes that were composed of specific HLA-B, ...
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Major Histocompatibility Complex Variation in the Endangered Przewalski’s Horse
... HE major histocompatibility complex (MHC) is a in which specific MHC haplotypes or genotypes provide fundamental part of the immune system in nearly resistance to parasites (Briles et ...
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The Implications of Intergenic Polymorphism for Major Histocompatibility Complex Evolution
... the major histocompatibility com- ences in underlying mutational mechanisms and selec- plex (Mhc) loci, the most polymorphic loci in humans tive influences that may promote or reduce polymor- (Klein et ...
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The Major Histocompatibility Complex Class I Genes of Zebrafish.
... the major histocompatibility complex (MHC) were named after the discovery that they encode the primary antigens responsible for determining transplant compatibility (Klein 2001), MHC molecules also play a ...
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Multiple sclerosis: major histocompatibility complexity and antigen presentation
... 27. Yeo TW, De Jager PL, Gregory SG, Barcellos LF, Walton A, Goris A, Fenoglio C, Ban M, Taylor CJ, Goodman RS, Walsh E, Wolfish CS, Horton R, Traherne J, Beck S, Trowsdale J, Caillier SJ, Ivinson AJ, Green T, Pobywajlo ...
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Alloreactivity and Association of Human Natural Killer Cells with the Major Histocompatibility Complex
... All NK cells potentially lytic for autologous cells but not expressing self-major histocompatibility complex (MHC)-reactive receptors could be eliminated by a negative selection mechanism during ontogeny. ...
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Histocompatibility alloantigens in psoriasis and psoriatic arthritis Evidence for the influence of multiple genes in the major histocompatibility complex
... The frequency of HLA-A, B, and Cw antigens as well as the antigens expressed preferentially on B cells and monocytes (DRw and Ia-like) was examined in a normal population and two related disease populations, psoriasis ...
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The chromosomal order of genes controlling the major histocompatibility complex, properdin factor B, and deficiency of the second component of complement
... INTRODUCTION Evidence has been presented for the linkage of the HLA histocompatibility genes HLA-A, B, C, D,1 collectively referred to as the major histocompatibility complex MHC, to the[r] ...
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An ontology for major histocompatibility restriction
... Major histocompatibility complex (MHC) proteins play a central role in the adaptive immune system. First discovered due to their role in transplant rejection, MHC molecules are encoded by a large family of ...
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Transcriptional and posttranscriptional regulation of class I major histocompatibility complex genes following transformation with human adenoviruses.
... Tumorigenicity of hamster and mouse cells transformed by adenovirus type 2 and 5 is not influenced by the level of class I major histocompatibility antigens expressed on the cells.. The [r] ...
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The High-Frequency Major Histocompatibility Complex Class I Allele Mamu-B*17 Is Associated with Control of Simian Immunodeficiency Virus SIVmac239 Replication
... 2003. Major histocompatibility complex class I alleles associated with slow simian immunodeficiency virus disease progression bind epitopes recognized by dominant acute-phase cy- totoxic-T-lymphocyte ...
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George Snell's First Foray Into the Unexplored Territory of the Major Histocompatibility Complex
... Gorer, P. A., and Z. B. Mikulska, 1954 The antibody response to Schierman, L., and A. W. Nordskog, 1961 Relationship of blood tumor inoculation: improved methods of antibody detection. type to histocompatibility ...
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Characterization of the major histocompatibility complex locus association with Behçet’s disease in Iran
... independent associations of other HLA alleles (for ex- ample, HLA-A*26, HLA-Cw*1602) and of other SNPs or genes located in the MHC locus (for example, PSORS1C1 ) [3-7]. However, these reports have also been inconsistent, ...
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Replication Timing Analysis of the Major Histocompatibility Complex on Human Chromosome 6
... The pattern of replication at a human telomeric region (16pl3.3): its relationship to chromosome structure and gene expression. Temporal order of DNA replication in the H[r] ...
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