major histocompatibility complex-II
Diminished expression of major histocompatibility complex facilitates the use of human induced pluripotent stem cells in monkey
... It was also worth to mention that, although undifferentiated iPSCs did not express CIITA, B2M −/− and CIITA − / − were more resistant to immune attack and less stimulatory to immune cells than B2M −/− single knockout. ...
14
Herpesvirus Interference with Major Histocompatibility Complex Class II-Restricted T-Cell Activation
... from major histocompatibility complex (MHC) class I-restricted cytotoxic T ...class II-restricted im- mune responses; in the following sections, we will therefore discuss recent developments ...
8
Regulation of major histocompatibility complex class II gene expression in trophoblast cells
... in choriocarcinoma cells that could repress CIITA and MHC class II expression when transfected into either HeLa cells or CH27 mouse B cells. However, the precise mecha- nism by which this utRNA may suppress CIITA ...
8
Theiler's virus persistence and demyelination in major histocompatibility complex class II-deficient mice.
... class II-de- ficient mice have also been reported for influenza virus but not Sendai virus infection (15, ...class II glycoproteins. Class II MHC and CD4 1 T cells may be functioning specif- ically ...
9
Impairment of monocytic function during Trypanosoma cruzi infection.
... Finally, infected clone 53 showed a decreased ability to present antigen to major histocompatibility complex-matched T cells, which may relate to the absence of Class II antigens or to a[r] ...
7
Genomic organisation and transcript identification in the class II region of the human major histocompatibility complex
... class II molecules play an important role in determining the specificity of an individuals immune response is through the selection of the T cell repertoire during ...
236
Original Article Design of a ProDer f1 vaccine delivered by the MHC class II pathway of antigen presentation and analysis of the effectiveness for specific immunotherapy
... the major histocompatibility complex (MHC) class II pathway, invariant chain (Ii)-seg- ment hybrids as vaccine basis to explore the efficacy of Der f 1 hybrid vaccine by virtue of ...
9
Cytotoxic T-Lymphocyte Precursor Frequencies in BALB/c Mice after Acute Respiratory Syncytial Virus (RSV) Infection or Immunization with a Formalin-Inactivated RSV Vaccine
... study, major histocompatibility complex (MHC) class I- and II-restricted, RSV-specific cytotoxic T-lymphocyte precursor (CTLp) frequencies were determined in bronchoalveolar lavage (BAL) ...
5
CD200 fusion protein decreases microglial activation in the hippocampus of aged rats
... including major histocompatibility complex Class II (MHCII) and CD40 mRNA, as well as MHCII immunoreactivity, were increased in hippocampus of aged, compared with young, rats and that these ...
23
A defect in the regulation of major histocompatibility complex class II gene expression in human HLA DR negative lymphocytes from patients with combined immunodeficiency syndrome
... Patients with an autosomal recessive combined immunodeficiency are characterized by an HLA negative phenotype of activated T and B lymphocytes. To determine the molecular basis of this syndrome we have studied the ...
6
The Major Histocompatibility Complex in Song Sparrows: Immunity, Signals, and Mate Choice
... Further research has identified MHC-mediated mating in other jawed vertebrates (Ruff et al. 2012). In fish, MHC-disassortative mate preference has been documented in, for example, Atlantic salmon (Landry et al. 2001; ...
187
Phenotypic changes in Langerhans' cells after infection with arboviruses: a role in the immune response to epidermally acquired viral infection?
... of major histocompatibility complex class I and II antigens (4, 22, 25) and the accessory and costimulatory molecules intra- cellular adhesion molecule-1–CD54, CD11a, CD18 (6, 21), and ...
6
Impact of Endogenous Intronic Retroviruses on Major Histocompatibility Complex Class II Diversity and Stability
... Several HERV structures have been mapped in the MHC class II region of different primate species, mainly within the introns of DRB genes (1, 2, 52, 58, 62). For example, intron 5 of some functionally active ...
11
Gains and Losses of HLA Class II (DR) and CD4 in Atypical Hyperplasia, Carcinoma in situ and Infiltrating Ductal Carcinoma of the Breast
... of major histocompatibility complex (MHC) class II (HLA-DR) on atypical and malignant primary mammary epithelial cells, as well as the magnitude of the stromal T lymphocytes (T4 subset) at the ...
6
T-cell recognition in experimental autoimmune thyroiditis
... four major hormonogenic sites in Tg, we demonstrated that both CH9 and ADA2 recognize an epitope containing the T4 at position 2553 in human ...by major histocompatibility complex class ...
203
Coevolution of the major histocompatibility complex and the t-complex in the mouse. II. Modification of response to sharing of histocompatibility antigens.
... For greater numbers of antigens associated with the +-haplotype than the t-haplotype (a > b), increased expression of incompatibility in +/t mothers promotes the pr[r] ...
9
<p>Major histocompatibility complex class II molecule in non-small cell lung cancer diagnosis, prognosis and treatment</p>
... class II also has been studied in ...class II had been ...class II could be induced by IFN- γ in TKB-3 and TKB-4 cell lines and the induced MHC class II expressed on cell surface instead of ...
8
Dynamics of major histocompatibility complex class II-positive cells in the postischemic brain - influence of levodopa treatment
... MHC II: major histocompatibility complex class II; tMCAO: transient Middle cerebral artery occlusion; FACS: fluorescence-activated cell sorting; HBSS: Hank ’ s balanced salt solution; ...
12
Kaposi's Sarcoma-Associated Herpesvirus Viral Interferon Regulatory Factor 3 Inhibits Gamma Interferon and Major Histocompatibility Complex Class II Expression
... class II. (A) Low surface expression of MHC II in PEL cells compared to KSHV-negative B cell ...MHC II transcripts upon vIRF-3 ...MHC II (HLA-DRA/B, -DPA/B, and -DQA/B) mRNA was analyzed by ...
8
Clinical, immunological and genetic features in eleven Algerian patients with major histocompatibility complex class II expression deficiency
... MHC II regula- tory genes, thus defining four complementation groups: MHC2A for group A, RFXANK for group B, RFX5 for group C and RFXAP for group D ...class II deficiency ...
5