major histocompatibility complex (MHC)
Diverse Peptide Presentation of Rhesus Macaque Major Histocompatibility Complex Class I Mamu-A*02 Revealed by Two Peptide Complex Structures and Insights into Immune Escape of Simian Immunodeficiency Virus
... Major histocompatibility complex class I (MHC I)-restricted CD8 ⴙ T-cell responses play a pivotal role in anti-human immunodeficiency virus (HIV) immunity and the control of ...in complex ...
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Conditional analysis of the major histocompatibility complex in rheumatoid arthritis
... We performed a whole-genome association study of rheumatoid arthritis susceptibility using Illumina 550k single-nucleotide polymorphism (SNP) genotypes of 868 cases and 1194 controls from the North American Rheumatoid ...
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The role of major histocompatibility complex molecules in luteal function
... delineated, considerable effort in the late 1970s and 1980s was spent characterizing the morphological and functional characteristics of the large and small steroidog- enic cells. This was followed in the 1990s by ...
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Development and Use of Multimeric Major Histocompatibility Complex Molecules
... Enumeration and analysis of antigen-specific T cells play a central role in cellular immunology. While many methodolo- gies have been established for the analysis of humoral re- sponses, until recently the direct ...
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Molecular analysis of major histocompatibility complex alleles associated with the lupus anticoagulant
... thromboses. Major histocompatibility complex (MHC) class II alleles (HLA-DR and DQ) were determined by restriction fragment length polymorphisms (RFLP) in 20 patients with APA ...
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Extended major histocompatibility complex haplotypes in type I diabetes mellitus
... We have studied major histocompatibility complex markers in Caucasian patients with type I diabetes mellitus and their families. The frequencies of extended haplotypes that were composed of specific ...
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Major Histocompatibility Complex Variation in the Endangered Przewalski’s Horse
... HE major histocompatibility complex (MHC) is a in which specific MHC haplotypes or genotypes provide fundamental part of the immune system in nearly resistance to parasites (Briles et ...
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The Major Histocompatibility Complex Class I Genes of Zebrafish.
... the major histocompatibility complex (MHC) were named after the discovery that they encode the primary antigens responsible for determining transplant compatibility (Klein 2001), MHC molecules also ...
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The Implications of Intergenic Polymorphism for Major Histocompatibility Complex Evolution
... plex class I genes. Proc. Natl. Acad. Sci. USA 91: 6259–6263. Klein, J., C. O’hUigin, M. Kasahara, V. Vincek, D. Klein et al., 1991 Bauer, S., V. Groh, J. Wu, A. Steinle, J. H. Phillips et al., 1999 Frozen haplotypes in ...
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Alloreactivity and Association of Human Natural Killer Cells with the Major Histocompatibility Complex
... All NK cells potentially lytic for autologous cells but not expressing self-major histocompatibility complex (MHC)-reactive receptors could be eliminated by a negative selection mechanism during ...
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The chromosomal order of genes controlling the major histocompatibility complex, properdin factor B, and deficiency of the second component of complement
... INTRODUCTION Evidence has been presented for the linkage of the HLA histocompatibility genes HLA-A, B, C, D,1 collectively referred to as the major histocompatibility complex MHC, to the[r] ...
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Major Histocompatibility Complex Differentiation in Sacramento River Chinook Salmon
... M OLECULAR markers have been used to study son 1987; Hughes and Nei 1988; Hedrick et al. 1991; population structure and variation since the ad- Markow et al. 1993; Black and Hedrick 1997). Models vent of allozyme ...
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Extended major histocompatibility complex haplotypes in patients with gluten sensitive enteropathy
... heterozygotes for HLA-DR3 and DR7 was consistent with recessive inheritance of the major histocompatibility complex-linked susceptibility gene for gluten-sensitive enteropathy. On the other hand, by ...
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The High-Frequency Major Histocompatibility Complex Class I Allele Mamu-B*17 Is Associated with Control of Simian Immunodeficiency Virus SIVmac239 Replication
... 2003. Major histocompatibility complex class I alleles associated with slow simian immunodeficiency virus disease progression bind epitopes recognized by dominant acute-phase cy- totoxic-T-lymphocyte ...
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Histocompatibility alloantigens in psoriasis and psoriatic arthritis Evidence for the influence of multiple genes in the major histocompatibility complex
... The frequency of HLA-A, B, and Cw antigens as well as the antigens expressed preferentially on B cells and monocytes (DRw and Ia-like) was examined in a normal population and two related disease populations, psoriasis ...
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A Noncanonical mu-1A-Binding Motif in the N Terminus of HIV-1 Nef Determines Its Ability To Downregulate Major Histocompatibility Complex Class I in T Lymphocytes
... The results of the computer simulation strongly suggest that the tripartite WVM motif contributes to the interaction of Nef with mu-1A. We further analyzed the intracellular localization in order to ascertain results ...
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Characterization of the major histocompatibility complex locus association with Behçet’s disease in Iran
... independent associations of other HLA alleles (for ex- ample, HLA-A*26, HLA-Cw*1602) and of other SNPs or genes located in the MHC locus (for example, PSORS1C1 ) [3-7]. However, these reports have also been inconsistent, ...
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The Major Histocompatibility Complex in Song Sparrows: Immunity, Signals, and Mate Choice
... Further research has identified MHC-mediated mating in other jawed vertebrates (Ruff et al. 2012). In fish, MHC-disassortative mate preference has been documented in, for example, Atlantic salmon (Landry et al. 2001; ...
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Major Histocompatibility Complex (MHC) Genes and Disease Resistance in Fish
... [148,152] available at the chromosome and linkage group levels (e.g. [153,154]), and for which the locations of the classical MHC class I and II loci are known; for rainbow trout, the Onmy-IA, Onmy- IB and classical MHC ...
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Diminished expression of major histocompatibility complex facilitates the use of human induced pluripotent stem cells in monkey
... It was also worth to mention that, although undifferentiated iPSCs did not express CIITA, B2M −/− and CIITA − / − were more resistant to immune attack and less stimulatory to immune cells than B2M −/− single knockout. ...
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