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Male germ cells

Cycling to and from a stem cell niche: the temporal and spatial odyssey of mitotic male germ cells

Cycling to and from a stem cell niche: the temporal and spatial odyssey of mitotic male germ cells

... of male germ cells, as gonocytes that remain in the lumen after P5 undergo apoptosis (Tres and Kierszenbaum, ...of cells with detectable pseudopods available for motility (Orth et ...neonatal ...

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Expression and epigenomic landscape of the sex chromosomes in mouse post-meiotic male germ cells

Expression and epigenomic landscape of the sex chromosomes in mouse post-meiotic male germ cells

... Results: To determine the transcriptional and chromatin state of the sex chromosomes after meiosis, we re-analyzed ten ChIP-Seq datasets performed on mouse round spermatids and four RNA-seq datasets from male ...

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MicroRNAs control mRNA fate by compartmentalization based on 3′ UTR length in male germ cells

MicroRNAs control mRNA fate by compartmentalization based on 3′ UTR length in male germ cells

... developing male germ cells cannot be cultured for an extended period of time, it is not feasible to re- capitulate all the events in an in vitro ...cKO cells provided us with an opportunity to ...

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Distinct and Cooperative Roles of amh and dmrt1 in Self-Renewal and Differentiation of Male Germ Cells in Zebrafish

Distinct and Cooperative Roles of amh and dmrt1 in Self-Renewal and Differentiation of Male Germ Cells in Zebrafish

... in male reproductive biology and depends on precise balance between self- renewal and differentiation of male germ ...in male germ cell development by generating their mutants with ...

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From testis to teratomas: a brief history of male germ cells in mammals

From testis to teratomas: a brief history of male germ cells in mammals

... The male genitalia were called “testes” probably from the Latin word “testis “ that origi- nally meant “witnesses”, because they provide evidence of ...of male germ cells and established the ...

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Comprehensive analysis of histone post-translational modifications in mouse and human male germ cells

Comprehensive analysis of histone post-translational modifications in mouse and human male germ cells

... male germ cells using antibody-based approaches, and recent studies have utilized mass spectrometry to iden- tify histone PTMs in mature mouse sperm ...immature male germ cells, ...

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Differentiation of mouse primordial germ cells into female or male germ cells

Differentiation of mouse primordial germ cells into female or male germ cells

... ectopic germ cells in the mesonephroi or adrenal cortex (Zamboni and Upadhyay, 1983; Francavilla and Zamboni, 1985) suggested that both male and female PGCs show cell-autonomous entry into meiosis if ...

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Regulation of mitosis meiosis transition by the ubiquitin ligase β TrCP in male germ cells

Regulation of mitosis meiosis transition by the ubiquitin ligase β TrCP in male germ cells

... contained germ cells with pyknotic nuclei, indicative of apoptosis, at this developmental stage ...pyknotic cells were observed at the center of tubules, not at the periphery where spermatogonia ...

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MicroRNAs 221 and 222 regulate the undifferentiated state in mammalian male germ cells

MicroRNAs 221 and 222 regulate the undifferentiated state in mammalian male germ cells

... Testes from adult mice were fixed in 4% PFA, embedded in paraffin and processed for in situ hybridization (ISH) as described previously (Nuovo et al., 2009). Briefly, cross-sections (5 μm) were adhered to glass slides, ...

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Ultrastructural localization and distribution of Nardilysin in mammalian male germ cells

Ultrastructural localization and distribution of Nardilysin in mammalian male germ cells

... the cells as a precursor or native form at this level, rendering it undetectable, and then the mature form can be present in the cytoplasm, more or less coupled with ...haploid germ cell nucleus has ter- ...

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X-IRRADIATION OF THE DEVELOPING MALE GERM CELLS OF TRIBOLIUM CONFUSUM

X-IRRADIATION OF THE DEVELOPING MALE GERM CELLS OF TRIBOLIUM CONFUSUM

... Following irradiation, each male was placed in a five gram vial with a single female for two days, then transferred to a second female for another two days and this was repeated un[r] ...

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To Break or Not To Break: Sex Chromosome Hemizygosity During Meiosis in Caenorhabditis

To Break or Not To Break: Sex Chromosome Hemizygosity During Meiosis in Caenorhabditis

... brenneri male germ cells is sequestered at the nuclear periphery where we propose SPO-11 and associ- ated proteins do not have ...meiotic cells where recombina- tion is actively engaged vs. ...

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Wnt Signaling in Sexual Dimorphism

Wnt Signaling in Sexual Dimorphism

... in male gonads is to induce the germ cells to re-enter the cell cycle and begin dividing ...the germ cells in female embryos do not divide until much later in ...female germ ...

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The polyubiquitin gene Ubi p63E is essential for male meiotic cell cycle progression and germ cell differentiation in Drosophila

The polyubiquitin gene Ubi p63E is essential for male meiotic cell cycle progression and germ cell differentiation in Drosophila

... meiotic cells (Okazaki et ...in cells entering meiosis in the yeast ubi4 ...are male and female infertile (Ryu et ...mutant male germ cells arrest in meiotic prophase, resembling ...

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Cancer/testis antigens and gametogenesis: a review and "brain-storming" session

Cancer/testis antigens and gametogenesis: a review and "brain-storming" session

... By initial definition, expression of genes coding for CT antigens should be restricted in normal tissues to male germ cells in the testis and to malignancies of various his- tological types. However, ...

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Endogenous Nodal signaling regulates germ cell potency during mammalian testis development

Endogenous Nodal signaling regulates germ cell potency during mammalian testis development

... somatic cells of the testis, triggers male germ cells to upregulate Cripto expression around ...after germ cell colonization of the developing testis (supplementary material ...XY ...

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Spermiogenesis and Male Fertility Require the Function of Suppressor of Hairy-Wing in Somatic Cyst Cells of Drosophila

Spermiogenesis and Male Fertility Require the Function of Suppressor of Hairy-Wing in Somatic Cyst Cells of Drosophila

... female germ cells begin differentiation in late larval develop- ment (Gilboa and Lehmann 2004; Song et ...2007), male germ cells begin these processes at the end of embryogenesis (Le ...

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The control of sexual identity in the Drosophila germline

The control of sexual identity in the Drosophila germline

... between male and female GSCs, including how they interact with the niche, the signaling pathways that are active in the niche, and the close interaction between GSCs and somatic stem cells in the niche ...

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Genomic imprinting and assisted reproduction

Genomic imprinting and assisted reproduction

... in male germ cells, it seems that the paternal imprints are well estab- lished in the mature, meiotic stages of ...sperm cells at different developmental stages at the 15q11–13 imprinted ...

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SirT1 is required in the male germ cell for differentiation and fecundity in mice

SirT1 is required in the male germ cell for differentiation and fecundity in mice

... in male humans (Ford et ...of male germ cell SirT1 KO ...wild-type male mice to sire progeny with age, and this cessation occurred significantly earlier in mice lacking SirT1 in male ...

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