Meglumine antimoniate
Long term follow up of dogs with leishmaniosis treated with meglumine antimoniate plus allopurinol versus miltefosine plus allopurinol
... of meglumine antimoniate plus allopurinol seem better than miltefosine plus allopurinol for treating leish- maniosis in dogs, because during the follow-up we ob- served a decrease in the incidence of ...
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Combined therapy with adipose tissue-derived mesenchymal stromal cells and meglumine antimoniate controls lesion development and parasite load in murine cutaneous leishmaniasis caused by Leishmania amazonensis
... with meglumine antimoniate (a pentavalent antimonial commonly used for the treatment of leishmaniasis) to treat the infected ...then meglumine antimoniate was combined with MSCs from the most ...
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Comparison between Combination Therapy of Oral Terbinafine and Cryotherapy versus Systemic Meglumine Antimoniate and Cryotherapy in Cutaneous Leishmaniasis: A Randomized Clinical Trial.
... In our analysis, no response to treatment was defined if the size of a lesion decreased less than 25%, partial treatment if decreased between 25% and 75%, and complete treatmen[r] ...
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Evaluation of Correlation between the in Vitro Susceptibility of Field Isolates of Leishmania major and Clinical Outcomes of Meglumine Antimoniate Therapy in Fars Province, Iran
... The in vitro intracellular susceptibility assay The efficacy of meglumine antimonite of filed isolates was conducted on the mouse macrophage cell line (J774) as previously de- scribed (Faraut-Gambarelli et al. ...
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Double blind, randomized controlled trial, to evaluate the effectiveness of a controlled nitric oxide releasing patch versus meglumine antimoniate in the treatment of cutaneous leishmaniasis [NCT00317629]
... urethane as the fourth and final one. Upon hydration, this Nitric Oxide Releasing Patch (NOP) produces a stable release of 3.5 µmol of NO during 12 hrs [41,44,45]. In a pilot study, developed in Landazuri, Santander, ...
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Vol 24, No 2 (2014)
... include meglumine antimoniate and ...of meglumine antimoniate has not been determined yet; but the evidence for inhibition of glycolysis in the parasite at the phosphofructokinase reaction has ...
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A Randomized Trial to Compare Topical MJ1 with Routine Care for the Treatment of Cutaneous Leishmaniasis
... of meglumine antimoniate alone in the treatment of lesions of CL due to ...to meglumine antimoniate was relatively low and was not effective because of their adverse effects, high cost, and ...
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Vol 24, No 2 (2014)
... given meglumine antimoniate 20 mg/kg/day/intramuscular till clinical resolution or for 28 days ...intramuscular meglumine antimoniate 10mg/kg/day along with allopurinol 20 mg/kg/day/per oral ...
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A Novel Strategy for Enhance Potentiation of Meglumine anti-moniate against Leishmania major In Vitro
... as meglumine antimoniate (MA) and so- dium stibogluconate (Pentostam) are the standard recommended treatment for CL, but the major challenge in the treatment of leish- maniasis is the fact that the parasite ...
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Vol 28, No 4 (2018)
... intralesional meglumine antimoniate and combination of trichloroacetic acid 50% and intralesional meglumine antimoniate in the treatment of acute cutaneous leishmaniasis: a randomized clinical ...
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Vol 26, No 4 (2016)
... Our study is the first study to evaluate the efficacy of niosomal dapsone gel in the treatment of CL. Our results showed that efficacy of niosomal dapsone gel combined with intralesional meglumine ...
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Novel Approach to In Vitro Drug Susceptibility Assessment of Clinical Strains of Leishmania spp
... tively; n ⫽ 3), irrespective of the parasite-to-host cell ratio. The susceptibility readout was not affected by parasite ratios of be- tween 5 and 20 parasites per cell. Nevertheless, the lower ratio facilitates ...
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Vol 24, No 2 (2014)
... Therapeutic and adverse effects of standard- dose and low-dose meglumine antimoniate during systemic treatment of Syrian cutaneous leishmaniasis patients.. Siavash M.[r] ...
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A randomised factorial design clinical trial to investigate the impact of parenteral long acting oxytetracycline, foot trimming and flunixine meglumine on time to recovery from lameness and foot lesions in sheep lame with footrot
... http://www.wiley.com/bw/journal.asp?ref=0891-6640&site=1 Publisher statement: This is the pre-peer-reviewed version of the following article: Kaler, J.. et al. A randomised factorial design clinical trial to ...
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Evaluation of the contraceptive eff ects of carprofen, fl unixin meglumine and meloxicam in rats
... In a study carried out by Sookvanichsilp and Pulbutr (2002) the effectiveness of indomethacin and celecoxib in preventing implantation in rats was investigated. The researchers administered indomethacin (2.5 or 5 mg/kg ...
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Histpathological Anti-inflammatory Effects of Flunixin Meglumine and Ketoprofen on Excised Rat Tendon
... Twenty adult female albino Wistar rats (mean body weight of 209g with a standard deviation of 20g, from animal house of the university) were randomly divided into four groups. Each group was randomly allocated five ...
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The Effect of Novel Anti-inflammatory Drugs on the Cyclooxygenase Enzymes and Recovery of Mucosal Barrier Function
... flunixin meglumine significantly inhibited the recovery of ...flunixin meglumine on TER recovery has been previously described and has been attributed to the inhibition of prostaglandin-mediated closure of ...
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Improved oral bioavailability of poorly water-soluble glimepiride by utilizing microemulsion technique
... An attempt has thus been made to design, develop, and char- acterize a novel oil/water ME system of GM that may improve its oral bioavailability. Glimepiride microemulsion (GMME) was prepared according to pseudoternary ...
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Effects of flunixin meglumine on experimental tendon wound healing: A histopathological and mechanical study in rabbits
... Tendons are frequently targets of injury in sports and work. Whether nonsteroidal anti- inflammatory drugs (NSAIDs) have beneficial effects on tendon healing is still a matter of debate. This study was conducted to ...
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Cardiovascular Haemodynamics and Some Biochemical Profiles of Endotoxemic Buffalo Calves on Infusion of HSS, Flunixin Meglumine & Blood
... make a stock solution of 1 mg/ml. Endotoxin concentration of 5 µg/ml was prepared by dissolving 1 ml of stock solution in 199 ml of normal saline to make total volume 200 ml. The endotoxin was infused intra- venous @ 5 ...
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