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Metabolic Stress

Tamoxifen Mediated Metabolic Stress: Molecular Mechanism and Therapeutic Opportunities

Tamoxifen Mediated Metabolic Stress: Molecular Mechanism and Therapeutic Opportunities

... of metabolic stress 75 ...under metabolic stress, cells switch from glucose and glutamine to acetate as a carbon source for fatty acid ...

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Metabolic stress regulates cytoskeletal dynamics and metastasis of cancer cells

Metabolic stress regulates cytoskeletal dynamics and metastasis of cancer cells

... the metabolic regulators of tumor cell motility and metastasis are not ...overcome metabolic stress and promote tumor cell metastasis by limiting the activation of the nutri- ent sensor AMPK and ...

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Intermittent fasting causes metabolic stress and leucopenia in young mice

Intermittent fasting causes metabolic stress and leucopenia in young mice

... with stress induced by the periodic changes in food ...oxidative stress, whereas recorded perturbations on fasting day may be interpreted as metabolic stress and can be associated with hun- ...

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FGF21 underlies a hormetic response to metabolic stress in methylmalonic acidemia

FGF21 underlies a hormetic response to metabolic stress in methylmalonic acidemia

... response. Gene expression analysis in the fasted state showed differential clustering in a number of pathways, with significant enrichment of genes involved in drug metabolism and immune/inflammatory responses. ...

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The failing heart utilizes 3-hydroxybutyrate as a metabolic stress defense

The failing heart utilizes 3-hydroxybutyrate as a metabolic stress defense

... 3OHB augments respiratory efficiency in isolated heart mitochondria. Infusion of 3OHB resulted in a marked improvement in cardiac function and remodeling in the tachypacing model, together with evidence of increased ...

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Original Article Induction of apoptosis and autophagy in metastatic thyroid cancer cells by valproic acid (VPA)

Original Article Induction of apoptosis and autophagy in metastatic thyroid cancer cells by valproic acid (VPA)

... Metabolic stress is known to induce the pro- cess of autophagic flux. Our results revealed that VPA treatment induced autophagic vesicle associated form of LC3B (LC3B-II) in ARO cells after 48 h. It also ...

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Comparative transcriptomic profile analysis of fed-batch cultures expressing different recombinant proteins in Escherichia coli

Comparative transcriptomic profile analysis of fed-batch cultures expressing different recombinant proteins in Escherichia coli

... lar stress associated with the over-expression of recombi- nant ...oxidative stress (Vemuri et ...during stress, and act as anapleurotic reactions to replen- ish TCA cycle ...

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A study of the effects of glucose and oxygen deficiency on the function of synaptosomes: A model for ischaemia in immature and adult rat brain

A study of the effects of glucose and oxygen deficiency on the function of synaptosomes: A model for ischaemia in immature and adult rat brain

... The decision to use a reduced preparation for this investigation was taken to enable manipulation and measurement of the external and internal cellular environments, and so that biochemical changes during and after ...

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Aerobic exercise, training and modulation of the human immune system

Aerobic exercise, training and modulation of the human immune system

... 9 5 Summary Introduction Mechanical stress Metabolic stress The nature of exercise-induced damage to muscle Exercise-induced oxidative damage Measurement of free radical generation Delay[r] ...

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REGULATION OF TYPE 1 DIABETES AND ANTIOXIDANT ENZYMES TREATMENT WITH ALOE VERA IN ALLOXAN INDUCED DIABETIC RAT TESTIS

REGULATION OF TYPE 1 DIABETES AND ANTIOXIDANT ENZYMES TREATMENT WITH ALOE VERA IN ALLOXAN INDUCED DIABETIC RAT TESTIS

... radical stress gets amplified gradually and is propagated by an autocatalytic cycle of metabolic stress, testis tissue damage and cell death, leading to further increase in free radical production ...

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Oxidative Stress and Reproductive Inefficiencies: The Science, Evidences, and Solutions

Oxidative Stress and Reproductive Inefficiencies: The Science, Evidences, and Solutions

... oxidative stress and this occurs time-to-time in animals hence feeding antioxidant-rich feedstuff such as algae can contribute to improve internal antioxidant system in animals whereby all these enzymes will be ...

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Effect of dietary patterns on oxidative stress in Patiants with metabolic syndrome: Tehran Lipid and Glucose Study

Effect of dietary patterns on oxidative stress in Patiants with metabolic syndrome: Tehran Lipid and Glucose Study

... oxidative stress in MetS patients, concluded that the RESMENA (metabolic syndrome reduction in Navarra) diet (30% proteins, 30% lipids, 40% carbohydrates) specifically reduced the android fat mass and ...

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Sleepiness, inflammation and oxidative stress markers in middle-aged males with obstructive sleep apnea without metabolic syndrome: a cross-sectional study

Sleepiness, inflammation and oxidative stress markers in middle-aged males with obstructive sleep apnea without metabolic syndrome: a cross-sectional study

... Although statistical treatment was performed to ac- complish our purpose, one limitation of our study was the lack of homogeneity of the groups with respect to BMI, centralization of fat, insulin resistance and lipid ...

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Dynamic metabolic profiling of the marine microalga Chlamydomonas sp. JSC4 and enhancing its oil production by optimizing light intensity

Dynamic metabolic profiling of the marine microalga Chlamydomonas sp. JSC4 and enhancing its oil production by optimizing light intensity

... The levels of several key metabolites involved in the Cal- vin cycle (3-phosphoglyceric acid (3-PG), fructose-6- phosphate (F6P), and glucose-6-phosphate (G6P)) increased significantly along with cell growth, reaching ...

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AMELIORATIVE EFFECTS OF CLERODENDRUM PHILOMIDIS LINN  AGAINST OXIDATIVE STRESS INDUCED METABOLIC SYNDROME IN OBESE RATS

AMELIORATIVE EFFECTS OF CLERODENDRUM PHILOMIDIS LINN AGAINST OXIDATIVE STRESS INDUCED METABOLIC SYNDROME IN OBESE RATS

... Uric acid is another biochemical marker, which is generated from purines which arise from the metabolism of dietary and endogenous nucleic acids through the action of the enzyme xanthine oxidase. It is an endogenous ...

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EFFECT OF ALTERED P HON THE LIPID METABOLISM OF PRAWN LITOPENAEUS VANNAMEI

EFFECT OF ALTERED P HON THE LIPID METABOLISM OF PRAWN LITOPENAEUS VANNAMEI

... In the presence of altered PH disorders occurs in the lipid organization of biological membranes which result in alterations in the activity of a number of membrane bound enzymes (ohkawa et al., 1979). Lipid peroxidation ...

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Associations of retinol-binding protein 4 with oxidative stress, inflammatory markers, and metabolic syndrome in a middle-aged and elderly Chinese population

Associations of retinol-binding protein 4 with oxidative stress, inflammatory markers, and metabolic syndrome in a middle-aged and elderly Chinese population

... multiple metabolic abnormalities, including central obesity, dys- lipidemia, elevated blood pressure, hyperglycemia and insulin ...oxidative stress and dysregulated proinflammatory responses in tissues such ...

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Increased oxidative stress in obesity and its impact on metabolic syndrome

Increased oxidative stress in obesity and its impact on metabolic syndrome

... of metabolic syndrome. Here we report that increased oxidative stress in accumulated fat is an important pathogenic mechanism of obesity-associated metabolic ...oxidative stress in humans and ...

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Key words

Key words

... rocyte antioxidant enzymes and serum free thiol content. The trend of the association differed, being positive for SOD1 and free thiol content and negative for GPx1 and catalase. Accordingly, SOD1 and thiol content were ...

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Photorespiration: metabolic pathways and their role in stress protection

Photorespiration: metabolic pathways and their role in stress protection

... (measured in air), poor plant growth and alterations in the chloroplast structure (Migge et al. 1999). It has been suggested that photorespiration is important for energy dissipation to prevent photoinhibition (Osmond ...

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