Mhc class i antigens
SUSCEPTIBILITY OF HUMAN WM MELANOMA CELL LINES TO NK AND LAK CYTOTOXICITY AND THEIR RELEVANCE TO THE LEVEL OF MHC CLASS I AND ICAM-l ANTIGEN EXPRESSION
... of class I anti gens. Thus either MHC class I antigens do not function as specific protective elements for allogeneic NK cell cytoly sis or possibly the tumor cells may lack ...
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Signaling at neuro/immune synapses
... NK cells are innate immune cells that work in concert with cytotoxic T cells to defend against viruses by using inhibitory receptors that bind MHC class I antigens and host-derived or vi[r] ...
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Role of de novo protein synthesis in target cells recognized by cytotoxic T lymphocytes specific for vesicular stomatitis virus.
... Target cells sensitized with UV-VSV were used to determine whether viral antigens associate only with newly synthesized class I MHC molecules by incubating the cells with the protein syn[r] ...
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Expression of class I and class II major histocompatibility antigens on human hepatocellular carcinoma
... express class I MHC antigens and among them, three poorly differentiated human HCC cell lines also express class II MHC ...the class I and class II ...
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The Major Histocompatibility Complex Class I Genes of Zebrafish.
... primary antigens responsible for determining transplant compatibility (Klein 2001), MHC molecules also play a central role in adaptive immunity through presenting antigens to T ...cells. MHC ...
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Varicella-Zoster Virus Productively Infects Mature Dendritic Cells and Alters Their Immune Function
... to MHC class II antigens, ...expressed MHC class II in the absence of VZV antigen ex- pression ...to MHC class I, MHC class II, CD1a, CD80, CD83, and ...
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Analysis of rabbit cell surface (CD) antigens by means of cross reactive monoclonal antibodies with specificity for cattle CD antigens
... unrecognized antigens in a number of different ...defined) antigens (CD9, CD18, CD45R, CD41/61, CD62L, MHC class I and bovine IgG light chain molecule) were assayed for reactivity with ...
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Cytotoxic T lymphocyte responses to Ras protein
... peptide antigens, which if presented on the cell surface by class I MHC molecules may be recognized by cytotoxic T ...of MHC class I was demonstrated using the H-2® ...
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The role of citrullination of central nervous system proteins in multiple sclerosis
... foreign antigens but in the absence of inflammatory stimuli express low levels of MHC class II and costimulatory molecules, and are therefore unable to activate T cells (Mahnke et ...of MHC ...
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A Novel Bat Herpesvirus Encodes Homologues of Major Histocompatibility Complex Classes I and II, C-Type Lectin, and a Unique Family of Immune-Related Genes
... (iv) MHC-related proteins. Some betaherpesviruses encode multiple MHC class I homologues, such as UL18 and UL142 of HCMV (24) and CCMV (21), m144 of MCMV (64), R144 of RCMV (89), and gp147, ...
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Virus-Like Particles as Carriers for T-Cell Epitopes: Limited Inhibition of T-Cell Priming by Carrier-Specific Antibodies
... (MHC) class I pathway. In general, exogenous antigens reach the MHC class II pathway while only endogenous antigens efficiently fuel the MHC class I ...
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TARGETING TOOLS FOR A DNA VACCINE CARRIER, A DESIGN IN PREVENTION OF CANCER
... peptide antigens on the cell surface of an antigen-presenting cell in association with a class major histocompatibility complex (MHC) ...to MHC molecules is allele specific, and correlates ...
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Simian immunodeficiency virus induces expression of class II major histocompatibility complex structures on infected target cells in vitro.
... Although MHC-I as well as MHC-II antigens are expressed in greater quantity on the surfaces of chronically SIV-infected cells than on uninfected cells, we were unable to demonstrate the [r] ...
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Indirect T cell allorecognition of donor MHC class I alloantigens
... H-2L‘^ MHC molecules suggests that about 8 5 -9 0 % of MHC specific clones need peptide to be present ...HLA class I antigens ...Is MHC dependent ...that MHC conformation ...
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Methyldopa blocks MHC class II binding to disease specific antigens in autoimmune diabetes
... In our clinical trial involving the treatment of patients with recent-onset T1D with methyldopa, we observed a 40% reduction in DQ8 antigen presentation when using PBMCs as APCs (Figure 5D). Presumably, methyldopa is ...
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Direct Binding of Human Immunodeficiency Virus Type 1 Nef to the Major Histocompatibility Complex Class I (MHC-I) Cytoplasmic Tail Disrupts MHC-I Trafficking
... surface MHC-I antigens, and colocalizes with MHC-I in the perinuclear ...and MHC-I colocalize in the perinuclear region of ...and I), and HLA-A2 was detected by ...
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Autophagy in Innate Recognition of Pathogens and Adaptive Immunity
... type I IFN ...in MHC class II processing and presentation of intracellular antigens to CD4 T ...Intracellular antigens are engulfed by autophagosomes, transported to MHC ...
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v-rel induces expression of three avian immunoregulatory surface receptors more efficiently than c-rel.
... In this study, we demonstrated that three avian immunoregulatory receptors, major histocompatibility MHC antigens class I and class II as well as the interleukin-2 receptor IL-2R, were i[r] ...
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Downregulation of MHC class I molecules by human cytomegalovirus-encoded US2 and US11
... of MHC class I, formal proof is still lack ing ...uman MHC class I h eav y ch ain construct and transd uced th ese cells w ith a retrov iral v ector encod ing b oth U S 1 1 and E ...
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Review On Immunotoxicology: An Emerging Discipline
... The main objective of immunotoxicology is to protect humans and animals against the harmful effects of chemical factors present in the environment, to develop and check immunotherapeutic products. Harmful effects of ...
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