miR-503
Original Article miR-503 inhibits cell proliferation and induces apoptosis in colorectal cancer cells by targeting E2F3
... with miR-503 in CRC. The above findings suggest that miR-503 plays its sup- pressive role in CRC by direct targeting ...that miR-125b could sup- press bladder cancer cells to form ...
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MiR-503 inhibits hepatocellular carcinoma cell growth via inhibition of insulin-like growth factor 1 receptor
... of miR-503 in HCC has not been fully ...that miR-503 was sig- nificantly downregulated in HCC tissues compared to nontumorous liver ...lower miR-503 levels were associated with ...
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<p>miR-503 Inhibits Proliferation, Migration, And Angiogenesis Of Glioma By Acting On VEGFA Through Targeting LRIG2</p>
... that miR-503 is involved in angiogenesis during hypoxia, diabetes mellitus- induced impairment, endometriosis, and other ...with miR-503 overexpression (Figure 1A – ...that ...
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The miR-503 cluster is coordinately under-expressed in endometrial endometrioid adenocarcinoma and targets many oncogenes, cell cycle genes, DNA repair genes and chemotherapy response genes
... the miR-503 cluster was determined by quanti- tative PCR and differences in expression between EEA and benign tissues were assessed via the standard ΔΔCt ...the miR-503 cluster is ...
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Decreased miR-503 expression in gastric cancer is inversely correlated with serum carcinoembryonic antigen and acts as a potential prognostic and diagnostic biomarker
... of miR-503 in samples were measured by real-time reverse transcription quantitative polymerase chain reaction ...The miR-503 expression level was calculated by cycle threshold (Ct) values with ...
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Original Article miR-503-3p suppresses cell viability and promotes cell apoptosis in cancer cells
... of miR- 503-3p derived from 3’ ends of pre-miR-503 has never been ...that miR-503-3p inhibits tumor cell viability and induces cell ...the miR-503-3p participating ...
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<p>Long Non-coding RNA BLACAT1 Induces Tamoxifen Resistance in Human Breast Cancer by Regulating miR-503/Bcl-2 Axis</p>
... We found that BLACAT1 is mostly located in the cyto- plasm of MCF-7/TR and T47D/TR cells (Figure 3A), indicating the ceRNA potential for BLACAT1. Through the Starbase database (http://starbase.sysu.edu.cn/index. php), we ...
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MiR-503 suppresses cell proliferation and invasion of gastric cancer by targeting HMGA2 and inactivating WNT signaling pathway
... of miR- 503 showed little ...via miR- 503/CACUL1 signaling ...of miR-503 in GC, and HMGA2 over- expression promoted GC cell proliferation and ...by miR-503 on GC ...
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<p>Serum miR-503 is a Candidate Biomarker for Differentiating Metabolic Healthy Obesity from Metabolic Unhealthy Obesity</p>
... This research still has some limitations. Although some people not overweight or obese, but their plasma sugar and serum TG may be abnormal, namely MUNW subjects, due to fewer samples were collected in this group, MUNW ...
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<p>LncRNA-MALAT1 regulates proliferation and apoptosis of ovarian cancer cells by targeting miR-503-5p</p>
... 35 miR-200s/ZEB2, 36 ATM- CHK2, 37 and ...Moreover, miR-9 secreted from tumor cells can activate JAK-STAT3 signaling path- way by suppressing the expression of SOCS5, conse- quently leading to deterioration ...
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Original Article Down-regulation of miR-503 expression predicate advanced mythological features and poor prognosis in patients with NSCLC
... between miR-503 levels and OS Kaplan-Meier analysis with log-rank test was used to calculate the effect of miR-503 expres- sion on patient survival (shown in Figure ...of miR- ...
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Can MiR-503 be used as a marker in diabetic patients with ischemic stroke?
... compare miR-503 level in 4 groups of diabetic patients with stroke (I), non-diabetic patients with stroke (II), diabetic patients without stroke (III) and healthy ...of miR-503 including ...
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Arcyriaflavin a, a cyclin D1–cyclin-dependent kinase4 inhibitor, induces apoptosis and inhibits proliferation of human endometriotic stromal cells: a potential therapeutic agent in endometriosis
... miR-503 has been demonstrated to downregulate cyc- lin D1 expression and induce G0/G1 phase cell cycle ar- rest in several cell types [5, 7, 14]. We confirmed that arcyriaflavin A induced cell cycle arrest ...
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MicroRNA 503 inhibits the G1/S transition by downregulating cyclin D3 and E2F3 in hepatocellular carcinoma
... which miR-503 inhibits the G1/S transition, miRNA target pre- diction databases, such as TargetScan, miRanda, and PicTar, were employed to predict miR-503 ...putative ...
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<p>MicroRNA-503 Inhibits Non-Small Cell Lung Cancer Progression By Targeting PDK1/PI3K/AKT Pathway</p>
... of miR-503 in NSCLC progression, A549 cells or PC9 cells were transfected with miR-503 mimic or miR-503 inhibitor to up-regulate or downregulate miRNA-503 expression, ...
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Original Article MicroRNA-503 attenuates hypoxia-induced pulmonary artery smooth muscle cell proliferation through directly targeting Bcl-2
... of miR-503 in ...of miR-503 and explore its modulatory mechanism in ...of miR-503 in IPAH patients’ sera were evidently ...with miR-503 mimics, overexpression of ...
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p75NTR dependent activation of NF κB regulates microRNA 503 transcription and pericyte–endothelial crosstalk in diabetes after limb ischaemia
... antagonizing miR-503 in mice improved the post-ischaemic reparative neovascularization and restores the expression of target genes in the diabetic and ischaemic limb muscles 10 ...of miR-503 ...
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Endothelial exosomes contribute to the antitumor response during breast cancer neoadjuvant chemotherapy via microRNA transfer
... of miR- 503 target genes that displayed many links with each other to identify the genes responsible for the observed anti- tumor ...of miR-503, CCND2 and CCND3, which are downregulated at the ...
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Volume 20 - Article 21 | Pages 503–540
... To address these issues, we conduct a series of data quality analyses for the MDICP data, including comparisons of the data with the Malawi Demographic and Health Surveys (MDHS) and a[r] ...
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Secure IoT Network Structure Based on Distributed Fog Computing, with SDN/Blockchain
... higher efficiency in terms of computing resources utilization (e.g. processing, storage and energy) 503. and latency[r] ...
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