Mutation bias
Determining the Mutation Bias of Favipiravir in Influenza Virus Using Next-Generation Sequencing
... the mutation bias of favipiravir in vivo found an excess of transversion mutations ...a bias, since mutations from preexisting polymorphisms or mutations that are positively selected will be counted ...
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Negative Covariance Suggests Mutation Bias in a Two-Locus Microsatellite System in the Fish Sparus aurata
... page is the main mechanism for this expansion, a long Whether our observation is a result of natural selec- repeat allows more replication slippage events than a tion or mutation bias remains to be resolved ...
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Long Microsatellite Alleles in Drosophila melanogaster Have a Downward Mutation Bias and Short Persistence Times, Which Cause Their Genome-Wide Underrepresentation
... in mutation-accumulation lines suggests that long alleles have a mutation bias toward a reduction in the number of repeat ...This bias causes the short persistence times of long microsatellite ...
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Differentiating Between Selection and Mutation Bias
... Problems arise because the rate of preferred to unpreferred substitu- tions (per site) is lower than the rate of unpreferred to preferred substitutions when a sequence [r] ...
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Likelihood Analysis of Asymmetrical Mutation Bias Gradients in Vertebrate Mitochondrial Genomes
... individual mutation components to the ancestral vertebrate substitution pattern, here we analyze a large data set of complete vertebrate mitochondrial genomes in a phylogeny-based likelihood ...of mutation ...
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Smooth operator? Understanding and visualising mutation bias
... 4 further demonstrates that, unlike onsiderations of mutation drift al ulated as the expe ted mutant destination attention to the manner in whi h skewness al ulated as the di eren e be[r] ...
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The Evolution of Isochores: Evidence From SNP Frequency Distributions
... to mutation bias using two new tests, which do not assume compositional ...neutral mutation bias fit the frequency distributions of SNPs segregating in low- and medium-GC-content regions of ...
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Depletion of somatic mutations in splicing associated sequences in cancer genomes
... we would like to suggest the following reasons as plaus- ible causes for this selection. The obvious first reason is loss-of-function of a gene due to truncation or absence of functional protein domains which are ...
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Variation in Mutation Dynamics Across the Maize Genome as a Function of Regional and Flanking Base Composition
... in mutation dy- namics within a ...on mutation dynamics in maize nuclear DNA: there is a relationship between flanking base composition and mutation bias, an in- creased rate of transitions at ...
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Dietary nitrogen alters codon bias and genome composition in parasitic microorganisms
... codon bias have revealed that selection acting on translational efficiency in Mollicutes is marginal ...both mutation bias and selection acting on the nitrogen content of coding ...usage bias ...
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Reducing decision errors in the paired comparison of the diagnostic accuracy of screening tests with Gaussian outcomes
... trial bias, a bias for which there is no other cor- rection ...trial bias. The proposed method will counteract bias in the paired trials and allow inves- tigators to compare screening tests ...
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Objectivity and Bias
... The twin goals of this essay are: (i) to investigate a family of cases in which even asymptotic objectivity is beyond our reach; and (ii) to consider the implications of such cases for three sorts of approaches prominent ...
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Selective Attention and Childhood Anxiety: The Associations Among Attention, Memory, Interpretive Biases and Anxiety
... Attention Bias scores on the picture Dot Probe Discrimination ...greater bias towards attending to threat pictures as compared to low anxious children (participants with scores falling 1 SD above the sample ...
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Physically active lessons in schools and their impact on physical activity, educational, health and cognition outcomes: a systematic review and meta-analysis
... two studies assessing fluid intelligence 60 72 and one assessing executive functions 40 . While the Q-test of heterogeneity (Q (2) = 5.98, p=0.05) was marginally significant, a random-effects model was applied to the ...
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The anterior bias in visual art: The case of images of animals
... With respect to the asymmetry of the bias, the difference was not significant for right facing animals and for left facing animals. The lack of a significant difference for right facing animals is consistent with ...
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Topical NSAIDs for chronic musculoskeletal pain in adults
... One potential bias is that clinical trials for topical NSAIDs may not have been published. One previous review did find previously unpublished trials (Moore 1998a), but a subsequent attempt that included extensive ...
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CCD photometry and the stellar content of the central region of IC 1805
... When the in the read noise example, if 16 bias frames an mean bias is bias frame is 1/16 subtracted from will choice of average V1-0625^ = mean or = 6, following: a single bias each pixe[r] ...
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Time loss bias and reducing the bias by instruction
... As expected, people answered the time loss cases in a biased way. The answers cannot be explained by the correct formula, the ratio rule or the difference rule. The answers came closest to the ratio rule, although not ...
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X-Linked Genes Evolve Higher Codon Bias in Drosophila and Caenorhabditis
... codon bias of an individual gene such as protein length, GC content, and expression ...codon bias, we sampled autosomal genes to match the distribution of X-linked genes with respect to other gene ...
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Review Article Comparative effectiveness of acupuncture and HRT interventions for premature ovarian failure: a bayesian meta-analysis
... of bias assessed for included studies were presented in Table ...of bias was low for the random sequence generation pro- cess for two included studies (Luo JJ, 2015 and Liu LJ, ...of bias for ...
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