Nuclear-antigen
A Study Of Proliferating Cell Nuclear Antigen Expression in Benign, Borderline and Malignant Epithelial Tumours of Ovary
... A Study Of Proliferating Cell Nuclear Antigen Expression in Benign, Borderline and Malignant Epithelial Tumours of Ovary ORIGINAL ARTICLE A Study of Proliferating Cell Nuclear Antigen Ex~ression in Be[.] ...
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Cellular Target Genes of Epstein-Barr Virus Nuclear Antigen 2
... Epstein-Barr virus (EBV) nuclear antigen 2 (EBNA-2) is a key determinant in the EBV-driven B-cell growth transformation process. By activating an array of viral and cellular target genes, EBNA-2 initiates a ...
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Expression in COS-1 cells of Epstein-Barr virus nuclear antigen from a complete gene and a deleted gene.
... Sources of antibody were human sera which were characterized with respect to their content of antibody to early antigen, capsid antigen, and EBNA; their reactivity to the nuclear antigen[r] ...
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Epstein-Barr virus nuclear antigen 3C is a transcriptional regulator.
... (EBV) nuclear antigen 3C (EBNA-3C) is one of five viral nuclear proteins that are essential for EBV-induced immortalization of primary human B lymphocytes in ...
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Induction of the autoantigen proliferating cell nuclear antigen in T lymphocytes by a mycobacterial antigen
... Mycobacteria have been implicated in the pathogenesis of autoimmunity. To determine the potential effect of mycobacterial antigens on peripheral blood mononuclear cells (PBMC), we analyzed PBMC incubated with the ...
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Epstein-Barr Virus Nuclear Antigen Leader Protein Coactivates EP300
... ABSTRACT Epstein-Barr virus nuclear antigen (EBNA) leader protein (EBNALP) is one of the first viral genes expressed upon B-cell infection. EBNALP is essential for EBV- mediated B-cell immortalization. ...
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Nuclear Import of Epstein-Barr Virus Nuclear Antigen 1 Mediated by NPI-1 (Importin α5) Is Up- and Down-Regulated by Phosphorylation of the Nuclear Localization Signal for Which Lys379 and Arg380 Are Essential
... (EBV) nuclear antigen 1 (EBNA-1) is essential for replication of episomal EBV DNAs and maintenance of ...on nuclear translocation of Ser phosphorylation of the EBNA-1 nuclear localization ...
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Conserved Region CR2 of Epstein-Barr Virus Nuclear Antigen Leader Protein Is a Multifunctional Domain That Mediates Self-Association as well as Nuclear Localization and Nuclear Matrix Association
... (EBV) nuclear antigen leader protein (EBNA-LP) contains various numbers of W1W2 repeats and a unique carboxyl-terminal Y1Y2 ...mediating nuclear localization, nuclear matrix association, and ...
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Improved immunofluorescence antigens for detection of immunoglobulin M antibodies to Epstein Barr viral capsid antigen and antibodies to Epstein Barr virus nuclear antigen
... Viral capsid antigen production was stimulated with a phorbol ester, and the Epstein-Barr virus nuclear antigen cells were fixed in suspension to eliminate loss of antigen during the dry[r] ...
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Functional domains of Epstein-Barr virus nuclear antigen EBNA-1.
... To identify the EBNA-1 nuclear localization signal, small oligonucleotides representing EBNA-1 sequences that encode clusters of basic peptides were transferred into two different vector[r] ...
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Epstein-Barr Virus Nuclear Antigen 1 Hijacks the Host Kinase CK2 To Disrupt PML Nuclear Bodies
... We then examined whether EBNA1 affected the degree to which USP7 and CK2 were associated with PML NBs. These experiments were performed by expressing EBNA1 in CNE2 cells by transient transfection and imaging or ...
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The Viral Latency-Associated Nuclear Antigen Augments the B-Cell Response to Antigen In Vivo
... on antigen-dependent B-cell survival, proliferation, and differentiation through direct interaction with the BCR molecule (24, ...is nuclear localized, and thus far most of its function- ality has been ...
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Identification of an Epstein-Barr virus nuclear antigen by fluoroimmunoelectrophoresis and radioimmunoelectrophoresis.
... Pooled human serum 10 gave a pattern similar to serum 9, except that a faint additional antigen band was detected in B95-8/PAA and Raji at 81K data not shown.. Figure 2B and C show the F[r] ...
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Biochemical characterization of Epstein-Barr virus nuclear antigen 2A.
... We do not know why only a small portion of the EBNA-2A protein that was solubilized from the nuclear matrix fraction by boiling with SDS-containing buffer could be immunoprecipitated com[r] ...
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Epstein Barr Virus Antibodies in Kawasaki Disease
... capsid antigen (VCA) IgG and IgM, anti-diffuse and restricted early antigen IgG (anti-EADR IgG), and the anti-EBV deter- mined nuclear antigen IgG (anti-EBNA IgG) were examined in 29 KD ...
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Monteith_unc_0153D_15868.pdf
... allowing nuclear antigens to leak into the cytosol ...recognize nuclear antigen and promote pyroptosis and innate immune activation against self-antigens ...
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Serum EBV antibodies and LMP-1 in Polish patients with oropharyngeal and laryngeal cancer
... BL: Burkitt ’ s lymphoma; del-LMP1: deletion variant of latent membrane protein 1; EA: Early antigen; EBNA: Epstein-Barr nuclear antigen; EBV: Epstein-Barr virus; EBVCA: Epstein-Barr vir[r] ...
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Nuclear localization signals, but not putative leucine zipper motifs, are essential for nuclear transport of hepatitis delta antigen.
... Further studies with other mutant constructs of the N terminus of HDAg indicated that amino acid residues 35 to 50 of HDAg possess a nuclear localization signal NLS1, because N5OZ, conta[r] ...
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Epstein-Barr virus-specific intrathecal oligoclonal IgG production in relapsing-remitting multiple sclerosis is limited to a subset of patients and is composed of low-affinity antibodies
... by antigen- specific immunoblotting (ASI) as reported elsewhere [31] using, as the target antigen, a crude viral lysate con- taining a high concentration of EBV antigens, including VCA, EBNA, early ...
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Hmga2is required for canonical WNT signaling during lung development
... 4°C, dehydrated over a graded series of alcohol, and paraf- fin embedded. Sections of 4 μm were prepared on a microtome (Leica). Antigen retrieval was performed by microwave heating for 8 minutes using 1 mM EDTA ...
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