ondansetron HCl
Simultaneous Estimation of Ondansetron HCL and Promethazine HCL by UV-Spectroscopy and Ondansetron HCL and Paracetamol by HPTLC in Bulk and Pharmaceutical Dosage Forms.
... of Ondansetron Hcl and Promethazine Hcl was found to 310 nm and 250 ...nm. Ondansetron Hcl and Promethazine Hcl obey linearity within the concentration range of 5-25 µg/ml and ...
88
FORMULATION DEVELOPMENT AND EVALUATION OF ONDANSETRON HCL NATURAL VESICLE OF LIPOSOME FOR CHEMOTHERAPY INDUCED NAUSEA VOMITTING
... The guinea pig skin was mounted on modified franz diffusion cell. In-vivo evaluation of permeation rates of preliminary and optimized liposomal (F4) batches was performed respectively and drug solution containing same ...
15
DEVELOPMENT OF ONDANSETRON HCL FAST DISINTEGRATING TABLETS USING 32 FULL FACTORIAL DESIGN
... of Ondansetron HCl with a view to enhance patient compliances and dissolution rate by direct compression method using 3² full factorial ...N HCl), short-term stability (at 40º/75 % RH for 6 mo) and ...
6
EFFECT OF PERMEATION ENHANCER ON EX VIVO PERMEATION OF ONDANSETRON HCl BUCCAL TABLETS
... CONCLUSION: Ondansetron HCl permeated through the buccal mucosa by passive diffusion was confirmed by ex-vivo permeation studies. The formulation (F4) with 3:1 ratio of CP and HPC gave maximum drug release ...
5
FORMULATION AND EVALUATION OF ONDANSETRON HCL TRANSDERMAL PATCH
... The matrix-type transdermal patches containing Ondansetron Hcl were prepared using different concentrations of ethyl cellulose and Eudragit S 100. The polymers in different concentrations were dissolved ...
21
DEVELOPMENT AND EVALUATION OF ONDANSETRON HCL MICROBALLOONS FOR TREATMENT OF EMESIS
... Accurately weighed loaded microballons (5 mg) were placed in 50 ml of ethanol/methanol in 100 ml glass bottles. The later were horizontally shaken at 37°C at predetermined time intervals. Aliquot samples were withdrawn ...
6
DESIGN AND DEVELOPMENT OF TASTE MASKED ORAL DISINTEGRATING TABLET OF ONDANSETRON HYDROCHLORIDE
... The Ondansetron HCl promised formulations OHS4, OHS8, OHS12 shows nearly faster drug release. The formulation OHS4, OHS8, and OHS12 90% of drug released in 6min, 8min and 10min respectively when compare to ...
7
Hydroxypropyl-β-Cyclodextrin (HBC) Multicomponent Complexation and pH independent controlled release delivery system to Improved Dissolution and oral Bioavailability of Ondansetron HCI
... soluble Ondansetron HCl using two different types of formulations (solid dis- persions and Matrix tablets) by using Multicomponent complexation was attempt to progress the dissolution performance of the ...
11
Development and Characterization of Oro Dispersible Tablets of Diltiazem Hydrochloride.
... Sreenivas et al.,352006 developed the formulation and evaluation of ondansetron HCL fast dissolving tablet by using super disintegrating agent like sodium starch glycolate and crospovido[r] ...
136
Formulation and In-vitro Evaluation of Sublingual Tablets of Ondansetron Hydrochloride using Coprocessed Excipients
... sion) and based on numerical optimization the global best formulation (best values of excipients) was deter- mined. In a mixture design, the level of a single com- ponent cannot be changed independently and the sum of ...
11
Vol 2, No 3 (2010)
... Ondansetron HCl is a potent, highly selective 5-HT3 receptor-antagonist used to prevent nausea and vomiting, mainly in patients undergoing chemotherapy and radiation ...of Ondansetron HCl ...
5
Formulation and Evaluation of Mouth Dissolving Tablets of Ondansetron Hydrochloride
... disintegration. Ondansetron HCl is a highly selective and potent antagonist of 5-hydroxytryptamine at 5HT3 receptors in the gastrointestinal tract where it blocks both sites of serotonin induced nausea and ...
11
Multiparticulate system for colon targeted delivery of ondansetron
... at that time formulations were exposed to pH 7.4, which is above the solubility of the eudragit S-100 polymers. EC3 formulation containing 1:10 core/coat ratio releases only 3.64±0.34% of ondansetron within 4 h. A ...
7
Formulation and Evaluation of Orodispersible Tablets of Ondansetron Hydrochloride
... Jayashri G.Mahore et.al, (2010) In the present work, orodispersible tablets of metoclopramide HCl were designed by preparing tasteless complexes of metoclopramide HCl with weak cation ion exchange resins ...
105
Effect of Ondansetron on Convulsions and its Interactions with Phenytoin.
... were ondansetron as the investigational drug and diazepam and phenytoin as standard anticonvulsant ...for ondansetron (Emset,Cipla Ltd), ...market. Ondansetron and diazepam were given one hour prior, ...
7
On the discrepancy of HCl processing in the core of the wintertime polar vortices
... step, HCl decreases particularly strongly during two periods in mid-June and ...the HCl depletion rate and PSC occurrence seem to have rel- ative maxima around 11 June ...of HCl deple- tion), minima ...
20
Ondansetron and Metoclopramide Can Prevent Intrathecal Sufentanil-Induced Pruritus
... The required dosage and frequency of naloxone and metoclopramide injection used as rescue medications, were also decreased by using metoclopramide and ondansetron in this study which was also demonstrated in ...
8
FORMULATION AND EVALUATION OF BILAYER TABLETS OF METFORMIN HCL AND PIOGLITAZONE HCL
... Pioglitazone HCl and Metformin HCl was accurately weighed from powdered bilayered tablets and it was dissolved in methanol and distilled water respectively to form a clear ...
15
Design and Develop Bilayered Oral Sustained Matrix Tablets of Pioglitazone Hydrochloride and Metformin Hydrochloride
... A sufficient polymer concentration in the hydrophilic matrix system is required to form a uniform gel barrier around the tablet upon hydration. This barrier is expected to prevent the drug from immediate release into ...
111
Effects of Ondansetron on Xylazine Induced Emesis in Cats
... of ondansetron (Demitron 2 mg/ml, Tehran Chemie pharmaceutical ...xylazine HCl (Alfasan, 2%, the Netherlands, IM) was evaluated against saline solution ...treatment). Ondansetron was injected in ...
8