Palmitic acid
Palmitic acid-induced lipotoxicity promotes a novel interplay between Akt-mTOR, IRS-1, and FFAR1 signaling in pancreatic β-cells
... fatty acid receptor 1 (FFAR1) is G‑protein coupled receptor predominantly expressed in pancreatic β‑cells that is activated by a variety of free fatty acids ...using palmitic acid ...
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Effect of α-linolenic acid on endoplasmic reticulum stress-mediated apoptosis of palmitic acid lipotoxicity in primary rat hepatocytes
... that palmitic acid causes obvious cell death in primary rat ...the palmitic acid causes an obvious degree of ER stress in primary rat ...to palmitic acid ...a-linolenic ...
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Optimization of Palmitic Acid Composition in Crude Oleic Acid to Provide Specifications of Titer and Cloud Point of Distillate Oleic Acid using a Flash Distiller
... of palmitic acid becomes the main staple in raising levels of unsaturated fatty acids, oleic acid on the COA and ...(lauric acid, myristate, hydrocarbons, aldehydes and/or ketones, pigments, ...
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Ameliorative effects of polyunsaturated fatty acids against palmitic acid-induced insulin resistance in L6 skeletal muscle cells
... fatty acid metabolites DAG and ...[7,8]. Palmitic acid is a stronger inducer of the accumulation of these metabolites and the transcrip- tional activity of NF- B compared as stearic acid [3], ...
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Curcumin protects against palmitic acid-induced apoptosis via the inhibition of endoplasmic reticulum stress in testicular Leydig cells
... Background: Palmitic acid (PA) is a common saturated fatty acid that induces apoptosis in various types of cells, including testicular Leydig ...4-phenylbutyric acid (4-PBA, an endoplasmic ...
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Original Article Polyenylphosphatidylcholine alleviates palmitic acid-induced apoptosis in HepG2 cells via inhibiting endoplasmic reticulum stress
... Abstract: Polyenylphosphatidylcholine (PPC) can reduce hyperlipidemia, relieve arteriosclerosis and decrease tri- glyceride. The aim of the present study was to investigate whether polyenylphosphatidylcholine (PPC) could ...
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Synthesis of fatty ethanolamides from lauric and palmitic acid: Optimization using Response Surface Methodology
... and palmitic acid in the synthesis of fatty ethanolamide from monoethanolamine using zirconium (IV) chloride as a metal catalyst and n-hexane with isopropanol as a mixed ...lauric acid conversion, ...
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Myristic acid potentiates palmitic acid-induced lipotoxicity and steatohepatitis associated with lipodystrophy by sustaning de novo ceramide synthesis
... [1]. Palmitic acid (PA) is the most abundant saturated fatty acid (SFA) found in Western diets and processed foods and it is known to cause lipoapoptosis in hepatocytes through different mechanisms, ...
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Contribution of Palmitic Acid to Epidermal Morphogenesis and Lipid Barrier Formation in Human Skin Equivalents
... Abstract: The outermost barrier layer of the skin is the stratum corneum (SC), which consists of corneocytes embedded in a lipid matrix. Biosynthesis of barrier lipids occurs de novo in the epidermis or is performed with ...
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Green diesel production through simultaneous deoxygenation of palmitic acid and desulfurization of 4,6-Dimethyl-dibenzothiophene over commercial CoMo/Al2O3
... of palmitic acid or by-products generated through the side reactions to some catalyst active sites as well as by blocking catalyst pores, and (3) gradual leaching of sulfur, metal oxidation, and metal ...
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Oxidation of linoleic and palmitic acid in pre hibernating and hibernating common noctule bats revealed by 13C breath testing
... fed palmitic acid had lower TOR than noctule bats after the migration period (this study; see also Voigt et ...linoleic acid than for palmitic ...linoleic acid has not been measured ...
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Synthesis of palmitoyl ethanolamide from palmitic acid and monoethanolamine: Analysis of variance and surfactant characteristics
... Therefore, the purpose of the study is to analyze of variance and verification test of a mathematical model, which states the relationship between substrate mole ratio, catalyst concentration and solvent ratio to the ...
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Epinephrine plasma thresholds for lipolytic effects in man: measurements of fatty acid transport with [l 13C]palmitic acid
... To determine the plasma epinephrine thresholds for its lipolytic effect, 60-min epinephrine infusions at nominal rates of 0.1, 0.5, 1.0, 2.5, and 5.0 micrograms/min were performed in each of four normal young adult men ...
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Palmitoleic acid prevents palmitic acid-induced macrophage activation and consequent p38 MAPK-mediated-skeletal muscle insulin resistance
... palmitoleic acid alone generated CM that was insulin sensitising, as well as increas- ing basal glycogen synthesis, while addition of palmitoleic acid to a palmitic acid incubation is also ...
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Melatonin attenuates palmitic acid-induced mouse granulosa cells apoptosis via endoplasmic reticulum stress
... Fig. 9 Effects of melatonin on TG-treated mouse granulosa cell viability, cell apoptosis and ER stress at 24 h. a Cell viability measured by an MTT assay. b, c Apoptosis detected via flow cytometry. d Western blot assays ...
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Chlorogenic acid against palmitic acid in endoplasmic reticulum stress-mediated apoptosis resulting in protective effect of primary rat hepatocytes
... with palmitic acid elevated cell ...Chlorogenic acid could inhibit ER stress induced cell death and levels of indicators of ER stress caused by palmitic ...
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Neuroprotective effects of vitamin D on high fat diet- and palmitic acid-induced enteric neuronal loss in mice
... PA: Palmitic acid; PBS: Phosphate buffered saline; PDI: Protein disulphide isomerase; PDIA3: Protein disulphide isomerase family A member 3; PDK4: Pyruvate dehydrogenase kinase 4; PEPCK: Phosphoenolpyruvate ...
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Cannabidiol Attenuates Palmitic Acid-Induced Injury in Cultured Hepatocytes Through Promoting Autophagic Flux
... (2) palmitic acid (palmitic acid, PA, 800 mu mol/L, American Sigma company, cargo number P0500) stimulation group; (3) PA (800 mu mol/L) +CBD (5 mu mol/L, American Sigma company, cargo number ...
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Palmitic acid mediates hypothalamic insulin resistance by altering PKC θ subcellular localization in rodents
... i.c.v. palmitic acid (but not oleic acid) attenuates insulin-induced sup- pression of hepatic glucose ...of palmitic acid, oleic acid, or control (cont) (PBS), before a ...
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Oleic Acid Attenuates Palmitic Acid-Induced Impairments in Mouse Blastocyst Development
... Palmitic acid (PA) and oleic acid (OA) are the most abundant saturated and monounsaturated non- esterified fatty acids, respectively, in serum. The consequences of PA and OA treatment on ...
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