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Placental Development

Altered placental development in undernourished rats: role of maternal glucocorticoids

Altered placental development in undernourished rats: role of maternal glucocorticoids

... for placental location (mid- and proximal-horns) whereas Lesage ’ s study did not control for placental ...decreased placental weight as well as placental HSD11B-2 expres- sion ...affect ...

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Shifting perspectives from “oncogenic” to oncofetal proteins; how these factors drive placental development

Shifting perspectives from “oncogenic” to oncofetal proteins; how these factors drive placental development

... differentiation. However, these cells present their own shortcomings that make them less than ideal candidates for use. These shortcomings are especially apparent when it comes to studying DNA damage and genomic ...

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The influence of the intrauterine environment on human placental development

The influence of the intrauterine environment on human placental development

... ABSTRACT Development of the human placenta is modulated heavily by the intrauterine ...trimester, development takes place in a low oxygen environment supported by histiotrophic nutrition from the ...

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Altered placental development and intrauterine growth restriction in IGF binding protein 1 transgenic mice

Altered placental development and intrauterine growth restriction in IGF binding protein 1 transgenic mice

... of placental development are altered in IGFBP-1 transgenic ...of placental morphology in IGFBP-1 trans- genic mice are reminiscent of IGF-II–deficient mice ...that placental mass is reduced in ...

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Some historical aspects of understanding placental development, structure and function

Some historical aspects of understanding placental development, structure and function

... of placental fine structure, the issue of uterine circulation in the intervillous space remained somewhat of an ...embryonic-placental development (Ramsey, 1937; 1938), a group of Carnegie ...

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Sex differences in rat placental development: from pre-implantation to late gestation

Sex differences in rat placental development: from pre-implantation to late gestation

... its development, potentially in a sexually di- morphic manner ...larger placental growth (weight) than fe- males in uncomplicated human pregnancies at term ...in placental development is most ...

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Review Article PPAR Action in Human Placental Development and Pregnancy and Its Complications

Review Article PPAR Action in Human Placental Development and Pregnancy and Its Complications

... During pregnancy crucial anatomic, physiologic, and metabolic changes challenge the mother and the fetus. The placenta is a remarkable organ that allows the mother and the fetus to adapt to the new metabolic, ...

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Glucosamine supplementation during late gestation alters placental development and increases litter size

Glucosamine supplementation during late gestation alters placental development and increases litter size

... Gilts were unilaterally hysterectomized-ovariectomized (UHO) at 160 d of age. Gilts were anesthetized with so- dium pentothal and anesthesia was maintained using fluothane. The UHO surgery involves removing one ovary and ...

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A Pluripotent Stem Cell Model of Human Placental Development.

A Pluripotent Stem Cell Model of Human Placental Development.

... trophoblast development remains ...trophoblast development within the placenta is responsible for a number of pregnancy disorders such as preeclampsia, placental accreta, infarcts, and intrauterine ...

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Estrogen regulation of placental angiogenesis and fetal ovarian development during primate pregnancy

Estrogen regulation of placental angiogenesis and fetal ovarian development during primate pregnancy

... fetal-placental development (Albrecht and Pepe, ...follicular development in the baboon was associated with expres- sion of the mRNAs and proteins for estrogen receptor (ER) α and ER β (Pepe et ...

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Development and Function of the Human Fetal Adrenal Cortex: A Key Component in the Feto-Placental Unit

Development and Function of the Human Fetal Adrenal Cortex: A Key Component in the Feto-Placental Unit

... MC2R) (244). ACTHR mRNA was detected in the HFA as early as 8 wk post-conception (9). In our previous study using in situ hybridization, ACTHR mRNA expression levels, as judged by hybridization signal intensities, were ...

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Correlation between placental location and development of preeclampsia

Correlation between placental location and development of preeclampsia

... the development of preeclampsia as per the ACOG criteria of delivery, which is BP reading more than 140/90 and urine albumin of >300 mg in 24-hour sample or 1+ on ...

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Listeria Placental Infection

Listeria Placental Infection

... primary placental cellular target of ...the placental configuration is unclear, however, because listerial abortion in ruminants is also predominantly observed in late pregnancy (7, 20) despite having a ...

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Original Article Coagulation function and placental pathology in neonates with placental abruption

Original Article Coagulation function and placental pathology in neonates with placental abruption

... the mortality and disability. To date, no study has been reported about the relationship between coagulation dysfunction and placental pathology in neonates with PA. Thus, better understanding the clinical ...

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Placental Growth Factor and Vascular Endothelial Growth Factor Receptor-2 in Human Lung Development

Placental Growth Factor and Vascular Endothelial Growth Factor Receptor-2 in Human Lung Development

... Thirty-nine subjects were included in the PlGF and VEGFR-2 immunohistochemical study. Samples were analyzed in 6 groups, as follows: 9 fetal subjects (gesta- tional age [GA]: 18.1 ⫾ 2.6 weeks; BW: 194 ⫾ 122 g), 4 preterm ...

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Population-Based Placental Weight Ratio Distributions and Determinants of Placental Weight Ratios

Population-Based Placental Weight Ratio Distributions and Determinants of Placental Weight Ratios

... The placental weight ratio (PWR) is a common proxy for the balance between fetal and placental growth, and is defined as the placental weight over the birth ...

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Accessory Placental Structures—A Review

Accessory Placental Structures—A Review

... That eCG binds to follicle-stimulating hormone (FSH) and luteinizing hormone (LH) receptors, and it is the only gonadotropin capable of binding both receptors in mammals, except equines. The eCG is secreted between the ...

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Inhibition of placental mTOR signaling provides a link between placental malaria and reduced birthweight

Inhibition of placental mTOR signaling provides a link between placental malaria and reduced birthweight

... in placental tissue obtained from women with placental malaria and in cultured PHT cells, we observed that placental malaria-associated intervillosi- tis consistently inhibited phosphorylation of ...

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EFFECTS OF OSMOTIC GRADIENTS ACROSS THE PRIMATE PLACENTAL UPON FETAL AND PLACENTAL WATER CONTENTS

EFFECTS OF OSMOTIC GRADIENTS ACROSS THE PRIMATE PLACENTAL UPON FETAL AND PLACENTAL WATER CONTENTS

... g Osmolar Load Duration of Osmotic Gradient % Total Water Fetus Placenta Estimated % TRW Fetus. Osmolar Load= mOsm of solute infused per kg of maternal weight/hr[r] ...

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Human placental transport of cimetidine

Human placental transport of cimetidine

... This study addresses the mechanism of transport of the H2-receptor antagonist, cimetidine, by the human placenta. A 4-h recycling perfusion of a single placental cotyledon of normal, term, human placenta was used. ...

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