Post Translational Modifications
Modulation of the Transcriptional Activity of Peroxisome Proliferator Activated Receptor Gamma by Protein Protein Interactions and Post Translational Modifications
... the post-translational modifications responsible for regulating the stability, nuclear-cytosolic dis- tribution, and activity of transcription ...
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PubMed Scale Event Extraction for Post Translational Modifications, Epigenetics and Protein Structural Relations
... protein post-translational modifications, reactions relating to the epigenetic control of gene expres- sion, and part-of relations between genes/proteins, their components, and ...
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Unrestrictive identification of post-translational modifications in the urine proteome without enrichment
... identify post- translational modifications in the urine proteome with- out preferential enrichment, using a mixture of 12 human urine samples (6 males and 6 ...
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Control of post-translational modifications in antithrombin during murine post-natal development by miR-200a
... Antithrombin is the main endogenous anticoagulant and, thus, its role in regulating haemostasis is absolutely essential. Indeed, complete antithrombin deficiency is in- compatible with life and partial deficiency is an ...
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Conjugative Post Translational Modifications for Pharmacological Improvement of Therapeutic Proteins [Article Retracted]
... Preselected modifications and improved properties may result in the development of new generations of biopharmaceuticals ...conjugative post-translational modifications used by pharmaceutical ...
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HIV latency reversing agents act through Tat post translational modifications
... be post-translationally modified by a variety of cellular factors at different stages of the viral life cycle ...of post-translational modifications on Tat are well characterised, it remains ...
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Event Extraction for Post Translational Modifications
... Post-translational modifications have been a fo- cus of interest in the biomedical text mining com- munity, and a number of resources and systems targeting PTM have been ...
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Analysis of tau post-translational modifications in rTg4510 mice, a model of tau pathology
... multiple post- translational modifications such as acetylation, nitration, ubi- quitination, ...tau post-translational modifications and CSF tau production are largely ...
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Post-translational modifications of Epstein Barr virus BARF1 oncogene-encoded polypeptide
... the BARF1 protein is secreted naturally as a macromolecule endowed with mitogenic activity in various cell cultures (Sall et al., 2004; de Turenne-Tessier et al., 2005). Here, our expression system was used further to ...
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Histone post-translational modifications in frontal cortex from human donors with Alzheimer’s disease
... Histone post-translational modifications (PTMs) are a key ele- ment in epigenetic regulation of gene expression and are known to be associated with the pathology of numerous ...
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Comprehensive analysis of histone post-translational modifications in mouse and human male germ cells
... Histone proteins are a key component of chroma- tin and act as the structural unit for packaging of DNA. An octamer of two copies each of the four core histones (H2A, H2B, H3, and H4) forms the fundamental unit of ...
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Studies of protein post translational modifications using high resolution tandem mass spectrometry
... protein post-translational modifications (PTMs) due to its unique features of preserving labile modifications and providing more detailed sequence information, which has been used to study ...
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Overview of the Epigenetics and Post translational Modifications (EPI) task of BioNLP Shared Task 2011
... protein post-translational modifications event types with reference to annota- tions originally created for the Protein Information Resource 3 (PIR) (Wu et ...
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A comprehensive resource for integrating and displaying protein post translational modifications
... Findings: dbPTM (version 1.0), which was developed previously, aimed on a comprehensive collection of protein post-translational modifications. In this update version (dbPTM2.0), we developed a PTM ...
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Modulation of nucleosomal DNA accessibility via charge-altering post-translational modifications in histone core
... Charge-altering post-translational modifications (PTM) in the globular histone core are one such mechanism that is beginning to ...Charge-altering post-translational ...
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Developmentally arrested Austrofundulus limnaeus embryos have changes in post translational modifications of histone H3
... H3 post-translational modifications are extensively studied because of their impact on chromatin structure and function and their central role in epigenetic ...
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A comprehensive catalog of post-translational modifications of Drosophila melanogaster HOX protein, Sex combs reduced
... During formation of the anterior-posterior axis, Homeotic selector (HOX) proteins determine the identity of Drosophila body segments. HOX proteins are transcription factors that regulate gene expression during ...
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Sub cellular localization and post translational modifications of the Plasmodium yoelii enolase suggest moonlighting functions
... P. yoelii has a single gene for enolase. Observation of five different isoforms (pI~5.9, 6.1, 6.3, 6.5 and 6.7) suggests that four of these variants arose due to post-translational modifications. ...
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The Role of Hypoxia-Inducible Factor Post- Translational Modifications in Regulating its Localisation, Stability and Activity
... cysteine modifications together with non-canonical cysteine ...how post-translational modifications are critical steps for regulating HIF-α activity and ...
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Proteomic analysis reveals APC dependent post translational modifications and identifies a novel regulator of β catenin
... Wnt signaling generates patterns in all embryos, from flies to humans, and controls cell fate, proliferation and metabolic homeostasis. Inappropriate Wnt pathway activation results in diseases, including colorectal ...
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