protein interaction
Domain-Based Predictive Models for Protein-Protein Interaction Prediction
... predicting protein interactions us- ing domain information are developed and preliminary re- sults have demonstrated their feasibility [26, ...that protein-protein interactions are the results of ...
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Identifying and Characterizing circRNA-Protein Interaction
... modulate protein-protein ...circRNA-protein interaction, and reveal a dynamic model of the interaction in various tissues, development stages and physiological ...
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Systematic Protein-Protein Interaction and Pathway Analyses in the Idiopathic Inflammatory Myopathies
... explored. Protein-protein interaction (PPI) analyses have been performed in a number of complex diseases, including breast cancer, schizophrenia and mul- tiple sclerosis ...
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Reciprocal Perspective for Improved Protein-Protein Interaction Prediction
... All protein-protein interaction (PPI) predictors require the determination of an operational decision threshold when differentiating positive PPIs from ...all protein pairs, given the inherent ...
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Evolution of protein-protein interaction networks in yeast
... of protein-protein and genetic interaction networks has been rising in recent years, but the lack of large-scale high quality comparative datasets has acted as a ...predicted protein- ...
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High throughput protein-protein interaction data: clues for the architecture of protein complexes
... TATA-binding protein and other transcrip- tion factors [34,35] It has three distinct functional modules [26,28,35,36] along with other associated pro- ...put protein-protein interaction ...
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CoreAlign: Core based Global Alignment for Protein Protein Interaction Networks
... Nowadays, the real-world phenomenon of binding proteins to each other plays a powerful roll in configuring how cells work together to perform various functions. This progress helps in disease and drug discovery and gives ...
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A Meta-Heuristic Approach to Predict Protein-Protein Interaction Network
... predicted protein interactions are compared with the protein interaction data of BioGrid (July 2013) ...non-interacting protein pair by randomly pairing the proteins and removing those pairs ...
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Construction and analysis of protein-protein interaction network associated with human sperm-egg interaction
... constructing protein interaction networks, utilizing genomic and protein sequence information contain a study of the absence or presence of genes in associated species, co-occurrence of sequence ...
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Construction and Analysis of Tissue-Specific Protein-Protein Interaction Networks in Humans
... Studying Protein- Protein Interaction Networks (PINs) on a genome-scale has become possible through advances in high-throughput experimental ...of interaction data for several species ...
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DIFFERENT APPROACHES FOR STUDYING PROTEIN PROTEIN INTERACTION AND ANALYSIS
... in protein and protein networking databases gives the first insight to study such macromolecular interactions paving the way for their in-vitro and in-vivo ...the protein-protein ...
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Unified Alignment of Protein-Protein Interaction Networks
... present a comprehensive comparison of network aligners and find that HUBALIGN, L-GRAAL and NATALIE are the best performing, as they regularly produce the most topologically and biologically coherent alignments. ...
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A fast approach to global alignment of protein protein interaction networks
... In this paper, we focus on the problem of network alignment. This problem aims to quantify the similarity of two given graphs, resulting in the mapping of nodes from one graph to the other, along with the induced edge ...
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Detecting Protein Complexes by an Improved Affinity Propagation Algorithm in Protein-Protein Interaction Networks
... of protein complexes in protein-protein interaction (PPI) networks is important in understanding cellular ...discover protein complexes with high precision by compared with the AP, MCL, ...
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Fitting a geometric graph to a protein-protein interaction network
... for protein–protein interaction (PPI) networks is a fundamental ...PPI interaction data and embeds proteins into a low-dimensional Euclidean space, under the premise that connectivity ...
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Algorithmic approaches to protein-protein interaction site prediction
... on protein surfaces mediate virtually all biological activities, and their identification holds promise for disease treatment and drug ...modern protein-protein interaction site (PPIS) ...
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IDDI: integrated domain-domain interaction and protein interaction analysis system
... p53 protein. Interacting partners for p53 can be searched using protein search and the list of interacting partners are subdivided by domain ...the interaction mechanism of both domains for the ...
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Ontology integration to identify protein complex in protein interaction networks
... of protein complexes is useful to explain certain biological progress and to pre- dict functions of ...identify protein complexes based on the new large weighted protein interaction ...
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Prediction and characterization of protein-protein interaction networks in swine
... a protein binding a protein at the same ...the protein interaction of pig. If a porcine protein matches with one motif group, and another protein matches with another motif group ...
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Protein-protein interaction databases: keeping up with growing interactomes
... PPI databases have improved greatly over the past couple of years, and important issues, such as data exchange, are being currently addressed by some of the databases described here. An important step towards increasing ...
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