protein palmitoylation
Global Analysis of Protein Palmitoylation in African Trypanosomes
... If palmitoylation is truly essential for ...calflagin palmitoylation and flagellar traf- ficking, there are surely different levels of inhibition achieved by each construct, so that incomplete inhibition of ...
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Impact of Protein Palmitoylation on the Virulence Potential of Cryptococcus neoformans
... Ras1 protein palmitoylation is essential for growth at high temperature but is dispensable for sexual ...Ras1 palmitoylation is also required for localization of this pro- tein on the plasma ...of ...
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Analysis of Protein Palmitoylation Reveals a Pervasive Role in Plasmodium Development and Pathogenesis
... proteins. Palmitoylation is a PTM in which cysteine residues undergo a reversible lipid modification, which can regulate target proteins in diverse ...palmitoyl protein purification appro- aches and ...
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Assaying protein palmitoylation in plants
... beads protein samples are separated by SDS-PAGE and the protein of interest (POI) can be assayed for S-acylation by western blot using an anti-POI ...S-acylated protein assayed by this method is ...
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SARS-CoV envelope protein palmitoylation or nucleocapid association is not required for promoting virus-like particle production
... of palmitoylation modi- fication can markedly decrease SARS-CoV E membrane association [16] and MHV E stability ...cysteines-the palmitoylation targets in MHV E can reduce virus yields, implying their ...
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Palmitoylation of the Autographa californica Multicapsid Nucleopolyhedrovirus Envelope Glycoprotein GP64: Mapping, Functional Studies, and Lipid Rafts
... HA protein is palmitoylated at three con- served cysteine residues located at the C-terminal end of the transmembrane domain and in the cytoplasmic domain ...(40). Palmitoylation at all three cysteine ...
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<p>Androgen upregulates the palmitoylation of eIF3L in human prostate LNCaP cells</p>
... of protein palmitoylation hasten the discovery of novel palmitoylated proteins and elucidate their biological ...of protein palmitoylation under different physiological or pathological ...the ...
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Intracellular activation of EGFR by fatty acid synthase dependent palmitoylation
... Protein palmitoylation is catalyzed by a class of enzymes known as PATs, which transfer the palmitoyl group of palmitoyl-CoA to the SH group of cysteine residue of a target ...
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Palmitoylation of MIR2 Is Required for Its Function
... (A) Palmitoylation of MIR1 or MIR2 was detected by a biotin switch assay where protein palmitoylation is replaced with ...of protein were loaded in each ...The palmitoylation status of ...
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Subcellular Localization Directs Signaling Specificity of the Cryptococcus neoformans Ras1 Protein
... process, protein palmitoylation is a regulated and reversible ...that palmitoylation of ...this protein to the ...not palmitoylation, is required for ...
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Regulatory Role of Free Fatty Acids (FFAs)—Palmitoylation and Myristoylation
... This palmitoylation process enhances the surface hydrophobicity and membrane affinity of protein substrates and plays important roles in modulating proteins’ trafficking, stability, and sorting ...etc. ...
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Fatty Acid Synthase Promotes the Palmitoylation of Chikungunya Virus nsP1
... Protein palmitoylation is mediated by PATs and protein thioesterases ...the palmitoylation of nsP1. ZDHHC2 has been involved in the palmitoylation of postsynaptic density protein ...
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Effects of Palmitoylation of Replicase Protein nsP1 on Alphavirus Infection
... the palmitoylation site of ...detect palmitoylation of the proteins of interest, the transfected cells were labeled with 60 Ci of [ 3 H]palmitate between 2 and 4 h posttransfection and treated as described ...
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Palmitoylation Plays a Role in Targeting Vac8p to Specific Membrane Subdomains
... The fact that Vac8p is palmitoylated raises the possibility that vacuole microdomains may exist and, furthermore, may share common properties with the better character- ized plasma membrane microdomains, specifically ...
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Role of post translational modifications : glycosylation and palmitoylation in Toxoplasma gondii
... anonymous protein (TRAP) of Plasmodium ...This protein is found in a complex with an atypical myosin light chain [4] and two accessory proteins, GAP45 and the integral membrane glycoprotein GAP50 [5], of ...
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LMP2A Does Not Require Palmitoylation To Localize to Buoyant Complexes or for Function
... targeted green fluorescent protein (GFP) expression construct and was kindly provided by William Rodgers (33). HA-conjugated ubiquitin (HA-Ub) was also described previously (40). pDsRed1-N1 was used for red ...
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A systematic study of palmitoylation using the model organism Caenorhabditis elegans
... Protein PREDICTED: coiled-coil and C2 domain-containing protein 2A-like T-complex protein 1 subunit β cell division control protein 42 isoform 1 centrin 4 chromodomain helicase DNA-bindi[r] ...
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Interactions between Melanin Enzymes and Their Atypical Recruitment to the Secretory Pathway by Palmitoylation
... No palmitoylation signal was detected for our negative control, Mvp1 ...our palmitoylation pro- filing (see Table ...recovered protein in the palmitoylated pool versus total protein for the ...
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The Regulation Of Egfr Signaling And Kras Tumorigenesis By Receptor Palmitoylation
... The palmitoyltransferase DHHC20 is expressed in multiple human breast and lung cancer cell lines and was found to suppress metastatic behavior in melanoma cells (Figure S1) (Wang et al., 2015). Analysis of the TCGA ...
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An investigation of modification to endothelin receptors A and B, and downstream proteins, using proteomic techniques
... and palmitoylation were recovered in ...heavy palmitoylation on stimulation of the ...1 palmitoylation and 2 phosphorylations was partially sequenced, confirming one of the phosphorylations to be at ...
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