Range restriction
Host Range Restriction of Insect-Specific Flaviviruses Occurs at Several Levels of the Viral Life Cycle
... Establishment of a NIEV reverse genetics system. As a prerequisite to analysis to determine at which level(s) the vertebrate host range restriction of NIEV occurs, we established a NIEV reverse genetics ...
15
The Role of Influenza A Virus Hemagglutinin Residues 226 and 228 in Receptor Specificity and Host Range Restriction
... ever, those of human viruses display distinct variability (12). In particular, the residues at positions 138, 190, 194, 225, 226, and 228 are highly conserved in the avian RBS, whereas human HAs harbor substitutions at ...
6
Influenza Virus Sequence Feature Variant Type Analysis: Evidence of a Role for NS1 in Influenza Virus Host Range Restriction
... Host range distribution of NS1 ...host range constraints has been well studied, we chose to examine the nonstructural NS1 protein to determine the extent to which it may contribute to host range ...
10
Determinants of the Host Range Restriction of Replication of Bovine Parainfluenza Virus Type 3 in Rhesus Monkeys Are Polygenic
... host range attenuation phenotype of BPIV3 by exchanging each open reading frame (ORF) of a recombinant wild-type HPIV3 with the analogous ORF from BPIV3, with the caveats that the multiple ORFs of the P gene were ...
8
Analysis of Host Range Restriction Determinants in the Rabbit Model: Comparison of Homologous and Heterologous Rotavirus Infections
... host range restriction of rotavirus ...host range restriction in rabbits, we evaluated infection in rotavirus antibody-free rabbits inoculated orally with two P[14] HRVs, PA169 (G6) and ...
11
Correcting the predictive validity of a selection test for the effect of indirect range restriction
... Correlations derived from the subgroup of selected ap- plicants are often simply reported as indicators of pre- dictive validity without correcting for the effects of multiple selection variables and range ...
10
Eilat Virus Host Range Restriction Is Present at Multiple Levels of the Virus Life Cycle
... Host range restriction at entry level in vertebrate cell ...host range restriction is manifested at the entry level, cell lines representing various alphavirus verte- brate hosts were infected ...
15
Human Host Range Restriction of the Vaccinia Virus C7/K1 Double Deletion Mutant Is Mediated by an Atypical Mode of Translation Inhibition
... The interferon sensitivity of C7/K1 mutant replication in human Huh7 cells suggests a role for one or more interferon-stimulated genes (ISGs) (13). Screening of a library of more than 350 ISGs identified ...
18
Analysis of wild-derived mice for Fv-1 and Fv-2 murine leukemia virus restriction loci: a novel wild mouse Fv-1 allele responsible for lack of host range restriction.
... None of the wild mice showed the Fv-JT or Fv-1b restriction patterns characteristic of most inbred strains, several mice resembled the few inbred strains carrying Fv-1n1, and most differ[r] ...
5
Host range restriction of vaccinia virus in Chinese hamster ovary cells: relationship to shutoff of protein synthesis.
... Moreover, that viral RNA synthesis is required for shutoff the CHO cell line is not characteristic of Chinese of host polypeptide synthesis 1, 2, whereas hamster cells in general, becaus[r] ...
8
Selective host range restriction of goat cells for recombinant murine leukemia virus and feline leukemia virus type A.
... Based on host range, the murine leukemia virus MuLV system has the following four distinct, identifiable env genespecified subgroups: the ecotropic MuLV's, which can grow only in mouse a[r] ...
5
Murine rotavirus genes encoding outer capsid proteins VP4 and VP7 are not major determinants of host range restriction and virulence.
... We used an in vivo reassortment strategy to create a library of reassortant rotaviruses derived from the coinfection of mouse enterocytes with a virulent homologous murine rotavirus EDIM[r] ...
8
Investigation of Influenza Virus Polymerase Activity in Pig Cells
... host range restriction and adaptation to a new species is not fully ...host range restric- tion is exerted in the nucleus of the infected cell, where the viral ribonucleoproteins (vRNPs) must ...
11
Use of single gene reassortant viruses to study the role of avian influenza A virus genes in attenuation of wild type human influenza A virus for squirrel monkeys and adult human volunteers
... To identify the avian influenza A virus genes that specify the attenuation and host range restriction of avian-human ah influenza A reassortant viruses referred to as ah reassortants, we[r] ...
8
Identification of Restriction Factors by Human Genome Wide RNA Interference Screening of Viral Host Range Mutants Exemplified by Discovery of SAMD9 and WDR6 as Inhibitors of the Vaccinia Virus K1L−C7L− Mutant
... One or more homologs of the C7 protein are encoded by most poxvirus genera, although they are only 20 to 30% identical and share no recognizable motif (13). Myxoma virus carries genes en- coding three tandem C7 homologs, ...
10
Aguinisetal2016.pdf
... error, range restriction, and unequal sample sizes across moderator-based subgroups; insufficient statistical power; the artificial categorization of continuous variables; assumed negative consequences of ...
21
The Self Calibration Method for Multiple Systems at the CHARA Array
... skewness in mixed areas 1 and 2 is shown in Appendix E for sample sizes of 60 and 120, ranging from 0.408 to 0.766, thus it indicated that a degree of negative skewness happened in mixed areas 1 and 2 after truncation ...
114
Mucosal Immunization of Rhesus Monkeys against Respiratory Syncytial Virus Subgroups A and B and Human Parainfluenza Virus Type 3 by Using a Live cDNA-Derived Vaccine Based on a Host Range-Attenuated Bovine Parainfluenza Virus Type 3 Vector Backbone
... host range restriction (1, 2). The view that host range restric- tion is based on a large number of sequence differences involv- ing many genomic loci would provide an explanation for the observed ...
11
Canine parvovirus host range is determined by the specific conformation of an additional region of the capsid.
... The results show that specific conformations of the shoulder region are necessary for CPV to retain the ability to infect canine cells. This conclusion is supported by our finding that changing residue 299, 300, or 301 ...
9
Free Range VHDL: The No-frills Guide to Writing Powerful Code for Your Digital Implementations - Free Computer, Programming, Mathematics, Technical Books, Lecture Notes and Tutorials
... iterations the loop needs to perform. In this case, the loop stops iterating when the terms stated in the condition clause are not met. Using these loops in this manner constitutes a goo[r] ...
194