RING finger protein
Original Article Downregulation of ring-finger protein 43 in glioma associates with poor prognosis
... Abstract: Ring-finger protein 43 (RNF43) has been identified as a RING-type E3 ubiquitin ligase. The overexpres- sion of RNF43 results in a significant enhancement of cell growth, and ...
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<p>RING Finger Protein 38 Mediates LIM Domain Binding 1 Degradation and Regulates Cell Growth in Colorectal Cancer</p>
... other RING fi nger family proteins RNF6 and RNF38 had similar effects in mediating degradation of LDB1, but it was not further investigated in the follow-up of the ...
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Ectromelia virus RING finger protein is localized in virus factories and is required for virus replication in macrophages.
... phages were stained with Mac-1 (clone M1/70; kindly supplied by Kevin Holmes, National Institutes of Health, Bethesda, Md.) or F4/80 (clone CLA3-1; Bio- Source, Camarillo, Calif.), both of which were rat monoclonal ...
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Neuronal RING finger protein 11 (RNF11) regulates canonical NF-κB signaling
... ubiquitin-editing protein complex is responsible for deubi- quination of K63 ubiquitin linkage on receptor interacting protein 1 (RIP1) and attachment of K48 ubiquitin linkage to RIP1, which thereby ...
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Porcine RING Finger Protein 114 Inhibits Classical Swine Fever Virus Replication via K27-Linked Polyubiquitination of Viral NS4B
... pRNF114 protein belongs to the RING-UIM family, containing a RING domain ...pRNF114 RING domain mutant plasmid, pGST-pRNF114(C64/ 67A), in which the cysteines (C) at positions 64 and 67 on the ...
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Angelman syndrome: review of clinical and molecular aspects
... makorin ring finger protein 3; NDN, necdin; MAGEL2, melanoma-associated antigen-like 2; SNURF-SNRPN, small nuclear ribonucleoprotein polypeptide N upstream reading frame; PwS-iC, Prader–willi ...
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Ubiquitin Ligase Activities of Bombyx mori Nucleopolyhedrovirus RING Finger Proteins
... of protein in ND10 (4, 7, 27). A RING finger protein of herpesvirus 1, ICP0, also exhibits ND10 dispersing activity ...host protein(s) are transported to and from specific ND10 sites in ...
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Stealing the spotlight: CUL4-DDB1 ubiquitin ligase docks WD40-repeat proteins to destroy
... suppressor protein p53, which mediates cell cycle arrest or apoptosis in the face of genotoxic stress ...p53 protein levels are kept low through proteolysis, and the best characterized pathway for p53 ...
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Plasma from septic shock patients induces loss of muscle protein
... Results: Myosin content was approximately 25% lower in myotubes exposed to plasma from septic shock patients than in myotubes exposed to plasma from controls (P < 0.01). Furthermore, patient plasma increased ...
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Herpes Simplex Virus Type 1 Immediate-Early Protein ICP0 and Its Isolated RING Finger Domain Act as Ubiquitin E3 Ligases In Vitro
... a RING finger protein can be correlated with an interaction with the cognate E2 enzyme in vitro and/or in yeast two-hybrid ...ICP0 RING finger ...this protein either ...
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A phase ΙI study of five peptides combination with oxaliplatin based chemotherapy as a first line therapy for advanced colorectal cancer (FXV study)
... (ring finger protein 43) [8], 34 kDa translocase of the outer mitochondrial membrane (TOMM34) [9], and KOC1 (IMP-3; IGF-II mRNA binding protein 3) [10], as targets for the development of ...
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Characterization of the Arenavirus RING Finger Z Protein Regions Required for Z-Mediated Inhibition of Viral RNA Synthesis
... small RING finger protein called ...Z protein in the arenavirus life cycle is at present poorly ...structural protein of the virion and also suggested that Z might be the arenavirus ...
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Epigenetic reprogramming in mouse pre implantation development and primordial germ cells
... Fig. 4. Potential chemical pathways for active DNA demethylation. (A) Direct excision of 5mC (orange) by a 5mC glycosylase followed by repair via the base excision repair (BER) pathway (green and pink), as occurs in ...
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Drosophila Male-Specific Lethal-4 Protein: Structure/Function Analysis and Dependence on MSL-1 for Chromosome Association
... How- ever, the RING finger deletion mutant protein fails to bind the X chromosome in transgenic females or com- plement mZ-2 mutant males (data not shown), sug- gesting t[r] ...
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Precise assembly of ring part with optimized hollowed finger
... The finger design approach for realizing the handling an object including assembly have been studied long ...triangular finger tips, their hand can grasp a small object robustly at a unique position of the ...
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The MDM2 Oncoprotein Binds Specifically to RNA through its RING Finger Domain
... The MDM2 protein was initially tested to deter- mine if it was capable of binding to RNA because of the presence of the central zinc finger and C-terminal RING finger domains in the prot[r] ...
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Congruency of body related information induces somatosensory reorganization
... the ring and middle fingers might have already induced an expansion of their somatotopic representations in SI, resistant to the following top-down modulation projected off- ...
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A Pre-Immediate-Early Role for Tegument ICP0 in the Proteasome-Dependent Entry of Herpes Simplex Virus
... The RING finger mediates ND10 dissociation, which is thought to facilitate HSV gene expression (24, ...a RING finger-dependent manner (23) and is required for the sequestration of proteasomal ...
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A preliminary investigation assessing the viability of classifying hand postures in seniors
... the finger pinching (see highlighted boxes in Figure ...(ring finger pinching in prona- tion position) was confused with class 6 (middle finger pinching in pronation position) and class 14 ...
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Potential role of pre- and postnatal testosterone levels in attention-deficit/hyperactivity disorder: is there a sex difference?
... index finger (2D) to that of the right ring finger (4D) (2D/4D ratio) served as a surrogate of prenatal T exposure, and postnatal T was determined using salivary T ...
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