Ring finger protein 4 (RNF4)
Herpes Simplex Virus Type 1 Immediate-Early Protein ICP0 and Its Isolated RING Finger Domain Act as Ubiquitin E3 Ligases In Vitro
... formation of colocalizing conjugated ubiquitin in both infected and transfected cells (4) and that cytoplasmic ICP0 structures formed after high-level expression become associated with pro- teasomes after ...
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Original Article Downregulation of ring-finger protein 43 in glioma associates with poor prognosis
... Kaplan-Meier survival analysis was used to demonstrate the prognostic factors of glioma patients’ survival. Such as age (< 50 y or ≥ 50 y), WHO grade [low grade (grade I and II) or high grade (grade III and IV)], ...
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Neuronal RING finger protein 11 (RNF11) regulates canonical NF-κB signaling
... NF-κB responds to a diverse series of inflammatory activators, including ultraviolet light, double-stranded RNA, cytokines, vasoactive peptides and viral oncogenes [58]. Stimulation of the NF-κB signaling pathway causes ...
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<p>RING Finger Protein 38 Mediates LIM Domain Binding 1 Degradation and Regulates Cell Growth in Colorectal Cancer</p>
... all, protein ubiquitination is closely associated with the occurrence and development of ...cells. 4 Among them, the disorder of protein ubiquitination components is closely related to the occurrence ...
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Porcine RING Finger Protein 114 Inhibits Classical Swine Fever Virus Replication via K27-Linked Polyubiquitination of Viral NS4B
... FIG 4 The E3 ligase activity of pRNF114 is essential for its anti-CSFV activity. (A) Schematic structure of pRNF114 and pRNF114(C64/67A). ‘‘X’’ indicates that the cysteine residues at positions 64 and 67 on ...
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A novel RING finger in the C-terminal domain of the coatomer protein α-COP
... coat protein I (COPI) complex, which coats the vesicles involved in retrograde transport of proteins from the Golgi apparatus to the endoplasmic reticulum (ER), and in intra-Golgi protein trafficking, ...
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Characterization of the Arenavirus RING Finger Z Protein Regions Required for Z-Mediated Inhibition of Viral RNA Synthesis
... in protein size, the same overall structure is also seen in other arenavirus Z pro- ...(Fig. 4) may reflect the lower amino acid identity (43%) between the RDs of ARM ...
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Ubiquitin Ligase Activities of Bombyx mori Nucleopolyhedrovirus RING Finger Proteins
... protein remained (lane 6). Significant amounts of MBP-IE2 were also shifted into molecular-mass ladders (lane 10). How- ever, it was difficult to determine whether the other proteins contain ubiquitination ...
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The Zinc RING Finger of Bovine Herpesvirus 1-Encoded bICP0 Protein Is Crucial for Viral Replication and Virulence
... at 4°C for 15 min, and then centrifuged at 12,000 rpm at 4°C for 15 ...min. Protein concentrations were then determined by the Bradford assay (Bio- Rad), and the lysate was boiled in sodium dodecyl ...
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Drosophila Male-Specific Lethal-4 Protein: Structure/Function Analysis and Dependence on MSL-1 for Chromosome Association
... How- ever, the RING finger deletion mutant protein fails to bind the X chromosome in transgenic females or com- plement mZ-2 mutant males (data not shown), sug- gesting t[r] ...
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Angelman syndrome: review of clinical and molecular aspects
... In a cohort of AS patients participating in a natural history study conducted as part of the Rare Diseases Clini- cal Research Network, the distribution of molecular diag- noses among 286 patients was as follows: 31.1% ...
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Precise assembly of ring part with optimized hollowed finger
... Passive assembly methods have been studied since the 1980s. As a representative research of a passive assem- bly method, Whitney proposed Jamming diagram, which represents a successful condition in peg-in-hole task [1]. ...
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A practical person authentication system using second minor finger knuckles for door security
... on finger knuckle recog- nition under practical situations. Kumar et al. [4] have proposed a finger knuckle recognition algorithm using multiple patterns acquired from the index, middle, ring, ...
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Epigenetic reprogramming in mouse pre implantation development and primordial germ cells
... Fig. 4, Table 1) can convert 5mCs to thymines by deamination, creating T:G mismatches that might then become targets of thymine glycosylases (see Glossary, Box 2), such as MBD4 (methyl CpG binding domain ...
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RNF4-mediated SUMOylation is essential for NDRG2 suppression of lung adenocarcinoma
... another. RNF4 is a SUMO-targeted E3 ubiquitin ligase with a pivotal function in the DNA damage response (DDR) ...[28]. RNF4 is also required for homologous recombination, indicating that balanced ...
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The Poxviral RING Protein p28 Is a Ubiquitin Ligase That Targets Ubiquitin to Viral Replication Factories
... for 4 h, lysed in RIPA buffer, and immunoprecipitated with anti-FLAG antibody (M2; ...for 4 h, and lysed in 1% ...at 4°C, and bound proteins were eluted using 1 M imidazole in 500 mM NaCl and 20 mM ...
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A Pre-Immediate-Early Role for Tegument ICP0 in the Proteasome-Dependent Entry of Herpes Simplex Virus
... Entry of wild-type 17 ⫹ at a low MOI of 0.1 resulted in greatly reduced beta-galactosidase activity (Fig. 4D). Despite different levels of reporter gene expression, 17 ⫹ was inhibited to a similar extent by MG132 at MOIs ...
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Dermatoglyphic Digital Patterns and Pattern Intensity Index in Uterine Leiomyoma
... origin. 4, 9 These have been reported to exhibit peculiar dermatoglyphic ...patterns. 4, 9 Therefore, it was considered to find out if there is any specific dermatoglyphic pattern expressed by subjects who ...
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Congruency of body related information induces somatosensory reorganization
... same finger (e.g., middle finger) was touched on both ...one finger on the left hand being touched, while simultaneously feeling touch on that same ...ring finger). Thus in the mirror ...
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Role of Baculovirus IE2 and Its RING Finger in Cell Cycle Arrest
... the RING finger region blocked the ability of IE2 to arrest the cell ...the RING finger motif from IE2 ...the RING finger domain intact but deleting amino acids 94 to 173 ...
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