Severe Aplastic Anemia
Original Article Abnormal quantity and function of Th17 cells in patients with severe aplastic anemia combined with infection
... Severe aplastic anemia (SAA) is a serious he- matologic disease characterized by bone mar- row hematopoietic failure with a high mortality ...infection, severe anemia, or ...
8
Original Article Abnormality of lymphotoxin α in CD8+ T cells of patients with severe aplastic anemia
... Severe aplastic anemia (SAA) is a serious dis- ease that features bone marrow failure with high mortality rates. SAA is recognized as an autoimmune disease. Whose pathogenesis is that hematopoietic ...
7
Original Article Ex-vivo expansion and function identification of CD4 CD25 CD127 dim regulatory T cells in severe aplastic anemia
... Acquired severe aplastic anemia (SAA) is a rare disease characterized by severe pancytopenia and bone marrow failure. Although the exact etiology is still unknown, previous studies have shown ...
11
Original Article Activation profile of intracellular mitogen-activated protein kinases in CD8+ T lymphocytes of patients with severe aplastic anemia
... Severe aplastic anemia (SAA) is a bone marrow failure syndrome characterized by bone marrow aplasia and severe peripheral blood pancyto- ...
8
Upfront haploidentical transplant for acquired severe aplastic anemia: registry-based comparison with matched related transplant
... Aplastic anemia (AA) is a rare but potentially fatal dis- order characterized by hypocellular bone marrow and ...pancytopenia. Severe aplastic anemia (SAA) is a life- threatening type ...
10
<p>Budget Impact Of Eltrombopag As First-Line Treatment For Severe Aplastic Anemia In The United States</p>
... Background: Severe aplastic anemia (SAA) is a rare autoimmune condition resulting in low blood cell counts across lineages. Immunosuppressive therapy (IST) has demonstrated low response, toxicity, ...
9
Original Article Abnormal immunomodulatory ability on memory T cells in humans with severe aplastic anemia
... Severe aplastic anemia (SAA) is a kind of bone marrow failure mainly characterized by severe peripheral pancytopenia. Recently SAA has been recognized an immune-mediated destruc- tion of ...
11
Original Article Combined treatment of sequential intensive immunosuppressive therapy and hematopoietic growth factors in patients with severe aplastic anemia: long-term outcome of hematopoietic recovery response
... [4] Saracco P, Quarello P, Iori AP, Zecca M, Longoni D, Svahn J, Varotto S, Del VG, Dufour C, Ra- menghi U, Bacigalupo A, Locasciulli A. Cyclo- sporin A response and dependence in children with acquired aplastic ...
7
Who is the best haploidentical donor for acquired severe aplastic anemia? Experience from a multicenter study
... for aplastic anemia have shown that male recipients of transplants from female grafts showed decreased survival compared with other donor-recipient sex matches [3, 14, ...acquired severe ...
11
Value of transfusion independence in severe aplastic anemia from patients’ perspectives – a discrete choice experiment
... with severe aplastic anemia given eltrombopag has been sug- gested to be administered with immunosuppression therapy as first-line treatment ...
11
Clinical evaluation of haploidentical hematopoietic combined with human umbilical cord-derived mesenchymal stem cells in severe aplastic anemia
... very severe aplastic anemia (VSAA) were defined according to the International Aplastic Anemia Study Group [13]; patients who underwent pre- vious therapy regimens, including ...
8
Dynamics of Graft Function Measured by DNA-Technology in a Patient with Severe Aplastic Anemia and Repeated Stem Cell Transplantation
... Although bone marrow transplantation (BMT) from an HLA identical sibling is considered as treatment of choice in pediatric patients with severe aplastic anemia (SAA), a significant number of them ...
6
Effects and Predictive Factors of Immunosuppressive Therapy Combined with Umbilical Cord Blood Infusion in Patients with Severe Aplastic Anemia
... Purpose: To investigate the efficacy and safety of umbilical cord blood (UCB) infusion (UCBI) plus immunosuppressive therapy (IST) treatment in comparison to IST treatment, as well as predictive factors for clinical ...
9
Management of aplastic anemia in a woman during pregnancy: a case report
... very severe aplastic anemia died after intensive supportive and immunosuppressive treatment with methylprednisolon and CsA during and after ...
5
Recent Developments in Aplastic Anemia Therapy
... Four decades ago, when there were only a few effective treatment options, patients with severe or very severe aplastic anemia (SAA) died 1 to 2 years after diagnosis due to fatal infections ...
7
Original Article IFN-γ induces telomere attrition in aplastic anemia
... severe aplastic anemia when he was 32 years old, we detected serum IFN-γ level (69.38 pg/ml) and the telomere length (3.95 kb) after he use CsA 3 mg/ kg﹒d for one month but before ATG. After combined ...
7
Hepatitis Associated Aplastic Anemia: A review
... induced aplastic anemia improves by the administration of retroviral therapy ...the aplastic anemic secondary to hepatitis B virus infection and remission occurs from the severe ...
6
Eltrombopag for the treatment of aplastic anemia: current perspectives
... skin pigmentary anomalies, and marrow dysplasia. Absence of these features does not rule out inherited disorders, and genetic testing is recommended to exclude marrow failure syndrome, as it has critical impact on ...
11
Congenital Aplastic Anemia Caused by Mutations in the SBDS Gene: A Rare Presentation of Shwachman-Diamond Syndrome
... ABSTRACT. Clinical Findings. Aplastic anemia was diagnosed at birth for a first child from healthy noncon- sanguineous parents. The girl had hypoglycemia, which normalized within 2 months. Cow milk allergy ...
7
REVIEW ARTICLE
... : Aplastic anemia in siblings with multiple congenital anomalies (the Fan- coni type). Gasser, C., Zellweger, H., and Hotz, M.:[r] ...
11