stem-loop binding protein
Stem loop binding protein is a multifaceted cellular regulator of HIV 1 replication
... of stem-loop binding protein (SLBP), which is known to control histone ...group protein A1 (HMGA1) and viral long terminal repeat (LTR), which led to higher levels of HIV-1 genomic ...
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Cell cycle regulation of the stem loop binding protein : a key regulator in histone mRNA metabolism
... APCCdh1 is known to be regulating the expression of several S phase related proteins like Cyclin A, Skp2 and Cdc6 in G1(Petersen et al., 2000; Bashir et al., 2004; Wei et al., 2004b). It becomes active after degradation ...
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Identification of the oriI-Binding Site of Poliovirus 3C Protein by Nuclear Magnetic Resonance Spectroscopy
... 3C protein alone or in the context of precursors for specific recognition of three ...3C protein have allowed us to identify the binding sites for stmL and stmR based on residue-specific chemical ...
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Interactions of Viral Protein 3CD and Poly(rC) Binding Protein with the 5′ Untranslated Region of the Poliovirus Genome
... Interestingly, loop a and loop b contain single-stranded C- rich sequences which resemble the consensus RNA-binding site for PCBP found in several cellular mRNAs ...PCBP binding to ...
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Sequence similarity between the erythrocyte binding domain 1 of the Plasmodium vivax Duffy binding protein and the V3 loop of HIV 1 strain MN reveals binding residues for the Duffy Antigen Receptor for Chemokines
... in binding to both region II of the PvDBP and to chemokines, just as the N-terminus of CCR5 is critical for SU and chemo- kine ...C4/V3 stem of SU, and positively charged residues are implied to be ...
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Role of Stem B, Loop B, and Nucleotides next to the Primer Binding Site and the Kissing-Loop Domain in Human Immunodeficiency Virus Type 1 Replication and Genomic-RNA Dimerization
... Production and analysis of mutant viruses. COS-7 cells were transfected in parallel with wild-type plasmid pSVC21.BH10 and derived mutant plasmids, which are de- fined in Fig. 2. For PCR mutagenesis 5⬘ of the klh, the ...
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Intracellular functions of RNA-binding protein, Musashi1, in stem and cancer cells
... regulatory loop between IL-6/AKT and en- hanced phosphorylation of AKT on serine ...cancer stem cells in hepa- tocellular carcinoma are dependent to MSI1 and CD44 expression [46] ...
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Fluorescence based incision assay for human XPF ERCC1 activity identifies important elements of DNA junction recognition
... unpaired by superfamily conserved domains in order to engage the scissile phosphodiester bonds with the two metal ion catalytic site and seven highly conserved carb- oxylates (40,41). The Fen1 homologues cleave 1 nt into ...
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Distinct Poly(rC) Binding Protein KH Domain Determinants for Poliovirus Translation Initiation and Viral RNA Replication
... PV stem-loop I in concert with 3CD and another that associates with PV stem-loop IV, which are re- quired for genomic RNA replication and translation, respec- ...with stem-loop I ...
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The sequence and structure of the 3' arm of the first stem-loop of the human immunodeficiency virus type 2 trans-activation responsive region mediate Tat-2 transactivation.
... following binding of a cellular factor to the loop, the EMSA and func- tional data obtained with compensatory mutants which restore the stem suggest that sequences present in the 3 9 stem of ...
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Functional Consequences of RNA 5′-Terminal Deletions on Coxsackievirus B3 RNA Replication and Ribonucleoprotein Complex Formation
... 5= stem-loop I, which is an RNA second- ary structure required for viral RNA ...5= stem-loop I RNA forms a ribonucleoprotein complex with cellular and viral proteins involved in viral RNA ...
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Human T-cell leukemia virus type II Rex binding and activity require an intact splice donor site and a specific RNA secondary structure.
... Here, using an immunobinding assay to measure the binding of Rex protein to mutated RxRE RNAs, we show that efficient Rex binding requires a stem-bulge-loop RNA secondary structure nucle[r] ...
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Histone mRNA translation in metazoans : SLIP1 as the bridging factor between the 5' and 3' UTRs of the histone mRNA
... histone protein, H1, which brings adjacent nucleosome units ...histone protein in somatic cells is controlled at the mRNA level, mainly through post-transcriptional regulation of histone mRNA and its ...
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Overlapping Local and Long-Range RNA-RNA Interactions Modulate Dengue Virus Genome Cyclization and Replication
... (i) stem-loop A (SLA), which is the promoter for viral polymerase binding and activation (8–10); (ii) stem-loop B (SLB), which contains a sequence known as 5= upstream of the AUG region ...
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Genetic variation in vivo and proposed functional domains of the 5' noncoding region of poliovirus RNA.
... The variation seen in stem-loop G was concentrated mainly in the loop, and only few strains had nucleotide substitutions in the stem; none of these would prevent the proposed base pairin[r] ...
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The loops facing the active site of prolyl oligopeptidase are crucial components in substrate gating and specificity
... holding loop A in place enhanced catalysis, as was similarly observed in the trypsin-nicked enzyme that is cleaved in this loop ...reduce loop stabilization, increasing loop flexibility by ...
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Genetic Analysis of a Unique Human Immunodeficiency Virus Type 1 (HIV-1) with a Primer Binding Site Complementary to tRNAMet Supports a Role for U5-PBS Stem-Loop RNA Structures in Initiation of HIV-1 Reverse Transcription
... FIG. 1. RNA modeling of wild-type and mutant viral U5-PBS and U5-PBS/ tRNA. (A) The viral RNA sequence of nucleotides 1 to 230 encompassing the R-U5-PBS from the wild-type (HXB2) and mutant HXB2(Met-AC) viruses was used ...
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Lambert, Jayne (2017): Nodule inception NIN plays a dual role in the establishment of root nodule symbiosis in Lotus japonicus. Dissertation, LMU München: Fakultät für Biologie
... A negative regulatory role of NIN was demonstrated in the daphne mutant, which harbours a chromosomal translocation 7 kb upstream of NINs transcriptional start site (Yoro et al., 2014). daphne shows an increased level of ...
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A unique loop in T7 DNA polymerase mediates the binding of helicase-primase, DNA binding protein, and processivity factor
... the binding of the polymerase subunit to the helicase occurs via a highly basic, flexible domain at the C terminus of ...maintain binding to gp4 while locating the ZBD–primer ... protein, and it ...
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Recognition of the Core RNA Promoter for Minus-Strand RNA Synthesis by the Replicases of Brome Mosaic Virus andCucumber Mosaic Virus
... A stem-loop named SLC within the BMV tRNA-like structure appears to be an addition to the canonical tRNA structure ...3-nt loop (5⬘AUA3⬘) that was found to be essential for BMV RNA replication in ...
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