Subunit vaccines
Safety and Immunogenicity of Two Influenza Virus Subunit Vaccines, with or without MF59 Adjuvant, Administered to Human Immunodeficiency Virus Type 1-Seropositive and -Seronegative Adults
... virus vaccines with adjuvants, such as those containing the oil-in-water emulsion MF59, has recently opened new, interesting perspectives for the preven- tion of the disease, not only in elderly subjects but also ...
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Current Progress in Developing Subunit Vaccines against Enterotoxigenic Escherichia coli-Associated Diarrhea
... available vaccines against ETEC-associated diar- ...or subunit vaccine candidates focusing on ETEC colonization factor antigens (CFAs) and enterotoxins, the major virulence determinants of ETEC diarrhea, ...
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PLGA particulate delivery systems for subunit vaccines: linking particle properties to immunogenicity.
... effective vaccines against disease like AIDS, tuberculosis, or ...of subunit vaccines include hepatitis B, tetanus, diphtheria, pneumo- coccus and human papillomavirus (HPV) ...of subunit vac- ...
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Rational design, manufacture and evaluation of respirable TB subunit vaccines
... TB vaccines, among which subunit vaccine has drawn significant attention from researchers in this field due to its simplicity and ...for subunit vaccines since it contributes to both dosage ...
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Human Antibody Responses to Mature and Immature Forms of Viral Envelope in Respiratory Syncytial Virus Infection: Significance for Subunit Vaccines
... A number of antibodies generated during human respiratory syncytial virus (RSV) infection have been cloned by the phage library approach. Antibodies reactive with an immunodominant epitope on the F glycoprotein of this ...
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Development and Characterization of Protective Haemophilus parasuis Subunit Vaccines Based on Native Proteins with Affinity to Porcine Transferrin and Comparison with Other Subunit and Commercial Vaccines
... recombinant vaccines designed in our laboratory. Conse- quently, these two subunit vaccines cannot be recommended for an effective protection against Gla ¨sser’s ...
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Immunological and Virological Analyses of Persons Infected by Human Immunodeficiency Virus Type 1 while Participating in Trials of Recombinant gp120 Subunit Vaccines
... with subunit vaccines in animal models therefore mandate that human trials of these immunogens be carefully analyzed, particularly with respect to individuals who become infected despite ...
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Comparative Efficacy of Two Leading Candidate Ricin Toxin A Subunit Vaccines in Mice
... Following this low-dose immunization, neither the RiVax- nor the RVEc-immunized animals had detectable TNA in their sera, despite the fact that the animals were immune to the ricin chal- lenge. This phenomenon (i.e., ...
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Efficacy of inactivated whole-virus and subunit vaccines in preventing infection and disease caused by equine infectious anemia virus.
... Recent reports have described successful inactivated whole-virus vaccines that protect rhesus macaques from infection by 10 to 100 infectious doses of homologous simian immunodeficiency [r] ...
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Development of solid matrix antibody antigen (SMAA) complexes as multivalent subunit vaccines
... Initially, the traditional vaccination approach was taken using tlie whole inactivated SIV vaccines. These early vaccinations delayed or even prevented the onset of disease and successfully protected a proportion ...
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Immunodominance and Functional Activities of Antibody Responses to Inactivated West Nile Virus and Recombinant Subunit Vaccines in Mice
... existing vaccines and the rational design of new vaccine antigens and regimens ...Human vaccines are in general use against YF virus (live attenuated), JE virus (live attenuated and inactivated whole ...
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Enhancement of feline immunodeficiency virus infection after immunization with envelope glycoprotein subunit vaccines.
... The present paper describes the evaluation of the potential of different candidate FIV vaccines in a vaccination challenge experiment in SPF cats. The most striking finding was that immunization with rVV-expressed ...
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Diagnostics in animal health: How UC helps exclude and minimize impact of livestock pathogens
... novel subunit vaccines to prevent pinkeye in cattle; UC ANR specialists and advisors and the staff at the Sierra Foothill Research and Extension Center were key to the development of best management ...
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E ect of Di erent Adjuvants on the Longevity and Strength of Humoral and Cellular Immune Responses to the HCV Envelope Glycoproteins
... E1/E2-based vaccines have been shown in a preclinical setting to induce robust immune responses with generated antibodies capable of neutralizing HCV in vitro and preventing infection in non-human primate models ...
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Protective Immunity in Mice Following Immunization with the Cochleate-Based Subunit Influenza Vaccines
... In most vaccination systems, a combination of immunizing routes leads to superior immune responses and protection [18]. In contrast to most subunit vaccines, cochleates containing glyco- proteins from ...
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Studies on Porcine Circovirus Type 2 Vaccination of 5-Day-Old Piglets
... To determine if there were differences in the efficacy of one vaccine over another, two different products were used side by side in this study. Several previous studies had been performed to determine the efficacy of ...
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The Use of Analgesics during Vaccination with a Live Attenuated Yersinia pestis Vaccine Alters the Resulting Immune Response in Mice
... these vaccines and animal models must be well-characterized in the absence of analgesics initially, and the analgesics should be shown to offer measurable benefit to the animals with regard to the alleviation of ...
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Anti-Idiotype Vaccine Provides Protective Immunity Against Vibrio Harveyi in Grouper Epinephelus Coioides
... Orange-spotted grouper (Epinephelus coioides), a farmed fish species with a high commercial value, has rapidly become an important profitable agricultural product in Southeast Asia, including Taiwan and China [1]. ...
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Protective Immunity and Reduced Renal Colonization Induced by Vaccines Containing Recombinant Leptospira interrogans Outer Membrane Proteins and Flagellin Adjuvant
... leptospirosis vaccines, both for humans and animals, have failed to induce immune responses capable of conferring protection and simultaneously preventing renal coloni- ...by subunit vaccines ...
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Mueller_unc_0153D_14900.pdf
... most vaccines has been either an attenuated or killed whole ...toward subunit vaccines that utilize purified or synthetic immunogenic portions of pathogens (proteins, peptides, polysaccharides, ...
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