THE ENDOCRINE PANCREAS
Effects of secretin, pancreozymin, or gastrin on the response of the endocrine pancreas to administration of glucose or arginine in man
... Enteric infusion of hydrochloric acid, or stimulation of gastric acid secretion by betazole, presumed to cause release of endogenous secretin, led to enhancement of insulin secretion during intravenous infusion of ...
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Tyrosine hydroxylase activity in the endocrine pancreas: changes induced by short-term dietary manipulation
... pigs, suggesting that the expression of TH in the mamma- lian endocrine pancreas was not necessarily a transient phenomenon. Our study is the first to demonstrate a measurable and modulated TH activity in ...
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GABAergic system in the endocrine pancreas: a new target for diabetes treatment
... Conclusion In the past five decades, the function of GABA in the CNS has been well documented. However, the presence of a GABAer- gic system within the pancreas as a potential target for treating diabetes mellitus ...
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Role of the endocrine pancreas in the kalemic response to acute metabolic acidosis in conscious dogs
... J Clin Invest. 1985;75(3):798-808. https://doi.org/10.1172/JCI111775. Metabolic acidosis due to organic acids infusion fails to elicit hyperkalemia. Although plasma potassium levels may rise, the increase is smaller than ...
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A morphological basis for intercellular communication between alpha and beta cells in the endocrine pancreas
... Our assumption was that if morphological specializations characterizing tight and gap junctions were found between granulated and degranulated cells, their presence could be considered a[r] ...
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Improving glycemic control in critically ill patients: personalized care to mimic the endocrine pancreas
... J. Geoffrey Chase 1 , Thomas Desaive 2 , Julien Bohe 3 , Miriam Cnop 4 , Christophe De Block 5 , Jan Gunst 6 , Roman Hovorka 7 , Pierre Kalfon 8 , James Krinsley 9 , Eric Renard 10 and Jean-Charles Preiser 11* Abstract ...
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TNM staging of neoplasms of the endocrine pancreas: results from a large international cohort study
... This cohort is the largest ever published on neuroendocrine neoplasms of the pancreas listing such detailed information to our knowledge. This series results from the retrospective collection of neoplastic tissues ...
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Somatostatin blockade of acute and chronic stimuli of the endocrine pancreas and the consequences of this blockade on glucose homeostasis
... pancreatic endocrine secretion were studied by administration of a number of stimuli of either glucagon or insulin to over night fasted baboons with and without an infusion of linear ...
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Structure and function changes in the endocrine pancreas of aging rats with reference to the modulating effects of exercise and caloric restriction
... microU/ml. Morphological studies on the pancreas of these rats at the end of the year revealed enlarged, multilobulated, fibrotic islets. After collagenase digestion, the most normal-appearing islets from the ...
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Pancreas enriched miRNA refines endocrine cell differentiation
... DISCUSSION The role of Pax6 in development has been extensively studied. However, how Pax6 levels are fine-tuned in tissues is not well understood (Baulmann et al., 2002; Ding et al., 2009). Here, we discover a ...
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Zebrafish mnx1 controls cell fate choice in the developing endocrine pancreas
... vertebrate endocrine pancreas has the crucial function of maintaining blood sugar ...separate endocrine and exocrine cell lineages. Within the endocrine progenitor pool a variety of ...
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Antagonistic interactions of hedgehog, Bmp and retinoic acid signals control zebrafish endocrine pancreas development
... during pancreas development and whether its function has completely diverged between ...zebrafish endocrine pancreas development and investigate its relationship with the Bmp and retinoic acid (RA) ...
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Endocrine tumours of the pancreas: Review and recent advances
... tases. 29,30 Somatostatin receptor scintigraphy allows for whole- body assessment specific for neuroendocrine tumours that may be significant for identifying extraduodenopancreatic disease. The National Institutes of ...
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Usefulness of artificial endocrine pancreas during resection of insulinoma
... artificial endocrine pancreas (STG-22, Nikkiso ...artificial endocrine pancreas, which enabled continuous blood glucose monitoring and computer-operated glucose and insulin infusion to ...
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Abnormal endocrine pancreas function at birth in cystic fibrosis ferrets
... CF endocrine pancreas using a new CFTR-knockout ferret ...exocrine pancreas disease, progressive exocrine and endocrine pancreatic loss during the first months of life was associated with ...
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Hnf1b controls pancreas morphogenesis and the generation of Ngn3+ endocrine progenitors
... and endocrine cell development, is downstream ...+ endocrine precursors throughout ...in endocrine cell specification and suggest a mechanistic explanation of diabetes onset in individuals with ...
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Hox6 function is Necessary for Endocrine Pancreas Development in vivo and in vitro.
... Based on our recent in vivo data, we hypothesized that Hox6 genes also play a role in endocrine cell differentiation in vitro. We further hypothesized that enhancing mesodermal differentiation during in vitro ...
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Differential levels of Neurod establish zebrafish endocrine pancreas cell fates
... ectopic endocrine cells. Complete zebra fish pancreas development requires the con- tribution of cells from both the dorsal and ventral ...of endocrine cells from either of these buds requires Neurod ...
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Diabetes and other endocrine-metabolic abnormalities in the long-term follow-up of pancreas transplantation
... Abstract Pancreas transplantation (PTX) has been demonstrated to restore long-term glucose homeostasis beyond what can be achieved by intensive insulin therapy or islet ...other endocrine metabolic ...
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The L6 domain tetraspanin Tm4sf4 regulates endocrine pancreas differentiation and directed cell migration
... whereby endocrine progenitor cells initially express high levels of Tm4sf4, which is downregulated by elevated expression of ...the endocrine progenitors detach from the surrounding epithelial ducts, ...
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