The evolution of cells
Viruses and cells intertwined since the dawn of evolution
... reductive evolution, which can be supported further by the presence of a large number of enzymes in ge- nomes of giruses like various hydrolases, proteases, ki- nases, phosphatases and many others involved in ...
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The evolution of the structure of tubulin and its potential consequences for the role and function of microtubules in cells and embryos
... -tubulin evolution and function: (a) that multifunctional β -tubulins are under greater evolutionary con- straint than β -tubulins present in specialized cells or in cells with very few MT-related ...
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The ancient Virus World and evolution of cells
... come from in the first place? They would be there as long as viruses exist – suspiciously similar to the model of the virus world discussed in this paper. 3. The conservation of the hall- mark genes between prokaryotic ...
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Stochastic dynamics and the evolution of mutations in stem cells
... malignant cells appear to have a very ‘primitive origin’, implying mutations in early progenitor cells if not in the ...red cells to complement-mediated lysis) and the more sensitive flow cytometry ...
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The origin and evolution of the nervous system
... hair cells, which form an elongated microtu- bular process called the ...hair cells are surrounded by two types of support cells, which secrete the stiff cupula that ensheathes the kinocilia and ...
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The genetic control of eye development and its implications for the evolution of the various eye types
... photoreceptor cells and a lens of its own, which is characteristic for insects and other arthropods; and the mirror eye which in the case of the scallop (Pecten) uses both a lens focussing the light onto a distal ...
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Evolution of mammalian pregnancy and the origin of the decidual stromal cell
... non-ciliated cells with basal elongated nuclei and ciliated cells with large apical ...LE cells forming a homokaryon. Fusion of LE cells is also a regular feature of the non-pregnant sexual ...
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The evolution of combined molecular targeted therapies to advance the therapeutic efficacy in melanoma: a highlight of vemurafenib and cobimetinib
... Recalling the pathogenesis of cutaneous SCCs that can arise on BRAF inhibitor monotherapy and the paradoxical activation of MAPK signaling that drives cellular prolif- eration demonstrates the concept of drug dependency ...
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Neofunctionalization of Duplicated P450 Genes Drives the Evolution of Insecticide Resistance in the Brown Planthopper
... 6 cells per well were plated into 6-well plates 2 hr prior to transfection and allowed to reach 60%–70% ...of cells with PBS, cells from each well were harvested in 500 m L passive lysis buffer ...
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The evolution of a population under recombination: how to linearise the dynamics
... Haploid cells called gametes (sperm and egg cells) unite in pairs to form diploid cells called zygotes, which can then proliferate to produce individuals composed of many diploid ...Diploid ...
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Mathematical Methods for the Analysis of Polycrystal Phase Evolutions
... phase evolution of the sample on the time (or directly on the external impacts – temperature, pressure, ...unit cells, the atomic and thermal parameters, and the evolution of the di ff erent phase ...
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The evolution of embryo implantation
... trophectoderm cells penetrate the uterine ...uterine cells, while in the mouse, apoptosis of the epithelial cells facilitates penetration of trophectoderm into the endometrium (Carson et ...
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Evolution of cis regulation of the proneural genes
... upstream of ac and 31kb upstream of sc (Garcia-Garcia et al. , 1999; Gomez-Skarmeta et al. , 1995). The trans-activator Pannier binds directly to the DNA sequences of the dorsocentral en- hancer, but, through its ...
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Evolution of the organizer and the chordate body plan
... progeny cells of the upper quartet of the 8 cell stage cleaved egg (Vodicka and Gerhart, ...These cells probably rely on meso-endoderm ...vegetal cells behave autonomously because they contain all ...
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Transcriptional regulation and the evolution of development
... Some differences in the size of transcription factor gene families may correlate with anatomical evolution. If more complex develop- mental gene networks are required in order to build more complex anatomies, gene ...
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IoT: The Next Evolution of Internet
... There are many technological challenges, including, security, connectivity, compatibility and longevity standards and intelligent analysis and action. IoT has already turned i[r] ...
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<p>Repression of PCGF1 Decreases the Proliferation of Glioblastoma Cells in Association with Inactivation of c-Myc Signaling Pathway</p>
... of cells and the development of ...progenitor cells increased proliferation and neurogenesis in ...(GBM) cells, and a speci fi c inhibitor of Bmi-1, PTC-209, could signi fi cantly attenuate the ...
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Evolution of the Hox/ParaHox gene clusters
... The animals discussed so far are all bilaterally symmetrical and triploblasts, with three germ layers (echinoderm adults are pentamerally symmetrical, but develop from a bilateral larva). The taxa with only two germ ...
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Analytical tracing of the evolution of the elasto-plastic state during the bending of beams with a rectangular cross-section
... Let us now present the elasto-plastic state evolution for the case where m =2 and \|/=0.15. Because \)/]<\|/<\)/2, the plastic strains first occur between the supports at load level Ae and then at load level ...
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The evolution of sea urchin sperm bindin
... Bindin evolution driven by reinforcement would increase interspecific bindin divergence, while minimizing intraspecific bindin diver- gence, as is observed in ...
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