Thrombin generation
Implication of free fatty acids in thrombin generation and fibrinolysis in vascular inflammation in Zucker rats and evolution with aging
... increased thrombin generation was an increased fibrin network formation in MSZR as shown by thinner fibrin fibers (Wolberg, ...increased thrombin generation found in MSZR (Wolberg, ...
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New considerations on pathways involved in acute traumatic coagulopathy: the thrombin generation paradox
... increased thrombin generation after severe trauma while it should be reduced due to the inhibitory effect of aPC on FVa and FVIIIa ...decreased thrombin generation after trauma [17]. ...
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Systemic thrombin generation by glucose
... Systemic thrombin activity (F2a), i.e. thrombin protected and transported by 2- macroglobulin, is a new biomarker for the acti- vation state of coagulation in ...systemic thrombin generation ...
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The effects of tissue factor pathway inhibitor and anti beta 2 glycoprotein I IgG on thrombin generation
... NPP was used as the reference control in the anti-TFPI activity and TF-induced thrombin generation assays. TFPI-depleted plasma (TDP) and recombinant human TFPI (rTFPI) were purchased from American ...
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Elevated coagulation factor levels affect the tissue factor-threshold in thrombin generation
... monitored thrombin generation initiated by various concentrations of TF (0-15 pM) in FXII-deficient ...pathway-mediated thrombin formation, which would hamper data ...the thrombin ...
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Effect of sinus rhythm restoration on markers of thrombin generation in atrial fibrillation
... Ex-vivo thrombin generation potential was investi- gated by the calibrated automated thrombogram (CAT) assay, performed according to the manufac- turer’s instruction (Thrombinoscope BV, Maastricht, The ...
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Correction of microplate location effects improves performance of the thrombin generation test
... In 2010 we found that lots of IVIG products implicated in thrombotic adverse events can be evaluated with the TGT [14,15]. Mixing normal or FXI-deficient plasma with a thrombotic lot resulted in increased peak throm- bin ...
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Inhibition of thrombin generation in human plasma by phospholipid transfer protein
... plasma thrombin generation and factor XII-dependent kallikrein generation when sulfatide was used to stimulate factor XII autoactivation in ...inhibit thrombin generation in plasma ...
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The control of thrombin generation in haemoglobinopathies and other haemolytic red cell disorders in children
... of thrombin generation were discrepant in that there were significantly higher PF1+2 values compared to controls but TAT complex levels were not significantly different as the majority of the children in ...
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Thrombin generation and secretion of platelet Factor 4 during blood clotting
... and thrombin generation during the spontaneous clotting of whole blood in ...Both thrombin formation and secretion of platelet Factor 4 were detected at least 12 min before clotting (clotting time, ...
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Enzymatically oxidized phospholipids restore thrombin generation in coagulation factor deficiencies
... of thrombin generation in FVIII-deficient or anti-TFPI–sup- plemented plasma indicated that HETE-PLs can partially compensate for an absence of FVIII and bypass the hemophilic ...and thrombin ...
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The Role of Different Cell Types on Thrombin Generation and Fibrin Clot Formation and Structure
... level thrombin and fibrin generation on and near tissue factor-bearing cells at the periphery of the wound, but deficient thrombin propagation and fibrin formation into the central region of the ...
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Thrombotic risk assessment in antiphospholipid syndrome: the role of new antibody specificities and thrombin generation assay
... Antiphospholipid syndrome (APS) is an autoimmune condition characterized by the presence of antiphospholipid antibodies (aPL) in subjects presenting with thrombosis and/or pregnancy loss. The currently used ...
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The influence of Erythropoietin on platelet activation, thrombin generation and FVII/active FVII in patients with AMI
... To investigate the effect of the Epo treatment on coagula- tion and platelet activation markers plasma samples before and after completion of Epo therapy at day 3 were ana- lyzed. Concentrations of prothrombin fragment ...
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Impaired glucose metabolism is associated with increased thrombin generation potential in patients undergoing angioplasty and stenting
... peak thrombin generation potential compared to 60 age- and gender-matched healthy controls ...increased thrombin generation potential at least in part contributes to the higher risk of ...
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Four-factor prothrombin complex concentrate improves thrombin generation and prothrombin time in patients with bleeding complications related to rivaroxaban: a single-center pilot trial
... We sincerely thank the medical doctors and colleagues at the Medical University of Innsbruck, namely P. Innerhofer, M. Luger, B. Treichl, M. Joannidis, M. Ortler, B. Pfausler, A. Schiefecker, C. Reif, C. Irsara and P. ...
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Towards a standardization of thrombin generation assessment: The influence of tissue factor, platelets and phospholipids concentration on the normal values of Thrombogram-Thrombinoscope assay
... influence thrombin generation profile and they can be detected by the throm- bogram ...of thrombin genera- tion assay either in the absence or in the presence of TF since they exert a "non ...
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Implication of free fatty acids in thrombin generation and fibrinolysis in vascular inflammation in Zucker rats and evolution with aging
... Short title: Fatty acids in thrombin generation and vascular inflammation in aging.. * These authors contributed equally to this work..[r] ...
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Modelling of thrombin generation under flow in realistic left anterior descending geometries
... For the simulations under flow we calculated the parameters of TGA: the lag 266 time Tlag, the time until thrombin reaches its maximum concentration ttP, the maximum 267 concentration of[r] ...
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A simplified mathematical model for thrombin generation
... Permanent repository link: http://openaccess.city.ac.uk/13568/ Link to published version: http://dx.doi.org/10.1016/j.medengphy.2013.10.012 Copyright and reuse: City Research Online aims[r] ...
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