Time-to-event outcomes
Calculation of NNTs in RCTs with time-to-event outcomes: A literature review
... low-up time is fixed and the time to event plays no role or is ignored ...survival time data ...of time-to-event outcomes, the calculation of the number needed to treat is ...
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Model-based estimation of measures of association for time-to-event outcomes
... When time to event outcomes are present, the analysis is performed generally resorting to predicted values from Cox regression ...of time dependent covariate effects, it is not straightforward ...
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On the estimation of intracluster correlation for time-to-event outcomes in cluster randomized trials
... observed outcomes involves the removal of censored ob- servations and this will give rise to clusters of variable ...observed time-to-event ...
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Reporting of loss to follow-up information in randomised controlled trials with time-to-event outcomes: a literature survey
... Background: To assess the reporting of loss to follow-up (LTFU) information in articles on randomised controlled trials (RCTs) with time-to-event outcomes, and to assess whether discrepancies affect ...
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Assurance calculations for planning clinical trials with time-to-event outcomes
... accommodate time-to-event outcomes in clinical trials, assuming one of three analysis methods, and we have made software available for implementing our ...
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Statistical methods for adjusting estimates of treatment effectiveness for patient nonadherence in the context of time-to-event outcomes and health technology assessment: A systematic review of methodological papers
... A Comprehensive Pearl Growing technique, with citation searching and reference checking was applied across seven electronic databases to identify methodological papers for adjusting time-to-event ...
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Joint modelling of repeated measurements and time-to-event outcomes: flexible model specification and exact likelihood inference.
... and event history data, including dropout from longitu- dinal ...the time-to-event outcome, which is often unavoidable in any case when events correspond to ...
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Designs for clinical trials with time to event outcomes based on stopping guidelines for lack of benefit
... to event are assumed to be exponentially ...exponential time-to-event affects the timelines of the stages, but under proportional hazards of the treatment effect, it has no effect on the numbers of ...
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Empirical comparison of methods for analyzing multiple time-to-event outcomes in a non-inferiority trial: a breast cancer study
... failure time approach, thus limiting the generalizability of the ...failure time approach which is not without con- troversy ...each event has one hazard function [32], or using a multivariate ...
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Comparison of a time-varying covariate model and a joint model of time-to-event outcomes in the presence of measurement error and interval censoring: application to kidney transplantation
... The relationship between TAC and dnDSA is still largely unexplored due to numerous complexities. TAC trough levels, or the lowest concentration of drug in the blood prior to the next dose of medication, are mea- sured ...
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Adjusted estimates for time-to-event endpoints.
... In the analysis of retrospective data or when interpreting results from a single-arm phase II clinical trial relative to historical data, it is often of interest to show plots summarizing time-to-event ...
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Joint modelling of time-to-event and multivariate longitudinal outcomes: recent developments and issues
... single time-to-event outcome; herein referred to as univariate joint ...longitudinal outcomes and possibly multiple, recurrent or competing event ...the time to graft ...
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joineRML: a joint model and software package for time-to-event and multivariate longitudinal outcomes
... Despite the inherently obvious benefits of harnessing all data in a single model or the published research on the topic of joint models for multivariate longitu- dinal data, a recent literature review by Hickey et al. ...
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Sampling 'hard-to-reach' populations in health research: yield from a study targeting Americans living in Canada
... two outcomes: the extent to which the media responded to the media event, and the yield of potential study subjects over time in response to the media release and subsequent advertise- ...
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The effect of real time CPR feedback and post event debriefing on patient and processes focused outcomes : a cohort study : trial protocol
... post event debriefing, site 2 will implement audiovisual feedback only and site 3 will remain as a control site to measure any changes in outcome due to any other trust-wide changes in resuscitation ...
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Comparison of health state utility estimates from instrument based and vignette based methods: a case study in kidney disease
... fracture outcomes both for the acute phase (the year during which the event occurred) and chronic phase (more than 1-year after the ...an event such as a heart attack. The time horizon for the ...
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McGraw Hill Probability Demystified pdf
... In this chapter, the theory of probability is extended by using what are called the addition rules. Here one is interested in finding the probability of one event or another event occurring. In these ...
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Joint modelling of longitudinal and time-to-event data
... and time-to-event data, and the aim of the research was to develop a greater understanding of how these methods can be ...the time to an ...longitudinal outcomes, there will inevitably be ...
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Epidemiology and health outcomes associated with hyperkalemia in a primary care setting in England
... HK event. Each patient with an index HK event in the primary or secondary care setting was eli- gible to serve as a ...years), time since registration (± 4 years), and ...clinical outcomes and ...
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MEANTIME, the NewsReader Multilingual Event and Time Corpus
... cross-document event coreference (Cy- bulska and Vossen, 2014) and the corpus used for cross- document entity coreference at the Web People Search task at SemEval 2007 (Artiles et ...
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