β-Transforming Growth Factor
Transforming growth factor β stimulates nerve growth factor production in osteoarthritic synovium
... TGF- β and NGF using immunohistochemistry, and analyzed the relationship between NGF and TGFB mRNA ...TGF- β (rhTGF- β ), rhTGF- β + ALK5 inhibitor SB505124, rhTGF- β + ...
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Transforming Growth Factor – β and Glioma
... Transforming growth factor-beta (TGF-β) is a regulatory cytokine secreted by various types of cell such as stromal cell, immune cells and tumor ...
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Transforming growth factor-β pathway activity in glioblastoma
... Finally, the absence of a strong correlation between any TGF-β-related parameter and Ki-67 labeling (Table 2) indicates that stimulation of proliferation is not an important role of the TGF-β pathway in ...
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Transforming Growth Factor Β in Psoriasis: Pathogenesis and Therapy
... prominent alterations in dermal capillary vasculature~and the presence of dermal and epidermal T cells, monocytehacrophages, and polymorphonuclear leukocytes?.6 We have recently shown th[r] ...
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Expression of transforming growth factor-β (TGF-β) in chronic idiopathic cough
... produce growth factors such as TGF- and endothelin and epidermal growth fac- tor (EGF)-like growth factors when subjected to mechani- cal stress or pressure ...
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Transforming growth factor-β and abdominal aortic aneurysms
... The effects of TGF βs are mediated by binding to their receptors. Three classes of TGFβ receptor (TβR) isoforms have been characterized [26, 29]: Type I (TβRI), type II (TβRII) and type III (TβRIII) receptors. TGFβ ...
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Safety study: is there a pathologic IGF-1, PDGF and TGF-ß cytokine expression caused by adjunct BMP-7 in tibial and femoral non-union therapy?
... like growth factor 1 (IGF-1), platelet-derived growth factor AB (PDGF-AB) and transforming growth factor beta (TGF-β) were compared between patients with the gold ...
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Genetic analysis of female infertility with the effect of human bmp15 and gdf9 genes: a review
... the transforming growth factor-β (TGF- β) super family: growth differentiation factor 9 (GDF9) and bone morphogenetic protein 15 (BMP15) originates from oocytes are played ...
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Targeting Transforming Growth Factor β (TGF β) in Cancer and Non Neoplastic Diseases
... their growth-inhibitory arm while still responding to ...c-Myc, β-catenin and h-TERT occurs when TGF-β signaling is ...inactivate β-catenin, the key protein in the wnt signaling [40] ...
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Investigating the Role of Retinoblastoma Protein and Transforming Growth Factor-Beta in Growth Inhibition
... A recent study has shown that the TGF-β signaling pathway is regulated by multiple microRNAs (miRNAs) (272). A large-scale RNAi screen was performed to identify novel components and modulators of the TGF-β ...
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Transforming growth factor β signaling in uterine development and function
... Endometrial hyperplasia is a pathological condition where endometrial cells undergo excessive proliferation [123]. Categories of endometrial hyperplasia include simple hyperplasia, simple atypical hyperplasia, complex ...
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Growth differentiation factor 9 and bone morphogenetic protein 15 expression in previtellogenic oocytes and during early embryonic development of Yellow-tail Kingfish Seriola lalandi
... the transforming growth factor β super family (TGF-β), GDF9 and BMP15 ...These growth factors stimulate the proliferation of granu- lose cells, but also suppress follicle ...
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Peripheral chondrosarcoma progression is accompanied
... of growth plates in long ...the growth plate, but is reactivated when these tumours undergo malignant transformation towards secondary peripheral ...that transforming growth ...
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DHEA-induced ovarian hyperfibrosis is mediated by TGF-β signaling pathway
... of growth factors that promote fibrosis, such as mesenchymal marker vimentin, and a-smooth muscle actin (a-SMA) ...inhibits transforming growth factor (TGF- β ) type I receptor activin ...
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Regenerative Potential of Direct Adipose Tissue Stimulation: A Pilot Study on Skin Improvement
... Endothelial Growth Factor; IGF: Insulin-Like Growth Factor; HGF: Hepatocyte Growth Fac- tors; TGF-β: Transforming Growth Fac- tor; BAT: Brown Adipose Tissue; PEFS: ...
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Original Article Effects of insulin-like growth factor 2 and its receptor expressions on corneal repair
... epidermal growth factor (EGF), fibroblast growth factor-β (FGF-β), heparin-like growth factor (HGF), keratinocyte growth factor (KGF), ...
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Over-Production of Therapeutic Growth Factors for
... growth factor; protein production platform; protein packaging cell line; transforming growth factor 31.. β (TGF-β); GP2-293 cells 32.[r] ...
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Transforming growth factor β and breast cancer: Cell cycle arrest by transforming growth factor β and its disruption in cancer
... protein in many cancers, including breast, and may con- tribute to TGF-β resistance [37,80–82]. Less often, primary tumours may exhibit strong cytoplasmic p27 expression associated with poor prognosis. Cytoplasmic ...
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Tumour stromal interactions: Transforming growth factor β isoforms and hepatocyte growth factor/scatter factor in mammary gland ductal morphogenesis
... TGF- β in vivo, it is also important to appreciate that there are several extracellular controls on TGF-β function that can spatially and temporally regulate TGF- β action to allow context dependent ...
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Transforming growth factor β and breast cancer: Transforming growth factor β/SMAD signaling defects and cancer
... TGF- β signaling and various MAP-kinase path- ways are currently the subject of intense investigation, fueled by observations that factors of the TGF- β family and receptor tyrosine kinase activating ...
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