water maze test
Original Article DSTYK kinase domain ablation impaired the mice capabilities of learning and memory in water maze test
... DSTYK is reported to be widely distributed in multiple tissues of vertebrates from the devel- opmental stage to the adult [2]. Human DSTYK full-length (7.9 kb) mRNA is presented in many organs and tissues such as heart, ...
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Morris water maze test on neuroprotective effects of ethanolic extract of oyster mushroom (Pleurotus ostreatus) against neurotoxicity of mercury chloride in albino rats (Rattus norvegicus)
... memory test (morris water maze test), this was conducted in order to know the extent of spatial memory impairments caused by mercury toxicity, and also to ascertain the neuroprotective effects ...
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Rg3 enriched ginseng extract ameliorates scopolamine induced learning deficits in mice
... Ginsenoside Rg3 is not naturally present in Panax gin- seng [13] and is generated by the loss of the glucose group linked with the C-20 of ginsenoside Rc, Rd, Rb1, or Rb2 when ginseng roots are heated to a high ...
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Bis(9) (−) Meptazinol, a novel dual binding AChE inhibitor, rescues cognitive deficits and pathological changes in APP/PS1 transgenic mice
... Morris water maze test was performed including acquisition trial and probe trial, which primarily depends on the ...Morris water maze test than WT mice because of synaptic ...
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Enzyme replacement therapy for murine mucopolysaccharidosis type VII leads to improvements in behavior and auditory function
... abnormalities characteristic of a murine model of MPS VII have not been shown to be corrected by either bone marrow transplantation or gene therapy. However, intravenous injections of recombinant beta-glucuronidase ...
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L THEANINE SHOWING THE NEUROPROTECTIVE ACTIVITY AGAINST LIPOPOLYSACCHARIDE INDUCED NEUROINFLAMMATION IN MICE MODEL
... Neuroinflammation is associated with a number of neurodegenerative diseases such as Alzheimer’s disease. It is reported that lipopolysaccharide (LPS) can induce neuroinflammation and cognitive impairment. L-Theanine is ...
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Effects of acupuncture on vascular dementia (VD) animal models: a systematic review and meta analysis
... Sixteen of the included studies used different subtests of the Morris water maze test; all the studies met the inclusion criteria by using escape latency as outcome data, while two studi[r] ...
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A phenotypic and molecular characterization of the fmr1-tm1Cgr Fragile X mouse
... two-back test of working memory in which the subject must hold an image in his memory after viewing an intervening image and then perform a match to sample (Menon et ...plus water maze test in ...
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Neuroprotective effect of nicotine and simvastatin on cerebral ischemia induced cognitive impairment
... ischemia was induced by Bilateral Common Carotid Artery Occlusion (BCCAO) of rats for 30 minutes followed by reperfusion. The treatment was continued for another week after surgery. To evaluate the learning and memory ...
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TARGETING SEROTONERGIC PATHWAY FOR ANTI-AMNESIC ACTIVITY BY MORUS ALBA L.
... The present study aimed to evaluate the anti-amnesic potential of ethyl acetate soluble fraction of methanolic extract of Morus alba L (EASF). The effect of EASF of Morus alba on learning and memory was evaluated by ...
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Original Article Modulatory effects of GABA R on cognitive function of epileptic rats
... Morris water-maze test and passive avoidance performance test were used to detect the cognition of epileptic ...Morris water-maze test and passive avoidance performance ...
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Tanshinone I alleviates motor and cognitive impairments via suppressing oxidative stress in the neonatal rats after hypoxic-ischemic brain damage
... To further determine the therapeutic effects of TsI on HIBD, we treated the rats with TsI daily for 7 days and the first injection was carried out immediately after HIBD. Four weeks after HIBD, the Morris water ...
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Effects of Citalopram on Learning and Memory in the Mouse and Rat
... Data on the effects of serotonin reuptake inhibitors on learning and memory processes are not consistent. In the present study, the effects of citalopram, a very potent and completely selective inhibitor of the serotonin ...
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The Effects of Soy Extract on Spatial Learning and Memory Damage Induced by Global Ischemia in Ovariectomised Rats
... rotarod test there were no significant differences between the OVX-Ischemia, OVX- Ischemia-S 20 and OVX-Ischemia-S 60 groups when the animals were examined on days 3, 7, and 14 after ischemia (P > ...
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EVALUATION OF LEARNING AND MEMORY ENHANCING ACTIVITY OF COCCINIA GRANDIS FRUITS IN RATS
... Coccinia grandis, commonly known as ivy gourd and also called as baby water melon belongs to family Cucurbitaceae. Coccinia grandis is used by humans mostly as a food crop in several countries in Australia, Asia, ...
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Pharmacological models to appraisement of antianxiety activity in experimental animals
... Grawley introduced dark-light model or apparatus and Godwin in 1980 and later Costal in 1989 validated the black and white test box model by variation of illumination within the test box and the use of ...
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CNS ACTIVITY OF AERIAL PARTS OF HYBANTHUS ENNEASPERMUS MULL
... the test session animals were forced to swim individually in similar manner as pretest session for 6 minutes and the duration of immobility during last five minutes was ...
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Evaluation of Green Tea for Its Nootropic Activity
... Morris water maze consists of a large circular tank with a depth of 30cm, diameter 50cm. In the center a platform of 15cm having dimensions 5cm X 5cm is mounted. The pool is filled with water added ...
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EVALUTION OF ANXIOLYTIC ACTIVITY OF LEPTADENIA RETICULATA PLANT
... Hole board test: The hole-board test focuses on specific head dipping behaviors. The hole-board apparatus was an open-field with 16 equally spaced holes of 3 cm diameter in the floor. Wistar albino rats of ...
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Oxidation of Methionine 77 in Calmodulin Alters Mouse Development and Behavior
... Mignogna and Viggiano compiled a database of mouse knockouts that displayed altered motor activity [23]. They identified 46 genes that caused increased activity when deleted, two of which are well known calmodulin ...
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