[PDF] Top 20 Strong Ability of Nef-Specific CD4+ Cytotoxic T Cells To Suppress Human Immunodeficiency Virus Type 1 (HIV-1) Replication in HIV-1-Infected CD4+ T Cells and Macrophages
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Strong Ability of Nef-Specific CD4+ Cytotoxic T Cells To Suppress Human Immunodeficiency Virus Type 1 (HIV-1) Replication in HIV-1-Infected CD4+ T Cells and Macrophages
... induce CD4 T-cell responses in a genetically diverse population (1, ...two Nef CD4 ⫹ T-cell epitopes, Nef37-53 and Nef187-203, from two HIV-1-seropos- itive ...with ... See full document
10
Inhibition of Human Immunodeficiency Virus Type 1 Replication in Primary CD4+ T Lymphocytes, Monocytes, and Dendritic Cells by Cytotoxic T Lymphocytes
... of HIV-1 primary infection, mediat- ing transmission of virus from the periphery to systemic lym- phoid ...productively infected by R5 HIV-1 in vitro (14). Our finding that ... See full document
5
Efficient lysis of human immunodeficiency virus type 1-infected cells by cytotoxic T lymphocytes.
... of human immunodeficiency virus type 1 (HIV-1)-specific cytotoxic T lymphocytes (CTL) have examined their ability to recognize B-cell lines ... See full document
8
Strong Human Immunodeficiency Virus (HIV)-Specific Cytotoxic T-Lymphocyte Activity in Sydney Blood Bank Cohort Patients Infected with nef-Defective HIV Type 1
... controlling nef- defective HIV-1 strains and are therefore not required at com- paratively high levels in the SBBC or, alternatively, the lack of viral replication in the SBBC elicits lower ... See full document
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Induction of Anti-Human Immunodeficiency Virus Type 1 (HIV-1) CD8+ and CD4+ T-Cell Reactivity by Dendritic Cells Loaded with HIV-1 X4-Infected Apoptotic Cells
... the HIV-1 antigen preparations was essential for the efficient induction of anti-HIV-1 T-cell ...of T cells ...of HIV-1 peptide-treated DC enhances their ... See full document
8
Inhibition of Human Immunodeficiency Virus Type 1 gp120 Presentation to CD4 T Cells by Antibodies Specific for the CD4 Binding Domain of gp120
... against HIV-1 primary isolates, and pa- tients’ sera with high titers of these Abs do not exhibit broadly neutralizing activity (3, 8; Chien et ...during HIV infection would not be pro- tective and ... See full document
8
Mutational analysis of human immunodeficiency virus type 1 (HIV-1) accessory genes: requirement of a site in the nef gene for HIV-1 replication in activated CD4+ T cells in vitro and in vivo.
... Since HIV-1 replication is highly dependent on cell prolif- eration (63), we counted the number of activated CD4 1 T cells infected with each mutant virus or ... See full document
11
Discordance between Frequency of Human Immunodeficiency Virus Type 1 (HIV-1)-Specific Gamma Interferon-Producing CD4+ T Cells and HIV-1-Specific Lymphoproliferation in HIV-1-Infected Subjects with Active Viral Replication
... on HIV-1-specific lymphoproliferation, all 32 HIV-1-infected subjects were cat- egorized based on lymphoproliferative responses against HIV-1 p24 ...with ... See full document
12
Broad Recognition of Circulating HIV-1 by HIV-1-Specific Cytotoxic T-Lymphocytes with Strong Ability to Suppress HIV-1 Replication
... KI-889), T cells responded to SV9-5P/5P9I but not to SV9 ...been infected with wild-type and 5P mutant HIV-1, ...been infected with 5P mutant HIV-1 showed ... See full document
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Exosomes from Human Immunodeficiency Virus Type 1 (HIV-1)-Infected Cells License Quiescent CD4+ T Lymphocytes To Replicate HIV-1 through a Nef- and ADAM17-Dependent Mechanism
... from HIV-1-infected lymphocytes associ- ates with HIV-1 replication in cocultured quiescent CD4 ⴙ T ...by HIV-1- infected cells would ... See full document
11
Human Endothelial Cells Enhance Human Immunodeficiency Virus Type 1 Replication in CD4+ T Cells in a Nef-Dependent Manner In Vitro and In Vivo
... modulate HIV-1-infected T ...⫹ T cells stimulated by professional APCs express early activation markers only transiently, EC-stimulated CD8 ⫹ T cells maintain ... See full document
13
Human Immunodeficiency Virus Type 1- and Cytomegalovirus-Specific Cytotoxic T Lymphocytes Can Persist at High Frequency for Prolonged Periods in the Absence of Circulating Peripheral CD4+ T Cells
... Human immunodeficiency virus type-1 (HIV-1)-specific cy- totoxic T cells (CTL) play a central role in the control of HIV-1 ...the ... See full document
5
Patterns of Cytokine Production in Human Immunodeficiency Virus Type 1 (HIV-1)-Specific Human CD8+ T Cells after Stimulation with HIV-1-Infected CD4+ T Cells
... Although human immunodeficiency virus type 1 (HIV-1)-specific CD8 ⴙ T cells can produce various cytokines that suppress HIV-1 ... See full document
8
Differential Neutralization of Human Immunodeficiency Virus (HIV) Replication in Autologous CD4 T Cells by HIV-Specific Cytotoxic T Lymphocytes
... to T-cell exhaustion (3, 4, 33). The ability of CD8 T cells to secrete multiple cytokines has been associated with long-term nonprogressive infection but also has not been di- rectly linked to ... See full document
12
CD4-Negative Cells Bind Human Immunodeficiency Virus Type 1 and Efficiently Transfer Virus to T Cells
... with T cells during antigen presentation, it is interesting to consider how the trans- fer of virus to T cells in our study compares to previous reports of DC transfer of virus ... See full document
8
Follicular Dendritic Cells and Human Immunodeficiency Virus Type 1 Transcription in CD4+ T Cells
... other cells could also be involved. The ability to increase HIV replication is not unique to FDCs, as dendritic cells have also been shown to increase HIV production by ... See full document
9
Contact of human immunodeficiency virus type 1-infected and uninfected CD4+ T lymphocytes is highly cytolytic for both cells.
... fected cells were lysed by cultured CD4 1 T cells during 8 h of incubation, indicating that lysis initiated by the CD4 1 T cell- target cell interaction was very ... See full document
7
Few infected CD4+ T cells but a high proportion of replication-competent provirus copies in asymptomatic human immunodeficiency virus type 1 infection.
... 4 0022-538X/91/042019-05$02.00/0 Copyright © 1991, American Society for Microbiology Few Infected CD4+ T Cells but a High Proportion of ReplicationCompetent Provirus Copies in Asymptomat[r] ... See full document
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Evaluation of human immunodeficiency virus type 1 (HIV-1)-specific cytotoxic T-lymphocyte responses utilizing B-lymphoblastoid cell lines transduced with the CD4 gene and infected with HIV-1.
... The analysis of CTL responses to individual HIV-1 proteins in vaccine recipients has been complicated by the presence of high levels of vaccinia-virus-specific lytic activity which inter[r] ... See full document
10
Virus-Specific Interleukin-17-Producing CD4+ T Cells Are Detectable in Early Human Immunodeficiency Virus Type 1 Infection
... early HIV-1 infection (individuals infected for less than 1 year), which were signifi- cantly greater in frequency than for individuals with chronic HIV-1 infection or for ... See full document
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