[PDF] Top 20 A Cell Line-Based Neutralization Assay for Primary Human Immunodeficiency Virus Type 1 Isolates That Use either the CCR5 or the CXCR4 Coreceptor
Has 10000 "A Cell Line-Based Neutralization Assay for Primary Human Immunodeficiency Virus Type 1 Isolates That Use either the CCR5 or the CXCR4 Coreceptor" found on our website. Below are the top 20 most common "A Cell Line-Based Neutralization Assay for Primary Human Immunodeficiency Virus Type 1 Isolates That Use either the CCR5 or the CXCR4 Coreceptor".
A Cell Line-Based Neutralization Assay for Primary Human Immunodeficiency Virus Type 1 Isolates That Use either the CCR5 or the CXCR4 Coreceptor
... X4 isolates to the surfaces of human cells (40); presum- ably, X4 isolates are less dependent than R5 isolates on Poly- brene to overcome electrostatic repulsive ...X4 isolates. We have ... See full document
9
The CCR5 and CXCR4 Coreceptors Are Both Used by Human Immunodeficiency Virus Type 1 Primary Isolates from Subtype C
... vaccines based on neutral- izing-antibody induction, as well as therapeutic approaches based on inhibiting viral entry, might need to be designed differently for use in areas where subtype C viruses ... See full document
8
Patterns of CCR5, CXCR4, and CCR3 Usage by Envelope Glycoproteins from Human Immunodeficiency Virus Type 1 Primary Isolates
... the cell fusion assay versus the minimal activity of the corresponding HIV strains in productive infection ...the CXCR4 level in macro- phages declines dramatically during 5 days in culture (35); ... See full document
7
Inhibition of human immunodeficiency virus fusion by a monoclonal antibody to a coreceptor (CXCR4) is both cell type and virus strain dependent.
... some CXCR4 2 CD4 1 cell types (Table 2) and there- fore must use alternative coreceptors for entry into these ...several primary dual-tropic HIV-1 isolates (as well as ... See full document
5
Coreceptor Utilization by Human Immunodeficiency Virus Type 1 Is Not a Primary Determinant of Neutralization Sensitivity
... tinct isolates of HIV utilize as coreceptors different chemokine receptor ...all primary isolates of HIV in- fect primary T lymphocytes, some also infect cells of the mac- rophage lineage (31, ... See full document
5
Cytopathicity of Human Immunodeficiency Virus Type 1 Primary Isolates Depends on Coreceptor Usage and Not Patient Disease Status
... Human immunodeficiency virus type 1 (HIV-1) is known to evolve throughout the course of disease in infected individuals (25, ...clinical isolates from early and late ... See full document
6
Replicative function and neutralization sensitivity of envelope glycoproteins from primary and T-cell line-passaged human immunodeficiency virus type 1 isolates.
... HIV-1 isolates that were passaged on T-cell lines or that represent primary, clinical ...The use of the env comple- mentation system has several advantages for these ...during ... See full document
10
Primary Human Immunodeficiency Virus Type 2 (HIV-2) Isolates Infect CD4-Negative Cells via CCR5 and CXCR4: Comparison with HIV-1 and Simian Immunodeficiency Virus and Relevance to Cell Tropism In Vivo
... and CCR5. Two strains were identified that predomi- nantly use CCR5 (ALI and MLC), and two were identified that predominantly or exclusively use CXCR4 (MIL and ...SAB). ... See full document
10
Evidence for Common Structural Determinants of Human Immunodeficiency Virus Type 1 Coreceptor Activity Provided through Functional Analysis of CCR5/CXCR4 Chimeric Coreceptors
... of CXCR4 domain ...of CXCR4 domains in chimeric corecep- tors, our study is the first to demonstrate the ability of each extracellular domain to support X4 fusion and ...utilize CXCR4 in different ... See full document
12
Exclusive and Persistent Use of the Entry Coreceptor CXCR4 by Human Immunodeficiency Virus Type 1 from a Subject Homozygous for CCR5 Δ32
... major human immunodeficiency virus type 1 (HIV-1) coreceptor CCR5 (CCR5 2 / 2 ) lack functional cell surface CCR5 molecules and are relatively ... See full document
8
Primary Human Immunodeficiency Virus Type 2 (HIV-2) Isolates, Like HIV-1 Isolates, Frequently Use CCR5 but Show Promiscuity in Coreceptor Usage
... some human immuno- deficiency virus type 1 (HIV-1) isolates can be suppressed in vitro by the CC chemokines MIP-1a, MIP-1b, and RANTES (15) and the cDNA cloning of a cofactor, ... See full document
7
Preferential Use of CXCR4 by R5X4 Human Immunodeficiency Virus Type 1 Isolates for Infection of Primary Lymphocytes
... to use low levels of CCR5 in cell line-based assays (data not ...single primary isolate swarm, R5X4 variants were more constrained than R5 variants in their ability to fuse with ... See full document
7
Chemokine Coreceptor Usage by Diverse Primary Isolates of Human Immunodeficiency Virus Type 1
... isolated primary viruses by their abilities to induce syncytia in the MT-2 trans- formed T-cell line, as previously described ...of primary infection, 71 ...during primary infection ... See full document
6
Primary, syncytium-inducing human immunodeficiency virus type 1 isolates are dual-tropic and most can use either Lestr or CCR5 as coreceptors for virus entry.
... of primary syncytium-inducing (SI) human immunodeficiency virus type 1 isolates that infected several CD4 1 T-cell lines, including MT-2 and C8166, were ... See full document
6
Continued Utilization of CCR5 Coreceptor by a Newly Derived T-Cell Line-Adapted Isolate of Human Immunodeficiency Virus Type 1
... differential use of CC chemokine receptor 5 (CCR5) and CXC chemokine receptor 4 (CXCR4) may be intimately involved in the transmission and progression of human immunodeficiency ... See full document
6
Sensitive Cell Based Assay for Determination of Human Immunodeficiency Virus Type 1 Coreceptor Tropism
... The use of CCR5 antagonists in antiretroviral regimens has relied on the ability of HIV-1 tropism assays to detect viruses capable of using CXCR4 to enter the host cell (29, ... See full document
11
Neutralization Sensitivity of Human Immunodeficiency Virus Type 1 Primary Isolates to Antibodies and CD4-Based Reagents Is Independent of Coreceptor Usage
... HIV-1 primary isolates in PBMC is independent of CCR5 or CXCR4 ...of primary and TCLA isolates to neutralization by MAbs and CD4-based reagents in a standard ... See full document
10
Antibody Binding and Neutralization of Primary and T-Cell Line-Adapted Isolates of Human Immunodeficiency Virus Type 1
... mediating cell-cell fusion and recapitulate the neutralization and coreceptor phenotypes of the parent virus population (16, ...the cell surface much as on HIV ...the cell ... See full document
12
N-Linked Glycosylation of CXCR4 Masks Coreceptor Function for CCR5-Dependent Human Immunodeficiency Virus Type 1 Isolates
... expands CXCR4 coreceptor activity. The vaccinia virus-based -Gal cell fusion assay was performed to examine the non-N-linked glycosylated CXCR4 mutants in an experiment ... See full document
10
Coreceptor usage of primary human immunodeficiency virus type 1 isolates varies according to biological phenotype.
... groups based on the properties of their primary sequence, the corresponding recep- tors are named accordingly C-C or C-X-C ...utilize CXCR4 whereas envelope glycoproteins from primary ... See full document
10
Related subjects