[PDF] Top 20 Clonal analysis of CD4+/CD8+ T cells in a patient with aplastic anemia
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Clonal analysis of CD4+/CD8+ T cells in a patient with aplastic anemia
... of T cell receptor beta chain genes, suggesting clonality of these T ...cells. CD4+/CD8+ T cells clones were found to be efficiently cytotoxic towards autologous ... See full document
9
Original Article Abnormality of lymphotoxin α in CD8+ T cells of patients with severe aplastic anemia
... as T cell growth factor (TCRF), was a kind of cytokines mainly produced by activated CD4+ T cells and CD8+ T ...all T cells ... See full document
7
Regulation of human megakaryocytopoiesis An in vito analysis
... severe aplastic anemia produced significant enhancement of CFU-M-derived colony formation in ...of aplastic anemia serum. In the presence of 10% aplastic anemia serum, cultured ... See full document
10
Original Article Ex-vivo expansion and function identification of CD4 CD25 CD127 dim regulatory T cells in severe aplastic anemia
... Treg cells. Results: The Treg cells were expanded to approximately 10-fold in 1-2 weeks and retained the Treg cell phenotypic ...SAA patient can be sorted and expanded successfully in vitro, and used ... See full document
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Decreased CD8+T cell response to Epstein-Barr virus infected B cells in multiple sclerosis is not due to decreased HLA class I expression on B cells or monocytes
... Student’s t test or the Mann-Whitney rank sum test was used, according to the distribution of the ...one-way analysis of variance with Dunnett’s test for multiple comparisons was ...The ... See full document
6
Original Article Activation profile of intracellular mitogen-activated protein kinases in CD8+ T lymphocytes of patients with severe aplastic anemia
... in CD8+ Lymphocytes in SAA patients was higher than that in normal con- ...in CD8+ lymphocytes be- tween SAA patients and normal ...in CD8+ lymphocy- tes between SAA patients and normal con- ...blood ... See full document
8
Analysis of lymphocytes in patients with Plasmodium vivax malaria and its relation to the annexin A1 and IL 10
... quantification: CD4+, CD8+ and Treg cells (CD4+/CD25+/FOXP3+) and ANXA1 expression 100 separate fields of each individual smears were ... See full document
7
Antibody microarray analysis of cell surface antigens on CD4+ and CD8+ T cells from HIV+ individuals correlates with disease stages
... on CD8+ T cells, CD16 and CD56 were signifi- cantly higher for LTNP than for BDL and VIR groups, though not all detected differences reached statistical sig- nificance (p = ...of CD8+ T ... See full document
13
Clonal analysis of CD4+ T cells
... Where clonal expansions have been reported in CD8^CD45RA^ cells they are usually found within distinct subsets of ...that clonal expansions in CMV are within CD27^CD28‘ and CD27’CD28‘ ... See full document
243
CD19 CAR–T cells of defined CD4+:CD8+ composition in adult B cell ALL patients
... CAR–T cells in the event of severe ...patients, analysis of serum IL-6 and IFN-γ concentrations early after CAR–T cell infu- sion might be employed to identify patients at risk of ... See full document
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Patient derived hepatitis C virus inhibits CD4+ but not CD8+ T lymphocyte proliferation in primary T cells
... [7], cells exposed to HCV were maintained in culture in the presence of IL-2 under alternating stimu- lation with ...% cells were CD3-reactive and CD8 + T cells were evi- dently more ... See full document
11
Lymphocyte and monocyte flow cytometry immunophenotyping as a diagnostic tool in uncharacteristic inflammatory disorders
... 4-colour analysis. The following four antibodies were added to each cell tube: CD8-FITC/CD4-PE/CD3-PE-Texas Red/ HLA-DR-PE-Cy5, CD20-FITC/CD27-PE/CD19-PE- Texas Red/CD5-PE-Cy5, CD14-FITC/CD40-PE/CD3- ... See full document
9
OX40 ligand expressed by DCs costimulates NKT and CD4+ Th cell antitumor immunity in mice
... tumor cells was also observed in mice treated with AdOX40L-modi- fied DCs, whereas only minimal cytolytic activity was observed in control mice (Figure ...(LLC) cells (Figure ... See full document
10
Simultaneous inhibition of JAK and SYK kinases ameliorates chronic and destructive arthritis in mice
... of CD8 + T cells and neu- trophils (not shown) were comparable among healthy and treated ...NK cells was already observed after 6 days of treatment (not shown) and is in accordance with the ... See full document
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Divergent Kinetics of Proliferating T Cell Subsets in Simian Immunodeficiency Virus (SIV) Infection: SIV Eliminates the “First Responder” CD4+ T Cells in Primary Infection
... SIV-infected cells in tissues by in situ hybridization and multilabel confocal ...Labeled cells were visualized using horseradish alkaline phosphatase-con- jugated sheep antidigoxigenin ...mRNA-positive ... See full document
7
Nef functions in BLT mice to enhance HIV 1 replication and deplete CD4+CD8+ thymocytes
... The molecular clone, LAI (accession # K02013), is described by Peden et al. [29]. pLAINef dd was made by first removing the internal XhoI and Acc65I fragment internal to nef , treating with Klenow and religating. This ... See full document
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Peripheral blood CD4+CD25+CD127low regulatory T cells are significantly increased by tocilizumab treatment in patients with rheumatoid arthritis: increase in regulatory T cells correlates with clinical response
... mononuclear cells defined using cell surface ...peripheral T cell subsets and serum markers, composite measures of disease activity, and Health Assessment Questionnaire Disability Index score at ...(NK) ... See full document
10
Epigenome-wide association study of DNA methylation in panic disorder
... PD patient was diagnosed according to the Diagnostic and Statistical Manual of Mental Disorders, 4th Edition (DSM-IV) criteria [61] based on responses to the Mini International Neuropsychiatric Interview (MINI) ... See full document
11
Early adaptive immune activation detected in monozygotic twins with prodromal multiple sclerosis
... our t-SNE ...B cells are a cel- lular source of OCBs (33), which at least in some cases were shown to be involved in removal of debris from cells that died by prior events ... See full document
12
Lymphocyte adaptor protein LNK deficiency exacerbates hypertension and end organ inflammation
... medium supplemented with 5% FBS and stimulated with 2 μl of BD Leukocyte Activation Cocktail (ionomycin and PMA along with the Golgi inhibitor, brefeldin A) at 37°C for 5 hours. Cells were washed and stained first ... See full document
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