[PDF] Top 20 Comparison of registered and published outcomes in randomized controlled trials: a systematic review

... of trials for which a discrep- ancy was present between the registered and published primary ...report registered outcomes at various time points, we used the primary outcome ... See full document

... of systematic reviews on February 2016 (registry number: CRD 42016035872) [17, ...The systematic review was performed using MEDLINE, EMBASE, and Cochrane through February 2016 to identify all ... See full document

... Clinical Trials Registry Platform. We will use a validated randomized control trial search filter to identify studies evaluating any strategy to optimize sedation in mechanically ventilated adult ...Our ... See full document

... the systematic review (randomized controlled trials and long-term follow-up studies derived from the randomized controlled ...lower outcomes than CBT and its ... See full document

... Relevant randomized controlled studies that were published between January 2005 and March 2016 were searched in six databases: PubMed, CINAHL, EMBASE, the Cochrane Library, PsycINFO, and Web of ... See full document

... We performed a literature search in Medline, PubMed, Cochrane database, Science Direct, Ovid, and Scopus. The results were limited to full-text articles published in English. The search terms used were ... See full document

... Frequently, systematic review applies a statistical tech­ nique, so­called meta­analysis, to synthesize the outcomes of included ...their outcomes by using the ...for comparison or ... See full document

... Articles published after 1990 were selected because it appeared that the International Committee of Medical Journal Editors’ recommendation had been adopted by the relevant researchers, thus strengthening the ... See full document

... The risk of bias and methodological quality of the included studies are described in the Table 1. Randomization, baseline similarity, intention to treat ana- lysis, between group comparison and point measures were ... See full document

... All randomized controlled trials from peer reviewed journals written in English, available in full text, and matching the above selection criteria were included in order to increase the rigor of the ... See full document

... a systematic review reported according to the PRISMA-P 2015 ...checklist. Randomized controlled trials (RCTs) will be ...of Controlled Trials, ISI Web of Science and ... See full document

... Five RCTs met the inclusion criteria for the review [33–37]. Two authors were contacted to clarify questions on study design [33] and the breakout of infections by revision THA/TKA [37]. In Chiu [33], both the ... See full document

... all published domestic and international RCTs on Wenxin keli; comparable baseline test data; interventions with individual drugs and Wenxin keli doses of 9 g, three times/day; any particular course of treatment; ... See full document

... articles published before 1995 were ...cancer outcomes were achieved (Stockholm/Swedish; Dutch Total Mesorectal Excision (TME) and CRO7 trials), these were associated with deterioration in some ... See full document

... 22 trials in the present review, whereas pre- viously published reviews trying to as- sess the effectiveness of ...cluded randomized controlled trials and did not report MD of ... See full document

... of outcomes may also affect the validity of clinical trial ...the outcomes of patients who received their assigned treatment) rather than a pre-planned intention-to-treat analysis (which considers the ... See full document

... enhance the rate of tooth movement by promoting al- veolar bone remodeling [35]. The anabolic effects of supplemental vibrational therapy on bone metabolism have been long recognized [36]. Its effectiveness in promoting ... See full document

... chemopreventive agents are needed as a treatment option for oral leukoplakia lesion (OPL), especially in elderly people who may have difficulties undergoing extensive surgeries or in lesions such as proliferative ... See full document

... a systematic review of randomized controlled trials (RCT) of clinical effects of oxytocin in PTSD and trauma-related disorders was ... See full document

... However, the following limitations of our meta- analysis should be considered. First, the magnitude of in- cluded studies and participants was relatively small. Sec- ond, all of the included studies lacked of long-term ... See full document