[PDF] Top 20 Deleterious Effects of Hepatitis Delta Virus Replication on Host Cell Proliferation
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Deleterious Effects of Hepatitis Delta Virus Replication on Host Cell Proliferation
... stable cell lines or transgenic mice which continuously replicate HDV, we have been unable to observe persistent HDV replication following introduction of a ...the cell lines, though this cannot be ... See full document
5
Diverse Effects of Cyclosporine on Hepatitis C Virus Strain Replication
... genome replication by ...this replication was not due to the integration of the replicon construct into the ...the replication of HCV genome, irrespective of the presence of the structural ...days. ... See full document
11
Dissecting the Interferon-Induced Inhibition of Hepatitis C Virus Replication by Using a Novel Host Cell Line
... The Hepatitis C virus (HCV), a member of the family Flaviviridae, is a major cause of chronic liver ...the virus in a large proportion of individ- ...hepatoma cell line ...hepatoblastoma ... See full document
16
Effects of Conserved RNA Secondary Structures on Hepatitis Delta Virus Genotype I RNA Editing, Replication, and Virus Production
... Our results indicate that HDV genotype I uses an editing site that is optimized for virus production rather than suitabil- ity as a substrate for ADAR1. This conclusion is similar to that in a recent study (29), ... See full document
7
Hepatitis Delta Antigen Regulates mRNA and Antigenome RNA Levels during Hepatitis Delta Virus Replication
... Differential effects of HDAg levels on the accumulation of HDV antigenome RNA and ...divergent effects of HDAg(–) RNA on the accumulation of mRNA and full-length RNAs suggested that these RNAs might be ... See full document
16
Evolution of Hepatitis Delta Virus RNA Genome following Long-Term Replication in Cell Culture
... genome replication in order to follow the accumulation of changes that occur during ex- tended replication of the HDV genome ...HDV replication, cell cycle arrest, and cell ...per ... See full document
7
Limitations to Replication of Hepatitis Delta Virus in Avian Cells
... large delta proteins and saw no toxic effects ...toxic effects were so extensive, make us more receptive to the pos- sibility that under certain other conditions of expression in mammalian cells ... See full document
6
Development of a Novel System To Study Hepatitis Delta Virus Genome Replication
... cytotoxic effects in cultured cells (as reviewed in references 12 and ...HDV replication induced in 293-HDV cells reported here could explain a previous report where transient expression of HDV ... See full document
7
Replication of hepatitis delta virus RNA in mice after intramuscular injection of plasmid DNA.
... cular replication of HDV efficiently induced HDAg-specific humoral antibody ...vaccinia virus vectors expressing HDAg for in vitro stimulation and target cell ... See full document
5
Hepatitis B Virus Replication Induces Methylation of both Host and Viral DNA
... the host methylation machinery or through nonspe- cific methylation of host CpG islands as a result of chronic overexpression of ...Epstein-Barr virus (EBV), are maintained in their latent state in ... See full document
9
Initiation of Hepatitis Delta Virus Genome Replication
... in virus repli- cation is less clear. Attempts to achieve genome replication by transfection of cells with viral cDNAs have been successful, but only when the cDNA encodes a functional dAg-S protein ...the ... See full document
6
Hepatitis Delta Virus Replication Generates Complexes of Large Hepatitis Delta Antigen and Antigenomic RNA That Affiliate with and Alter Nuclear Domain 10
... We often observed clusters of HDAg-positive cells, suggest- ing that some cells may have undergone several divisions fol- lowing infection. Also, the RNA and L-HDAg production was lower than expected from the appearance ... See full document
8
A pseudoknot ribozyme structure is active in vivo and required for hepatitis delta virus RNA replication.
... of hepatitis delta virus (HDV) have so far been studied primarily in ...HDV replication cycle have not been ...HDV replication cycle in ... See full document
8
Characterization of the 5′ Ends for Polyadenylated RNAs Synthesized during the Replication of Hepatitis Delta Virus
... liver tissue were at nt 1630. Moreover, we obtained the same answer for RNAs from infected liver tissue and for cultured cells transfected with either a cDNA construct or an RNP assembled in vitro. (ii) The new result ... See full document
7
RNA-binding activity of hepatitis delta antigen involves two arginine-rich motifs and is required for hepatitis delta virus RNA replication.
... To determine whether either of the ARM-like sequences was involved in RNA binding, we made a series of deletion mutants starting from the C-terminal end of the middle domain M of HDAg am[r] ... See full document
7
Production of hepatitis delta virus and suppression of helper hepatitis B virus in a human hepatoma cell line.
... By transient transfection of the human hepatoma cell line HuH-7 with a plasmid, pA3HBV3.8, containing the 3.8-kb HBV DNA sequence, which is able to produce the pregenomic HBV RNA, we hav[r] ... See full document
6
Vaccinia Virus Replication I. Requirement for the Host-Cell Nucleus
... In virus-infected whole cells lanes 1-5 and enucleated cells lanes 6-10, the pattern of gene expression was identical: at 0 h primarily host proteins were labeled, at 1.5 h early vaccini[r] ... See full document
11
Transcription Factor YY1 and Its Associated Acetyltransferases CBP and p300 Interact with Hepatitis Delta Antigens and Modulate Hepatitis Delta Virus RNA Replication
... Since replication of the HDV genome depends on cellular tran- scription machinery and is modulated by RNA polymerase II, B23, and nucleolin, it raises the possibility that HDAg interacts with these nuclear ... See full document
12
Cell-Free Replication of the Hepatitis C Virus Subgenomic Replicon
... labeled replication products were eluted from an agarose gel and used as a probe for hybridization in a Northern blot which included the following RNAs ...4. Effects of actinomycin D and micrococcal ... See full document
7
Origin of Hepatitis Delta Virus mRNA
... Hepatitis delta virus (HDV) is unique relative to all known animal viruses, especially in terms of its ability to redirect host RNA polymerase(s) to transcribe its 1,679-nucleotide (nt) ... See full document
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