[PDF] Top 20 Differentiated liver cell specificity of the second enhancer of hepatitis B virus.
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Differentiated liver cell specificity of the second enhancer of hepatitis B virus.
... Second, box a-binding protein a is present in well-differentiated liver cells such as HepG2 and HuH-7 cells but not in poorly differentiated liver cells such as HA22T/VGH cells or nonliv[r] ... See full document
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The genome of hepatitis B virus contains a second enhancer: cooperation of two elements within this enhancer is required for its function.
... To determine whether enhancer II nt 1636 to 1741 stimulates the promoter activity of SPI and the SPII of HBV, the 106-bp fragment of the enhancer II was inserted downstream from the CAT [r] ... See full document
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Interaction between STAT-3 and HNF-3 Leads to the Activation of Liver-Specific Hepatitis B Virus Enhancer 1 Function
... promoting cell growth, since IL-6-mediated activation of STAT-3 is required in liver re- generation ...stimulate cell pro- liferation, because constitutively activated STAT-3 has been reported in ... See full document
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In vivo activity of the hepatitis B virus core promoter: tissue specificity and temporal regulation.
... serious liver damage in any of the mice, although a functional X protein is expressed, at least in AX16 transgenic mice ...any liver pathology, we hypothesized that this could be due to a defect in the ... See full document
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Liver cell specific targeting by the preS1 domain of hepatitis B virus surface antigen displayed on protein nanocages
... the hepatitis B virus on their surfaces, were prepared by genetic engineering ...higher specificity for human hepatocyte cell lines than other cell lines in ... See full document
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Hepatitis B virus (HBV) promoters are regulated by the HBV enhancer in a tissue-specific manner.
... The relative promoter activities in the human HepG2 liver, HeLa, and HS27 fibroblast cell lines are in the order precore > X > preS2 > preSl; thus, the promoters of the gene producing th[r] ... See full document
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Interactions of the transcription factors MIBP1 and RFX1 with the EP element of the hepatitis B virus enhancer.
... HBV enhancer I region (nt 966 to 1308) has been subdivided into three domains: the modulatory (nt 966 to 1119), core enhancer (nt 1119 to 1168), and basal promoter-X open reading frame regions (nt 1168 to ... See full document
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The Enhancer I Core Region Contributes to the Replication Level of Hepatitis B Virus In Vivo and In Vitro
... in enhancer I alter the binding of HNF3 or HNF4 to their putative binding sites, gel shift experiments were performed using oligonucleo- tides representing either the wt or the mutated HNF3 and -4 ...HuH-7 ... See full document
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Woodchuck Hepatitis Virus Enhancer I and Enhancer II Are Both Involved in N-myc2 Activation in Woodchuck Liver Tumors
... by hepatitis B virus ...tis virus (WHV) and ground squirrel hepatitis virus, similarly increase the risk of liver cancer development in their hosts (17, 24) and thus ... See full document
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Identification of factor-binding sites in the duck hepatitis B virus enhancer and in vivo effects of enhancer mutations.
... Though mutations at the HNF1 site and the two HNF3 sites seemed to make the virus enhancer slightly defective in the LMH liver cell line, as expected from the assays with the hGH reporte[r] ... See full document
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Identification of valid reference genes for microRNA expression studies in a hepatitis B virus replicating liver cell line
... We make use of the human liver cell model HepG2 tet-on for our in vitro studies due to lack of primary tissue from asymptomatic children with CHB. We introduced a doxy- cycline-inducible vector containing ... See full document
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Influence of Hepatitis B and Hepatitis C Virus Infections and Human Immunodeficiency Virus Therapy on Liver Status of Patients with Human Immunodeficiency Virus
... Plus HIV version 2 Kit (Steenvoorde, France) which is a microplate double-sandwich enzyme- linked immunosorbent assay. In the first step, the sample (75 µl) is incubated with biotinylated anti- p24 polyclonal antibodies ... See full document
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Production of hepatitis delta virus and suppression of helper hepatitis B virus in a human hepatoma cell line.
... By transient transfection of the human hepatoma cell line HuH-7 with a plasmid, pA3HBV3.8, containing the 3.8-kb HBV DNA sequence, which is able to produce the pregenomic HBV RNA, we hav[r] ... See full document
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Hepatitis C and not Hepatitis B virus is a risk factor for anti tuberculosis drug induced liver injury
... serial liver function test once in 2 weeks, in- cluding aspartate aminotransferase (AST), alanine ami- notransferase (ALT), and total bilirubin, symptoms of hepatitis including anorexia, nausea, vomiting, ... See full document
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Outcome of Patients with Hepatitis B Virus and Human Immunodeficiency Virus Infections Referred for Liver Transplantation
... for liver transplantation had a high prevalence of lamivudine-resistant HBV infection and that use of drugs to suppress HBV replication in these patients ...of liver-related ... See full document
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Detection of Hepatitis Virus B And C in Archival Autopsy Specimens of Liver Cirrhosis
... In conclusion, this should be the first proof for the earliest occurrence of HCV infection in 1909 by analyzing archival autopsied liver specimens. We also demonstrated by nested RT-PCR using type-specific primers ... See full document
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Molecular characterization of hepatitis B virus in liver disease patients and asymptomatic carriers of the virus in Sudan
... of hepatitis B virus DNA and alanine aminotransferase levels were ...of hepatitis B e antigen-positivity and higher viral loads compared to patients infected with genotype ...for ... See full document
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Mapping of B-cell epitopes of the human hepatitis B virus X protein.
... The carboxy-terminal half of the HBx antigen was the most frequent target for anti-HBx antibodies in sera of patients with viral hepatitis and contained an immunodominant antigenic regio[r] ... See full document
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The role of mutations in core protein of hepatitis B virus in liver fibrosis
... The structure of core protein is largely α-helical rods with C-terminal basic tail that interact closely with viral RNA pregenome or the viral DNA genome [11]. The C-terminal of the core protein is highly conserved with ... See full document
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Association of vitamin D deficiency with hepatitis B virus related liver diseases
... vitamin D levels (<4.39 ng/ml). Vitamin D levels were mostly inadequate (<30 ng/ml) in both HBV patients (84.3 %) and controls (81.7 %); the difference, however, was not significant. When vitamin D levels were ... See full document
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