[PDF] Top 20 The Dimensionality of Genomic Information and Its Effect on Genomic Prediction
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The Dimensionality of Genomic Information and Its Effect on Genomic Prediction
... GBLUP-based methods require an inverse of the genomic relationship matrix (GRM). A direct inverse has a cubic cost and can be computed efficiently for perhaps up to 150,000 individuals. Due to the popularity of ... See full document
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Combining pedigree and genomic information to improve prediction quality: an example in sorghum
... crops. Genomic prediction models can make use of pedigree information to account for the residual polygenic effects not captured by ...and genomic information on prediction ... See full document
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Imputation of parent-offspring trios and their effect on accuracy of genomic prediction using Bayesian method
... linkage information from close relatives) and population-based methods, which use population linkage disequilibrium information (Sargolzaei, ...using genomic information from its family ... See full document
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Domestic and Interbull information in the single step genomic evaluation of Holstein milk production
... genetic information simultaneously is used for genomic ...ression genomic prediction procedure (RRBLUP), and Bayesian procedures, and the genomic best linear unbiased prediction ... See full document
7
Genomic BLUP Decoded: A Look into the Black Box of Genomic Prediction
... decreasing information from additive-genetic relationships may result in a smaller increase of accuracy observed with real data or even a decay if LD information cannot compensate for that ...with ... See full document
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Deregressing estimated breeding values and weighting information for genomic regression analyses
... which information should be weighted, if at all, has been apparent for some time in literature related to discover- ing and fine-mapping quantitative trait loci ...using information for QTL discovery has ... See full document
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The Effect of Linkage Disequilibrium and Family Relationships on the Reliability of Genomic Prediction
... of genomic prediction was predicted for five scenarios with simulated genotypes for selection candidates and using a reference population composed of real individuals with genotypic ...of genomic ... See full document
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Genomic Prediction for Quantitative Traits Is Improved by Mapping Variants to Gene Ontology Categories in Drosophila melanogaster
... high-resolution genomic polymorphism data is important for personalized medicine in humans, plant and animal breeding, and adaptive ...to genomic features such as genes and their gene ontology categories ... See full document
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Best practices for bioinformatic characterization of neoantigens for clinical utility
... binding prediction algorithms (variability among binding predic- tions); the integration of both DNA and RNA data (expres- sion of neoantigen candidate genes or transcripts and expression of variant alleles); the ... See full document
21
Accurate Genomic Prediction of Human Height
... genotype information was collected for 488,377 individuals for 805,426 SNPs and then subsequently ...negligible effect on our predictor construction: specifically, using the procedure of setting aside a ... See full document
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Locally Epistatic Genomic Relationship Matrices for Genomic Association and Prediction
... the prediction accuracies of models with Gaussian are often higher than those of the models with linear kernel (De Los Campos 2008; González-Camacho et ...genetic effect, additive plus nonadditive) and the ... See full document
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Immunoinformatics and epitope prediction in the age of genomic medicine
... to its corresponding output for a given training data-set of known input and output values (learning from ...(e.g., prediction of peptide binding ... See full document
12
Coverage of genomic medicine: information gap between lay public and scientists
... First, using a thesaurus search of the Igaku Chuo Zasshi database (Japan Medical Abstracts by NPO Japan Medical Abstracts Society), we extracted Japanese terms related to the word “genome” in order to define the ... See full document
8
Visualizing genomic information across chromosomes with PhenoGram
... Copy-number variants (CNVs) are a growing area of genetic variant exploration for neurodevelopmental disorders. Recently, a comparison was made of two microarray tech- nologies used in the detection of CNVs. Figure 7 ... See full document
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Evaluation of Genomic Prediction for Pasmo Resistance in Flax
... years using the RR-BLUP model built with the SNP-500QTL marker set and the PS-mean phenotypic data using 195. all 370 accessions as training data set.[r] ... See full document
16
Genomic regions and genes associated with carcass quality in Nelore cattle
... Several genomic regions associated with small effects demonstrate the complexity of the phenotypes related to carcass quality; they do not depend only on the effects of a few genes to determine their ... See full document
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Software for detecting gene-gene interactions using Multifactor Dimensionality Reduction: Introducing the R package MDR
... In k-‐fold cross-‐validation, the data is randomly split into k equal intervals, with where k-‐1 intervals are used for training and one interval is used for testing [Motsinger and Ritchie 2006]. The best MDR model ... See full document
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Comparative genomic analyses of a virulent pseudorabies virus and a series of its in vitro passaged strains
... China. Genomic analysis of PRV variants isolated from these outbreaks has shown that they are evolution- arily divergent from European-American strains [7], and lack of complete protection by the Bartha-K61 ... See full document
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Effect of marker density and trait heritability on the accuracy of genomic prediction over three generations
... in genomic selection, the high cost of genotyping a large population prevents the broader implementation of genomic selection in many livestock species including the native cattle ...reduce genomic ... See full document
6
Complete genome sequence of Roseophage vB_DshP-R1, which infects Dinoroseobacter shibae DFL12
... genomes Genomic organization (Figure 3) and intergenic homologies (Additional file 2: Table S2) among ...of its genome length) that were identified as similar to the corresponding proteins of the typical ... See full document
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