[PDF] Top 20 Enhanced Mutability Associated with a Temperature-Sensitive Mutant of Vesicular Stomatitis Virus
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Enhanced Mutability Associated with a Temperature-Sensitive Mutant of Vesicular Stomatitis Virus
... Track 1, Uninfected BHK-21 with cells RNA; track 2, clone 80/21/9 of fast-migrating pre-G polypeptides translated fr-om infected BHK-21 cell RNA; track 3, VSV Indiana wild- type polypept[r] ... See full document
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Growth and Maturation of a Vesicular Stomatitis Virus Temperature-Sensitive Mutant and Its Central Nervous System Isolate
... However, there did not appear to be any alteration of the maturation and assembly of the viral proteins at 370C, since the measurements for the distribution of viral structural proteins [r] ... See full document
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Neuroblastoma Cell Fusion by a Temperature-Sensitive Mutant of Vesicular Stomatitis Virus
... Two lines of evidence suggest that the expression of G at the cell surface promotes this polykaryocyte formation: i inhibition of glycosylation, which may be involved in the migration of[r] ... See full document
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Assignment of the temperature-sensitive lesion in the replication mutant A1 of vesicular stomatitis virus to the N gene.
... 44 Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest The replication defect in the temperature-sensitive mutant Al of the New Jersey serotype Hazelhurst subtype of vesicu[r] ... See full document
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Insertion of Enhanced Green Fluorescent Protein in a Hinge Region of Vesicular Stomatitis Virus L Polymerase Protein Creates a Temperature-Sensitive Virus That Displays No Virion-Associated Polymerase Activity In Vitro
... We initiated the above work to shed light on the domain structure of the VSV L polymerase protein. Absent structural information, it remains unclear whether the six blocks of con- served sequences shared by all MNV L ... See full document
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Effect of Temperature-Sensitive Mutation on Activity of the RNA Transcriptase of Vesicular Stomatitis Virus New Jersey
... The heat stability of the mutant ts Bl was similar to that of wild-type virus, and in vitro RNA synthesis was fully restored when the temperature was lowered to 310C after 30 min of prei[r] ... See full document
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Analysis of the defects of temperature-sensitive mutants of vesicular stomatitis virus: intracellular degradation of specific viral proteins.
... Certain viral proteins encoded by the mutant strains, usually the putative mutant protein for the assigned complementation group, were shown to be degraded more rapidly at the nonpermiss[r] ... See full document
9
Defective Particles in BHK Cells Infected with Temperature-Sensitive Mutants of Vesicular Stomatitis Virus
... All varieties of defective particle interfered with the multiplication of mutant and wild-type virus at the permissive temperature at early times of infection but failed to complement vi[r] ... See full document
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Location of the Transcription Defect in Group I Temperature-Sensitive Mutants of Vesicular Stomatitis Virus
... In order to locate the temperature-sensitive transcription defect in the mutants, wt and ts mutant virions were fractionated by Triton X-100-high salt solubilizer into a sedimentable rib[r] ... See full document
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Further characterization of the vesicular stomatitis virus temperature-sensitive O45 mutant: intracellular conversion of the glycoprotein to a soluble form.
... 210 Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest Reexamination of the viral products of ts045, a glycoprotein mutant of vesicular stomatitis virus, showed that at 39[r] ... See full document
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Persistent infection of a temperature-sensitive G31 vesicular stomatitis virus mutant in neural and nonneural cells: biological and virological characteristics.
... DALCANTO,3 AND MARY KATHLEEN RUNDELL4 Departments of Medicine,' Pathology,3 and Microimmunology,4 Northwestern University Medical School, and Veterans Administration Lakeside Medical Cen[r] ... See full document
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Temperature-Sensitive Mutants of Vesicular Stomatitis Virus: In Vitro Studies of Virion-Associated Polymerase
... CORMACK The Manitoba Cancer Treatment and Research Foundation, Winnipeg 3, Canada The temperature dependence of the virion-associated polymerase activity of six temperature-sensitive ts [r] ... See full document
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Phenotypic revertants of temperature-sensitive M protein mutants of vesicular stomatitis virus: sequence analysis and functional characterization.
... 256 Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest Twenty-five spontaneous temperature-stable revertants of four different temperature-sensitive ts M protein mutants c[r] ... See full document
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Effects of temperature and antibody on the cyclid growth of vesicular stomatitis virus.
... The addition of neutralizing antibodies to such continuous infections by wildtype virus was to see whether cyclic production 161 Downloaded from http://jvi.asm.org/ on November 10, 2019 [r] ... See full document
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Rifampin-susceptible mutant of vesicular stomatitis virus: protein and RNA synthesis.
... When rifampin was present only Rif+ was analyzed under these conditions and during the first 4 h p.i., an accumulation of in the presence of rifampin, the intracellular viral proteins wa[r] ... See full document
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Regulation of viral transcription by the matrix protein of vesicular stomatitis virus probed by monoclonal antibodies and temperature-sensitive mutants.
... Enzymatically active RNP VS virions were prepared in two different forms To isolate RNP cores with M protein attached Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest Th[r] ... See full document
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Envelope Proteins of Vesicular Stomatitis Virus: Effect of Temperature-Sensitive Mutations in Complementation Groups III and V
... Three hours 1220 Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest All five major viral proteins were synthesized in chicken embryo cells infected with vesicular stomatit[r] ... See full document
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Aberrant polyadenylation by a vesicular stomatitis virus mutant is due to an altered L protein.
... However, experiments in which purified M protein fractions were added to transcribing nucleocapsids suggested that this was It is extremely difficult if not impossible to completely excl[r] ... See full document
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Vesicular stomatitis virus mutant with altered polyadenylic acid polymerase activity in vitro.
... To obtain an estimate of the length of the polyA in polyA+ RNA from either wt or tsG16I in vitro transcription reactions, I digested polyA+ RNA made at 31°C and labeled with both [3H]AMP[r] ... See full document
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Aberrant glycoprotein mRNA synthesized by the internal deletion mutant of vesicular stomatitis virus.
... Oligonucleotide sequence analyses indicate that vesicular stomatitis virus large defective interfering virus particle RNA is made by internal deletion: evidence for similar transcription[r] ... See full document
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