[PDF] Top 20 Expression of herpes simplex virus type 2 latency-associated transcript in neurons and nonneurons.
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Expression of herpes simplex virus type 2 latency-associated transcript in neurons and nonneurons.
... Latent infection of mouse dorsal root ganglion was investigated with the BamHI p fragment of HSV-2, which resulted in evidence of ganglion hybridization, and other fragments representing[r] ... See full document
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Mutations in the 5' end of the herpes simplex virus type 2 latency-associated transcript (LAT) promoter affect LAT expression in vivo but not the rate of spontaneous reactivation of genital herpes.
... of neurons in ganglia during acute infection, implying a defect in the switch from active to latent ...of neurons from which virus could subsequently re- ...LAT 2 mutants, and to a lesser ... See full document
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Analysis of Protein Expression from within the Region Encoding the 2.0-Kilobase Latency-Associated Transcript of Herpes Simplex Virus Type 1
... LAT-GFP virus during either productive or latent ...recombinant virus, vLAT-GFP, was produced by cotransfection of the plasmid p⌬CMV(H)GFP and parental F strain DNA, followed by several rounds of plaque ... See full document
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Tissue-Specific Splicing of the Herpes Simplex Virus Type 1 Latency-Associated Transcript (LAT) Intron in LAT Transgenic Mice
... of herpes simplex virus type 1 (HSV-1) latency-associated transcript (LAT) expres- sion and processing in the absence of other cis and trans viral functions, a transgenic ... See full document
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Neuronal Subtype Determines Herpes Simplex Virus 1 Latency-Associated-Transcript Promoter Activity during Latency
... ABSTRACT Herpes simplex virus (HSV) latency in neurons remains poorly under- stood, and the heterogeneity of the sensory nervous system complicates mechanis- tic ...mouse neurons ... See full document
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Herpes Simplex Virus Type 1 Latently Infected Neurons Differentially Express Latency-Associated and ICP0 Transcripts
... gene expression during HSV-1 latency (20, ...(TG) neurons (9, ...during latency, as recently reported by Chen et ...gene expression from quiescent genomes in cells in culture and viral ... See full document
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Herpes simplex virus type 1 latency-associated transcript (LAT) promoter deletion mutants can express a 2-kilobase transcript mapping to the LAT region.
... The data for KOS/29 LAT-related RNA expression suggest the presence of a second promoter in the LAT gene which can function in tissue culture infection, at low levels in acute infection [r] ... See full document
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The Herpes Simplex Virus Type 1 Latency-Associated Transcript (LAT) Enhancer/rcr Is Hyperacetylated during Latency Independently of LAT Transcription
... erty associated with a number of cellular transcriptional en- hancers (18), and it is important to note that enhancer activi- ties have previously been associated with the region of LAT containing the 5 ⬘ ... See full document
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A Novel Herpes Simplex Virus Type 1 Transcript (AL-RNA) Antisense to the 5′ End of the Latency-Associated Transcript Produces a Protein in Infected Rabbits
... dLAT2903 virus per eye, and serum was collected from individual rabbits 57 days ...which latency had been well ...1, 2, and 3) recognized a band corre- sponding in mobility to the AL band recognized ... See full document
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A 348-base-pair region in the latency-associated transcript facilitates herpes simplex virus type 1 reactivation.
... tion transcript termination signal inserted at various sites along the primary transcript, we present evidence that the epineph- rine-induced reactivation phenotype resides primarily within the 5 9 region ... See full document
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A Herpes Simplex Virus Type 1 Latency-Associated Transcript Mutant with Increased Virulence and Reduced Spontaneous Reactivation
... the virus, ...the virus, ...(Table 2, experiment 3, column 3) also indicated that ...wild- type viruses) and that spontaneous reactivation of ...Table 2, experiment 3, columns 4 and ... See full document
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Transcription of the Herpes Simplex Virus Latency-Associated Transcript Promotes the Formation of Facultative Heterochromatin on Lytic Promoters
... is associated with H3K9me3 and H3K27me3 was perhaps surprising given that transcription initiates from the LAT ...infection neurons do not express detect- able levels of the LATs (10, 34, 39, ...long-term ... See full document
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A herpes simplex virus type 1 latency-associated transcript mutant reactivates with normal kinetics from latent infection.
... Expression of herpes simplex virus type 1 latency-associated transcripts in the trigeminal ganglia of mice during acute infection and reactivation of latent infection.. Expression of her[r] ... See full document
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PrPc Expression Influences the Establishment of Herpes Simplex Virus Type 1 Latency
... infected neurons by means of in situ ...detect latency-associated transcripts (LATs) ⬎30 days postinfection ...pSLAT 2 (kindly provided by ...positive neurons per ... See full document
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Interactions between Herpesvirus Entry Mediator (TNFRSF14) and Latency-Associated Transcript during Herpes Simplex Virus 1 Latency
... HSV-1 latency and the HSV-1 reactivation ...increasing expression of HVEM in latently infected ...influences latency, reactivation, and survival of gangli- on-resident T ...HSV-1 latency and ... See full document
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Herpes Simplex Virus 2 MicroRNA miR-H6 Is a Novel Latency-Associated Transcript-Associated MicroRNA, but Reduction of Its Expression Does Not Influence the Establishment of Viral Latency or the Recurrence Phenotype
... The herpes simplex virus 2 (HSV-2) viral microRNA (miRNA) designated miR-H6 is located upstream of the latency-associated transcript (LAT) promoter region on the ... See full document
9
The herpes simplex virus type 1 2.0-kilobase latency-associated transcript is a stable intron which branches at a guanosine.
... Herpes simplex virus type 1 (HSV-1) is neurotropic virus capable of forming latent infections for the lifetime of an ...During latency, transcription is restricted to a single ... See full document
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Analysis of the promoter and cis-acting elements regulating expression of herpes simplex virus type 2 latency-associated transcripts.
... Novel cis element in 2LATP. Because Ft3 seemed so impor- tant to the overall activity of 2LATP, we sought to characterize it more fully. The sequence of Ft3 is GC rich. A computer search of the database sites from the ... See full document
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Herpes Simplex Virus Latency-Associated Transcript Sequence Downstream of the Promoter Influences Type-Specific Reactivation and Viral Neurotropism
... Herpes simplex virus (HSV) establishes latency in sensory nerve ganglia during acute infection and may later periodically reactivate to cause recurrent ...HSV type 1 (HSV-1) reactivates ... See full document
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The 2.2-Kilobase Latency-Associated Transcript of Herpes Simplex Virus Type 2 Does Not Modulate Viral Replication, Reactivation, or Establishment of Latency in Transgenic Mice
... Establishment of mouse lines transgenic for the HSV-2 ma- jor LAT. The LATpa transgene spans the upstream LAT pro- moter regulatory region, the major LAT coding sequence, about 1 kb downstream of the 3⬘ end of the ... See full document
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