[PDF] Top 20 Co expression and regulation of p53 and muc1 in human carcinomas
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Co expression and regulation of p53 and muc1 in human carcinomas
... different human malignancies. MUC1 is positioned at the cell membrane as a complex of N-terminal (composed of 20 AA tandem repeats) and C-terminal ...July-2015). MUC1 C-terminal domain ... See full document
6
Original Article Relationship of Fas, FasL, p53 and bcl-2 expression in human non-small cell lung carcinomas
... The bcl-2 oncogene is a suppressor of apopto- sis and overexpression of bcl-2 onco- gene has been reported to be an important mechanism of apoptotic resistance in Fas- expressing malignant cells [27]. The only published ... See full document
9
p53 Expression in Triple Negative Breast Carcinomas: Evidence of Age Related and Racial Differences
... breast carcinomas (TNBC), are defined by the absence of estrogen receptor (ER), progesterone receptor (PR) and human epidermal growth factor receptor 2 (HER2) ...gene expression profiles, but ... See full document
6
Original Article Silencing of DYRK1B improves the sensitivity of human cervical carcinoma cells to cis-platinum
... The expression level of DYRK1B in human cervical cancer cell lines was detected by real-time ...highest expression of DYRK1B, and were infected with a lentivirus containing small hairpin RNA (shRNA), ... See full document
10
Regulation of expression of the multidrug resistance protein MRP1 by p53 in human prostate cancer cells
... for detection of MRP1. The blots were incubated in blocking solution consisting of 5% milk and 3% BSA in PBS-T for 2 hours at 25°C and were then immunoblotted with monoclonal anti-human p53 protein clone ... See full document
8
Correlation between koilocytes and human papilloma virus in nasopharyngeal Carcinomas
... normal human keratinocytes to immortalize forms in vitro (Hwang et ...The expression of oncoproteins E6 and E7 interferes with crucial cellular mechanisms such as cell cycle, regulation and apoptosis ... See full document
7
Expression of KI67, P53 and MUC1 in Renal Cell Carcinoma in Correlation with Nuclear Grade
... fraction of a specified cell population and is widely as a proliferation marker in many of the human tumours. The fraction of Ki-67-positive tumor cells is often associated with the clinical course of various ... See full document
174
Epigenetic regulation of mucin genes in human cancers
... of MUC1 were not exam- ined for more than a decade after initial methylation analysis of the MUC1 coding region (Zrihan-Licht et ...that MUC1 gene expression is regulated by DNA methylation ... See full document
12
Key words
... I expression and the staging and grad- ing of ovarian tumors [2, ...I expression was associated with poorly differentiated ovarian carcinomas in the cur- rent ...I expression was associated ... See full document
8
High prevalence of mutations of the p53 gene in poorly differentiated human thyroid carcinomas
... homozygous p53 mutations were ...which p53 mutations were not detected in exons 5-8 had markedly decreased p53 mRNA levels, suggesting the presence of a structural abnormality of either p53 ... See full document
7
Combination of curcumin and bicalutamide enhanced the growth inhibition of androgen-independent prostate cancer cells through SAPK/JNK and MEK/ERK1/2-mediated targeting NF-κB/p65 and MUC1-C
... up- regulation of insulin-like growth factor-binding protein 3 (IGFBP3) ...that MUC1-C subunit suppressed AR expression through a posttranscriptional mechanism and resisted to bicalutamide treatment ... See full document
11
The Study of the Expression of P53 and Ki-67 in Gastric Carcinomas and their Correlation with Clinico-Pathological Variables.
... the carcinomas were classified into 4 groups: T1 (invasion of mucosa and submucosa), T2 (invasion of muscularis propria and subserosa), T3 (invasion of serosa) and T4 (invasion of adjacent organs), and according ... See full document
151
<p>Thyronamine regulation of TAAR1 expression in breast cancer cells and investigation of its influence on viability and migration</p>
... In this study, the influence of T 3 and thyronamines (T 1 AM) on TAAR1 expression has been analyzed in MCF-7 and T47D breast cancer cell lines. In a previous study, we found that TAAR1 overexpression (IRS ≥ 6) was ... See full document
11
Segmentation gene expression patterns in Bactrocera dorsalis and related insects: regulation and shape of blastoderm and larval cuticle
... al., 1996). These reports extended our understanding how the interplay of gap genes control the different even-skipped stripes, and defined an initial set of transcriptional activators and repres- sors for each of the ... See full document
13
A negative regulation loop of long noncoding RNA HOTAIR and p53 in non-small-cell lung cancer
... Cells were lysed by radioimmunoprecipitation buffer and proteins were then extracted and quantified by Bradford reagent. An amount of 50 mg of total proteins were loaded on Nupage 4%–12% polyacrylamide gels (Thermo ... See full document
8
MUC1 immunotherapy against a metastatic mammary adenocarcinoma model: Importance of IFN-gamma
... of MUC1 were expressed (> 85%), there were low levels of all other cell surface molecules needed for T cell activation inclu- ding MHC class I (< 6%), MHC class II, CD80, ICAM-2, CD28, LFA-2 and ... See full document
11
mdm2 mRNA Level is a Prognostic Factor in Soft Tissue Sarcoma
... protein expression was detected by West- ern blots analysis and normalized to actin ex- ...four P53 expression groups divided into zero, mod- est, marked or strong expression was ...lost ... See full document
10
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... A technique of manual tissue array confirming sufficient representation of different areas in the cores was used for IHC [9]. The primary antibodies used were MUC1 (Clone Ma 695, Novocastra) and MUC5AC (Clone ... See full document
5
Acetylation of the Cell-Fate Factor Dachshund Determines p53 Binding and Signaling Modules in Breast Cancer
... between p53 and DACH1, immunoprecipitation (IP) –Western blotting (WB) was conducted using an antibody, either to p53 with sequential WB to DACH1, or immunoprecipitation with a DACH1 specific antibody and ... See full document
13
<p>Bioinformatics Analysis and RNA-Sequencing of SCAMP3 Expression and Correlated Gene Regulation in Hepatocellular Carcinoma</p>
... and expression of various genes involved in ...PPAP2B expression to induce metastasis, SNRK expression to suppress differentia- tion and ARID4A expression to modulate several transcrip- ... See full document
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