[PDF] Top 20 Formulation and Evaluation of Floating Tablets using Nimesulide as a Model Drug

... Both loose bulk density (LBD) and tapped bulk density (TBD) were determined. A quantity of 2gm of powder from each formula, previously lightly shaken to break any agglomerates formed, was introduced into a 10-ml ... See full document

... of drug release, reduces drug waste, and improves the drug solubility that are less soluble in a high pH environment (Garg R, et al, ...Gastroretentive drug delivery is an approach to prolong ... See full document

... of floating tablets of Metronidazole. The effervescent-based floating drug delivery was a promising approach to achieve in-vitro ...in drug release. The polymer composition affects the ... See full document

... the tablets throughout the batches ensures good tablet strength and shape and is also important with respect to packaging and ...the tablets should be restricted within 5% or less of an established standard ... See full document

... retentive floating matrix formulation of Silymarin by using various polymers were ...by using different ...the formulation was developed by using different concentrations of ... See full document

... gabapentin formulation (gabapentin TID) must usually be taken three times a day for optimal ...retentive formulation of gabapentin was recently approved by the US Food and Drug Administration (FDA) ... See full document

... anitidine hydrochloride is a histamine H2-receptor antagonist that inhibits stomach production. Its chemical name is N'-[2-[[5-(Dimethylaminomethyl)-2- furyl]methylsulfanyl]ethyl]-N-methyl-2-nitro- ethene-1,1-diamine ... See full document

... fluoroquinolone drug class considered to be a second-generation ...effervescent floating tablets were developed in six different formulations (F1 to F6) by employing different grades of polymers and ... See full document

... the tablets floated, and remained buoyant without ...total floating time (TFT). Formulation F10 containing HPMC K15M, HPMC K100M and Carbopol Ca934P showed good BLT of 110 sec and TFT of more than 24 ... See full document

... -1 using KBr disk method. This KBr disks were prepared by taking drug and KBr in a ratio of 1:100 ...pressed using KBr pellet press at a pressure of 20,000 psi for 1 ... See full document

... of floating tablets of ...Amoxicillin floating tablets were prepared by using polymers such as HPMC, Guar gum, carbopol, and ethyl ...form using Guar gum and Ethyl cellulose was ... See full document

... Further formulation development was carried out increasing the concentration of polymer 25% concentration of HPMC K15 was ...98% drug release was observed in 18 ...the formulation development was ... See full document

... the formulation shown in table ...of drug within polymers. Drug release studies were made to determine whether the release of the drug is slow enough for at least 12 ...that formulation ... See full document

... gastroretentive drug delivery system of ranitidine ...on drug release profile and floating properties were ...the drug release ...retentive formulation. A theoretical dissolution ... See full document

... The drug release rate from Floating mucoadhesive tablets was studied using the USP type II dissolution test ...apparatus. Tablets were supposed to release the drug from one side ... See full document

... The drug release rate from floating microspheres was carried out using the USP dissolution paddle assembly (Model DT-06, Erweka, ...of floating microspheres equivalent to 100 mg ... See full document

... core tablets were subjected for the drug content. Twenty tablets were finely powdered, quantity of the powder equivalent to one tablet weight of Esomeprazole were accurately weighed, transferred to a ... See full document

... However, one meta-analysis looking at the outcome of pregnancies involving Quinolone use in the first trimester found no increased risk of malformations. They are also contraindicated in children due to the risks of ... See full document

... Twenty tablets were taken and amount of drug present in each tablet was ...The tablets were crushed in a mortar and the powder equivalent to 100mg of drug was transferred to 100ml standard ... See full document

... (DMB-SR) tablets using floating technique to prolong the gastric residence time and compared their pharmacokinetic behavior with conventional sustained release ...DMB-SR floating ... See full document