[PDF] Top 20 Formulation and evaluation of gastroretentive floating tablets of rebamipide

... optimized formulation RF22 containing Gellan Gum and a gas-generating ...of Rebamipide and marketed product when compared, the optimized formulation RF22 showed drug release of ...optimized ... See full document

... was formulation and evaluation of gastroretentive floating tablets of TRZ for prolongation of gastric residence time with a view to deliver the drug at the sustained and controlled ... See full document

... The floating tablets of Cefadroxil were prepared to increase the gastric retention and to improve the bioavailability of the ...The floating tablets were formulated using Xanthan gum, Guar gum ... See full document

... Tablets were made by direct compression. Venlafaxine HCl was mixed with the required quantities of polymers HPMC K4M, HPMC K15M, HPMC K100, sodium bicarbonate and citric acid by geometric mixing. The powder blends ... See full document

... to zero order, first order kinetic equation, higuchi’s and korsmeyer’s models in order to determine the mechanism of drug release. When the regression coefficient values of were compared, it was observed that ‘r’ values ... See full document

... Integrity of the drug in the formulation was checked by taking an IR spectrum of the selected formulation along with the drug and other excipients. The spectra obtained were compared using Shimadzu FTIR ... See full document

... Weight variation test: To study the weight variation, twenty tablets were taken and their weight was determined individually and collectively on a digital weighing balance. The average weight of one tablet was ... See full document

... simulated gastric fluid. Physical mixtures were evaluated for bulk density, tapped density, Carr’s index and Hausner ratio. Characterization of drug and polymer mixture were done by performing FTIR and it was concluded ... See full document

... the floating of tablet as it when react with the gastric fluid it produces carbon dioxide gas which is entrapped by the hydrophilic matrices leading to the increase in volume of dosages form and finally results in ... See full document

... the gastroretentive forms that precisely control the release rate of target drug to a specific site which facilitate an enormous impact on health ...retentive floating tablets of Prochlorperazine ... See full document

... the floating behavior i.e. floating lag time and floating ...total floating time for the formulations was more than 12 hours irrespective to the amount of sodium bicarbonate whereas ... See full document

... Different tablets formulations (F1-F9) were prepared by direct compression ...betahistine floating tablets was shown in Table 1. Table 1 Formulation composition of betahistine hydrochloride ... See full document

... Gastroretentive floating tablets of lafutidine were prepared by wet granulation technique using different concentrations of Gum Kondagagu, Gum olibanum and Locust bean ... See full document

... optimized formulation F8 was found to ...optimized formulation F8 followed Higuchi’s kinetics, since the regression coefficient is ...optimized formulation F8 is ... See full document

... formulating gastroretentive floating tablet using solid dispersion (SD) of the ...the formulation of solid dispersion. Formulation batch SD8 was found to be optimized according to the face ... See full document

... optimized floating tablets F7 were preferred for stability study on the source of in vitro buoyancy and in-vitro drug dissolution ...The tablets were investigated at 40°C/75% RH for 2 ...the ... See full document

... HBS tablets were evaluated for hardness, friability, uniformity of weight, swelling index, floating lag time, in-vitro floating time, in-vitro ...all tablets was less than 1% ...of ... See full document

... a gastroretentive dosage ...a formulation prepared using combinations of natural and synthetic polymers usually generates better results as it follows various mechanisms of ... See full document

... dosage forms, tablet or capsules, will result in dissolution of the drug in the gastric fluid. They dissolve in the gastric fluid would be available for absorption in the small intestine after emptying of the stomach ... See full document

... FTIR spectroscopy was carried out to study the com- patibility of pure drug Lafutidine with the polymer HPMC K4M, Sodium alginate and Ethyl cellulose used in the formulation of floating microspheres. All ... See full document