[PDF] Top 20 Is Function of the Drosophila Homeotic Gene Ultrabithorax Canalized?
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Is Function of the Drosophila Homeotic Gene Ultrabithorax Canalized?
... This observation does not, however, necessarily imply that the traits are under control of different genes, as fine structure analy- sis indicates that the same alleles can [r] ... See full document
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Identification of target genes regulated by homeotic proteins in Drosophila melanogaster through genetic selection of Ultrabithorax protein-binding sites in yeast.
... It has been proposed that yeast cells might be used to identify target genes of specific transcriptional regulators by selecting DNA fragments that contain binding sites[r] ... See full document
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trithorax and the regulation of homeotic gene expression in Drosophila: a historical perspective
... trx function is not restricted to the regulation of just the ANT- C and BX-C: even in the wing trx clones exhibited a mutant ...selector gene, that is a gene that controls the identity of a specific ... See full document
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Genetic analysis of transvection effects involving cis-regulatory elements of the Drosophila Ultrabithorax gene.
... Our results show that the Ubx’ allele retains wild-type functions whose effectiveness can be reduced (1) by additional cis mutations in the bxd region or in introns of the U[r] ... See full document
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Direct regulation of knot gene expression by Ultrabithorax and the evolution of cis regulatory elements in Drosophila
... To better understand how UBX regulates morphology, we would ideally like to know all target genes on which it acts and the DNA regulatory sequences through which it exerts this control. Characterization of these ... See full document
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Integration of RNA processing and expression level control modulates the function of the Drosophila Hox gene Ultrabithorax during adult development
... Although most metazoan genes undergo alternative splicing, the functional relevance of the majority of alternative splicing products is still unknown. Here we explore this problem in the Drosophila Hox gene ... See full document
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Ras1-Mediated Modulation of Drosophila Homeotic Function in Cell and Segment Identity
... Since Gapl is generally viewed as a specific antagonist of Rasl' function, this supported our interpretation that Rasl is the relevant locus in the 85D11-14 interval that modif[r] ... See full document
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Drosophila ptip is essential for anterior/posterior patterning in development and interacts with the PcG and trxG pathways
... of gene expression by the PcG/trxG ...to Drosophila Trithorax (Cho et ...the function of ptip in Drosophila, we utilized the Kc cell line to assay for gene expression in the presence or ... See full document
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The Ultrabithorax Hox gene of Drosophila controls haltere size by regulating the Dpp pathway
... The function and distribution of Dpp, like that of Wingless (Wg) or Hh, depends on the presence of a kind of cell-surface molecule named heparin sulphate proteoglycans (reviewed by Lin, ...in Drosophila are ... See full document
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The Drosophila Hox gene Ultrabithorax controls appendage shape by regulating extracellular matrix dynamics
... its function, the mechanisms underlying organ shape are largely ...In Drosophila, the wings and halteres, homologous appendages of the second and third thoracic segments, respectively, bear different forms: ... See full document
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Potential Variance Affecting Homeotic Ultrabithorax and Antennapedia Phenotypes in Drosophila melanogaster
... of homeotic mutations into wild-type genetic backgrounds results in a wide variety of phenotypes and implies that major effect modifiers of extreme phenotypes are not uncommon in natural populations of ...in ... See full document
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A comprehensive catalog of post-translational modifications of Drosophila melanogaster HOX protein, Sex combs reduced
... Genetic analysis that either mimics constitutive dephosphorylation by changing a phosphorylatable amino acid residue like S/T/Y to a non-phosphorylatable residue, alanine (A) or mimics constitutive phosphorylation by ... See full document
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Segment specific prevention of pioneer neuron apoptosis by cell autonomous, postmitotic Hox gene activity
... the Drosophila dMP2 and MP1 pioneer neurons undergo segment-specific apoptosis at a late developmental ...initial function of these neurons depends on Hox function, their late, segment- specific ... See full document
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Transvection and Silencing of the Scr Homeotic Gene of Drosophila melanogaster
... Figure 2.—Molecular ge- netic map of the distal re- gion of the ANTC. The top shows the location of the transcription units in 210 kb of genomic DNA from poly- tene chromosome bands 84B1–2. Both the P1 and P2 ... See full document
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The lawc Gene Is a New Member of the trithorax-Group That Affects the Function of the gypsy Insulator of Drosophila
... lawc gene result in a pleiotropic phenotype that includes homeotic transformation of the arista into ...affect homeotic gene transcription, causing ectopic expression of Antennapedia in the ... See full document
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Polycomb dependent Ultrabithorax Hox gene silencing induced by high Ultrabithorax levels in Drosophila
... results in inefficient Pc silencing, ectopic expression of the corresponding gene and homeotic transformations (Bender and Fitzgerald, 2002; Hogga and Karch, 2002; Rank et al., 2002; Schmitt et al., 2005). ... See full document
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Molecular genetic analysis of the Drosophila melanogaster gene absent, small or homeotic discs1 (ash1).
... Recessive loss of function mutations in ashl cause homeotic transformations of imaginal disc derived tissue which resemble phenotypes caused by partial loss or gain of funct[r] ... See full document
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The Drosophila retained/dead ringer gene and ARID gene family function during development
... contains Drosophila RETN/DRI and mouse Bright, exhibits an extended region of similarity either side of the core ARID ...1996), Drosophila OSA/ELD (Treisman et ... See full document
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Point Mutations Within and Outside the Homeodomain Identify Sequences Required for proboscipedia Homeotic Function in Drosophila
... Class 1: pb homeotic function requires sequences both within and outside the homeodomain: Only two complete loss-of-function mutations reside in the ho- meodomain, [r] ... See full document
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Conservation of B class floral homeotic gene function between maize and Arabidopsis
... A study of the DNA-binding properties of B-class genes from Gnetum gnemon (a gymnosperm) and Lilium regale (lily, a monocot) has suggested that obligate heterodimerization of AP3-like proteins with PI-like proteins ... See full document
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