[PDF] Top 20 Function of simian virus 40 gene A in transforming infection.
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Function of simian virus 40 gene A in transforming infection.
... A A hamster embryo cell stably transformed by A58 at 33 C and then incubated in a dilute suspension of single cells for 2 weeks at 41 C without cell division; B formation of a transforme[r] ... See full document
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Role of simian virus 40 gene A function in maintenance of transformation.
... During infection of susceptible monkey cells at the restrictive temperature, group A mutants synthesize SV40 tumor T antigen and stimulate host cell DNA replication, but fail to produce [r] ... See full document
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Simian virus 40 gene A function and maintenance of transformation.
... The procedures for obtaining cells from embryos of CDF albino inbred 6:36 Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest Transformants have been isolated after infecti[r] ... See full document
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Simian virus 40 in humans
... after virus exposure to monitor for cancer development ...a transforming virus, but it is of mod- erate strength that SV40 exposure from polio vaccine is related to SV40 infection in humans ... See full document
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Distinct transformation phenotypes induced by polyoma virus and simian virus 40 in rat fibroblasts and their control by an early viral gene function.
... Thus, all polyoma virus-transformed rat cells on one side exhibited a well-characterized transformed phenotype for any property which was assayed growth characteristics on solid substrat[r] ... See full document
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Pairs of Vp1 Cysteine Residues Essential for Simian Virus 40 Infection
... During simian virus 40 (SV40) infection, the newly synthe- sized major capsid protein Vp1 forms transient intrachain and interchain disulfide linkages in the cytoplasm and is trans- ported to ... See full document
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Intracellular localization of viral polypeptides during simian virus 40 infection.
... Frequency of stained cells observed in reaction with anti- Vpl IgG Table 1, anti- Vp3 Table 2, and antiT Table 3 and of centriolar staining is plotted as a function of time after infecti[r] ... See full document
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Simian virus 40 host range/helper function mutations cause multiple defects in viral late gene expression.
... i Viral late mRNA accumulated to similar levels in Vero and BSC-1 cells infected by hrlhf mutants and wild-type SV40 but not in CV-1 cells Fig.. Even less late message was present at 32°[r] ... See full document
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A novel translational regulation function for the simian virus 40 large-T antigen gene.
... phatase function is not included in its ...complementation function localizes to a large portion of the C-terminal half of the large-T protein molecule (amino acids 401 to ...phosphatase function ... See full document
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Importance of Calcium-Binding Site 2 in Simian Virus 40 Infection
... and function in early infection ...SV40 infection. The major events leading to productive infection by a wild-type virion (Wt) in connection with calcium exchanges at site 1 and site 2 are ... See full document
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Dynein Engages and Disassembles Cytosol-Localized Simian Virus 40 To Promote Infection
... SV40 infection extends to other PyV family members, because impairing dynein function similarly disrupted human BK virus ...the virus (step ...the virus (step 3). These concerted ... See full document
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Simian Virus 40 Infection of Humans
... in infection, repressing early viral gene transcription and stimu- lating late viral gene transcription (1, 54, 98, ...its function, preventing the infected cell from un- dergoing apoptotic ... See full document
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MDM2 is a target of simian virus 40 in cellular transformation and during lytic infection.
... early gene expression leads to an altered phosphoryla- tion state of ...SV40 infection and transformation further underscores that MDM2 is a specific target of ... See full document
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Stimulation of host centriolar antigen in TC7 cells by simian virus 40: requirement for RNA and protein syntheses and an intact simian virus 40 small-t gene function.
... Frequency of centriolar antigen staining in cells infected with SV40 early viable deletion mutants, adenovirus-SV40 hybrid viruses, or adenovirus 2a % of cells showing positive centrioCe[r] ... See full document
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Simian virus 40 associates with nuclear superstructures at early times of infection.
... In CV-1 nuclei infected with radioactive SV40, more than 60% of the viral DNA was attached to the nuclear matrix at 3 h postinfection in isotonic or hypotonic buffer containing 1 mM MgCl[r] ... See full document
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Simian Virus 40-Host Cell Interaction During Lytic Infection
... It has been postulated that besides requiring the presence of T-antigen, the replication of SV40 DNA is dependent upon an event in the host cell cycle occurring in late GI or early S pha[r] ... See full document
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Temperature-Sensitive Mutants of Simian Virus 40: Infection of Permissive Cells
... Plaque characteristics of wild-type and mutant simian virus 40 SV40 stocks propagated at 32 C Virus Efficiency of plating39 C/32 C Time of plaque appearance in days d Infected cultures w[r] ... See full document
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Use of Nondefective Adenovirus-Simian Virus 40 Hybrids for Mapping the Simian Virus 40 Genome
... The order of these early SV40 antigen inducing regions in the SV40 DNA segments contained in the nondefective hybrids is: U antigen, tumor specific transplantation antigen, and T antigen[r] ... See full document
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Identification of the Simian Virus 40 Which Replicates When Simian Virus 40-Transformed Human Cells Are Fused with Simian Virus 40-Transformed Mouse Cells or Superinfected with Simian Virus 40 Deoxyribonucleic Acid
... We used mKS-U13 and mKS-BU100, ever, it was not possible to discern whether the which release large-clear plaque types of SV40h rescued SV40 was the progeny of the resident viral after f[r] ... See full document
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Selectivity of interferon action in simian virus 40-transformed cells superinfected with simian virus 40.
... These data seem to imply that a block in viral uncoating cannot be the only mechanism by Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest Experiments with SV40-transform[r] ... See full document
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