[PDF] Top 20 Genotype-Specific Complementation of Hepatitis Delta Virus RNA Replication by Hepatitis Delta Antigen
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Genotype-Specific Complementation of Hepatitis Delta Virus RNA Replication by Hepatitis Delta Antigen
... the genotype I plasmid pGDC-1 to yield pG{Peru/DC-1} (Apa); clones were checked by restriction digestion for proper ...were specific for genotype III sequences, but internal ApaI sites were added; ... See full document
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RNA-binding activity of hepatitis delta antigen involves two arginine-rich motifs and is required for hepatitis delta virus RNA replication.
... To determine whether either of the ARM-like sequences was involved in RNA binding, we made a series of deletion mutants starting from the C-terminal end of the middle domain M of HDAg am[r] ... See full document
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The Conserved Serine 177 in the Delta Antigen of Hepatitis Delta Virus Is One Putative Phosphorylation Site and Is Required for Efficient Viral RNA Replication
... HDV RNA replication, especially in the antigenomic RNA phase, we spec- ulate that the phosphorylation status of serine 177 in S-HDAg determines or strengthens the control of template specificity of ... See full document
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Hepatitis Delta Virus Antigen Is Methylated at Arginine Residues, and Methylation Regulates Subcellular Localization and RNA Replication
... Hepatitis delta virus (HDV) contains a circular RNA which encodes a single protein, hepatitis delta antigen ...an RNA-binding domain. The methylation of S-HDAg is ... See full document
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Initiation of replication of the human hepatitis delta virus genome from cloned DNA: role of delta antigen.
... DISCUSSION We have observed that transfection of both liver HuH7 and nonliver COS7 cells with a DNA trimer of the HDV genome led to an apparent replication of the HDV RNA genome.. There [r] ... See full document
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Hepatitis Delta Antigen Requires a Flexible Quasi-Double-Stranded RNA Structure To Bind and Condense Hepatitis Delta Virus RNA in a Ribonucleoprotein Complex
... epatitis delta virus (HDV) is a unique human pathogen that causes severe liver disease ...the replication and structure of the viral RNA and from the de- pendence of HDV on coinfection with ... See full document
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Initiation of Hepatitis Delta Virus Genome Replication
... to RNA processing and mRNA ...genome replication, as defined, depended not only an early source of dAg-S, as directly provided by the transfection, but also on a de novo or late source of dAg-S ...early ... See full document
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Transcription of Subgenomic mRNA of Hepatitis Delta Virus Requires a Modified Hepatitis Delta Antigen That Is Distinct from Antigenomic RNA Synthesis
... qRT-PCRs specific for HDV G-RNA, AG- RNA, and HDAg-encoding ...HDV RNA species using a previ- ously established HDV cDNA-free RNA transfection system ...dependent RNA ... See full document
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The antigen of hepatitis delta virus: examination of in vitro RNA-binding specificity.
... We found that the ability of the HDV genomic and antigenomic RNAs to fold into the rodlike structure was an essential feature for specific RNA binding, and we were able to detect a funct[r] ... See full document
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Hepatitis delta antigens enhance the ribozyme activities of hepatitis delta virus RNA in vivo.
... Hepatitis delta virus (HDV) is a satellite virus that propa- gates only in the presence of hepatitis B virus (34) and is the causative agent of acute and chronic liver diseases, ... See full document
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Effects of Conserved RNA Secondary Structures on Hepatitis Delta Virus Genotype I RNA Editing, Replication, and Virus Production
... HDV genotype I uses an editing site that is optimized for virus production rather than suitabil- ity as a substrate for ...HDV RNA replication ... See full document
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The Large Delta Antigen of Hepatitis Delta Virus Potently Inhibits Genomic but Not Antigenomic RNA Synthesis: a Mechanism Enabling Initiation of Viral Replication
... HDV RNA synthesis is thought to be a key property that allows HDAg to regulate HDV ...HDV replication in a dominant-negative inhibitory man- ner (3, 5, 9, 13, ...HDV RNA (5, ...of RNA editing, ... See full document
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Transcription of Hepatitis Delta Virus RNA by RNA Polymerase II
... the replication of the RNA genome of hepatitis delta virus (HDV) involves redirection of RNA polymerase II (Pol II), a host enzyme that normally uses DNA as a ...HDV RNA ... See full document
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Functional domains of delta antigens and viral RNA required for RNA packaging of hepatitis delta virus.
... of delta antigens (HDAgs) in the morphogenesis of hepatitis delta virus (HDV) have been studied ...surface antigen (HBsAg) of helper hepatitis B virus, whereas the ... See full document
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RNA Editing in Hepatitis Delta Virus Genotype III Requires a Branched Double-Hairpin RNA Structure
... HDV genotype III amber/W editing, site-directed mutations were constructed in a replication-competent cDNA clone of HDV genotype III, pHDV●III(⫹) ...wild-type, replication-competent construct ... See full document
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Editing on the genomic RNA of human hepatitis delta virus.
... 4693 Downloaded from http://jvi.asm.org/ on November 9, 2019 by guest It has been shown previously that during replication of the genome of human hepatitis delta virus HDV, a specific nu[r] ... See full document
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Hepatitis delta virus mutant: effect on RNA editing.
... the replication cycle of hepatitis delta virus (HDV), RNA editing occurs at position 1012 on the 1679-nucleotide RNA ...the delta antigen ( d ...HDV RNA ... See full document
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Limitations to Replication of Hepatitis Delta Virus in Avian Cells
... nome replication could be initiated in avian cells transfected with expression vectors containing wild-type HDV ...simian virus 40 late promoter, we did not detect even expression of the delta ... See full document
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Correlation of Hepatitis B Virus Surface Antigen Titer with Hepatitis Delta Virus Replication Level and Histological Activity in Chronic Hepatitis D
... HDV RNA concentration in patients with CHD was ...HDV RNA and HBsAg concentrations (p = ...HDV RNA level and serum AST ...HDV RNA concentrations and histological activity ...HDV RNA ... See full document
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RNA Replication without RNA-Dependent RNA Polymerase: Surprises from Hepatitis Delta Virus
... surface antigen as its envelope ...genomic RNA (considered a negative-strand RNA by virtue of the fact that the HDAg- coding sequence is present on the antigenomic strand) is then replicated into the ... See full document
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