[PDF] Top 20 Herpesvirus Interference with Major Histocompatibility Complex Class II-Restricted T-Cell Activation
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Herpesvirus Interference with Major Histocompatibility Complex Class II-Restricted T-Cell Activation
... infected cell, herpesviruses use general evasive approaches, such as blocking the induction of programmed cell death and shutting down host protein synthesis ...virus-specific T cells, among ... See full document
8
Kaposi's Sarcoma-Associated Herpesvirus Inhibits Expression and Function of Endothelial Cell Major Histocompatibility Complex Class II via Suppressor of Cytokine Signaling 3
... The SOCS family consists of eight structurally related proteins that attenuate signaling by blocking JAK tyrosine kinase activity or STAT activation and are typically induced by different cytokines and other ... See full document
9
The Major Histocompatibility Complex Class II Transactivator CIITA Inhibits the Persistent Activation of NF-κB by the Human T Cell Lymphotropic Virus Type 1 Tax-1 Oncoprotein
... mediated activation of NF-B by affecting the phosphorylation of FIG 2 Inhibition of Tax-1-dependent NF- B activation requires the N-terminal region of ...the activation by Tax-1, which is set to ... See full document
14
Novel and frequent mutations of hepatitis B virus coincide with a major histocompatibility complex class I-restricted T-cell epitope of the surface antigen.
... within major histocompatibility complex (MHC) class I-re- stricted cytotoxic T-cell epitopes ...MHC class II-, instead of class I-, restricted ... See full document
5
Immunogenic peptides of influenza virus subtype N1 neuraminidase identify a T-cell determinant used in class II major histocompatibility complex-restricted responses to infectious virus.
... To test whether immunization with intact virus could stimulate T cells specific for peptides, BALB/c mice were injected intraperitoneally with PR8 virus, either infectious or UV inactiva[r] ... See full document
5
Substitutions in a Major Histocompatibility Complex Class II-Restricted Human Immunodeficiency Virus Type 1 gp120 Epitope Can Affect CD4+ T-Helper-Cell Function
... MHC class II molecules have been determined through the charac- terization of naturally processed peptides eluted from purified MHC class II ...MHC class II- associated ... See full document
5
Identification of Major Histocompatibility Complex Class II-Restricted Antigens and Epitopes of the Epstein-Barr Virus by a Novel Bacterial Expression Cloning Approach
... identify T-helper-cell epitopes within known antigens by picking and analyzing single green bac- terial colonies ...viral T H -cell antigens and applied this method to ... See full document
8
Theiler's virus persistence and demyelination in major histocompatibility complex class II-deficient mice.
... a class I- or class II-restricted T cell-mediated ...Oligodendroglial cell virus persistence and damage to the inner glial loop are observed chronically in Ab o ... See full document
9
Major Histocompatibility Complex Class II HLA-DRα Is Downregulated by Kaposi's Sarcoma-Associated Herpesvirus-Encoded Lytic Transactivator RTA and MARCH8
... the cell lysates were harvested at the indi- cated ...KSHV-positive cell line, so RTA expression in this cell line will result in KSHV lytic ... See full document
12
Role of CD4 molecule in the induction of interleukin 2 and interleukin 2 receptor in class II major histocompatibility complex restricted antigen specific T helper clones T cell receptor/CD3 complex transmits CD4 dependent and CD4 independent signals
... antigen-induced activation of T helper (Th) cells, but its contribution to signal transduction events resulting in physiologic T cell function is ill ...in class II ... See full document
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Kaposi's Sarcoma-Associated Herpesvirus Viral Interferon Regulatory Factor 3 Inhibits Gamma Interferon and Major Histocompatibility Complex Class II Expression
... MHC II regulation by vIRF-3 is mediated by regulation of CIITA. MHC II expression is regulated by one master switch protein, the class II transactivator ...three cell-type-specific ... See full document
8
The Lytic Cycle of Epstein-Barr Virus Is Associated with Decreased Expression of Cell Surface Major Histocompatibility Complex Class I and Class II Molecules
... expressing cell surface ...MHC class I expression in the lytic cycle? Recently, Dreyfus et ...human T cells. Since activation of NF- B is a major signaling function of LMP1, we ... See full document
10
Host response to Sendai virus in mice lacking class II major histocompatibility complex glycoproteins.
... that class II MHC-restricted CD4 1 Th cells are necessary to promote the virus-specific antibody ...1 T-cell response to a herpesvirus ...of class II ... See full document
6
Major histocompatibility complex class I-restricted cytotoxic T-lymphocyte responses in horses infected with equine herpesvirus 1.
... Lysys II software; Becton Dickinson, San Jose, ...equine T-lymphocyte subset markers, indicated that both CD4 1 and CD8 1 lymphocytes became infected with EHV-1 and expressed viral ... See full document
7
Generation of Antiviral Major Histocompatibility Complex Class I-Restricted T Cells in the Absence of CD8 Coreceptors
... CD4 T-cell-dependent and -independent antiviral hu- moral responses, which, while promoting viral clearance, are not sufficient to prevent PyV tumorigenesis (1, 13, 27, 37, ...CD8 T-cell ... See full document
9
Immunodominance of major histocompatibility complex class I-restricted influenza virus epitopes can be influenced by the T-cell receptor repertoire.
... of class II-restricted epitopes has also been ...peripheral T cells to l phage repressor (cI) ...transgenic T cells could respond to either epi- tope following immunization with the ... See full document
7
Investigating and Manipulating Major Histocompatibility Complex (MHC) Class I-Restricted Peptide Epitopes and Cognate T-cell Responses.
... autoreactive T cells in these patients somehow ...CD8+ T cells (Bulek et ...of T cells displaying more than one rearranged TCR gene product at the cell membrane is also a possibility (Simpson ... See full document
192
Analysis of murine major histocompatibility complex class II-restricted T-cell responses to the flavivirus Kunjin by using vaccinia virus expression.
... When recombinant vaccinia virus-derived Kunjin virus antigen preparations were tested in vitro, Kunjin virus-immune T cells of H-2b haplotype responded most strongly to structural prM, C[r] ... See full document
10
Functional Macroautophagy Induction by Influenza A Virus without a Contribution to Major Histocompatibility Complex Class II-Restricted Presentation
... MHC class II-re- stricted presentation of individual antigens (16, 35, 44, 45, 50, 60), our goal was to determine the role in the CD4 ⫹ T cell response to a complex pathogen, ... See full document
11
Roles of Major Histocompatibility Complex Class II in Inducing Protective Immune Responses to Influenza Vaccination
... fluorescence-activated cell sorting (FACS) to check phe- notypes of MHC-II KO and B6 WT ...to cell phe- notypes, MHC-II–FITC ...plot. Cell acquisition was performed with a multilaser ... See full document
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