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Identification of key genes and pathways using bioinformatics analysis in septic shock children
... the septic shock and normal children was obtained from Affymetrix GPL570 platform (Affymetrix Human Genome U133 Plus ...in septic shock ...the septic shock and normal ... See full document
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<p>Identification of key genes, pathways and miRNA/mRNA regulatory networks of CUMS-induced depression in nucleus accumbens by integrated bioinformatics analysis</p>
... In brief, if there were depression-like behaviors 24 hours after treatment (CUMS), both control and CUMS mice were anesthetized by using isoflurane and decapitated by guillotine. NAc samples were dissected and ... See full document
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<p>Identification of key genes and pathways in seminoma by bioinformatics analysis</p>
... harmful substances. However, it is dif fi cult to maintain a normal structure and function in cancer tissue. Moreover, studies have suggested that the loss of cell cycle regulation leads to genomic instability, and the ... See full document
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Original Article The identification of the key genes and pathways in septic shock using an integrated bioinformatics analysis
... of septic shock ...inflammatory pathways and how they inter- act with each other during sepsis are still ...data using bioinformatics meth- ...network analysis, and the ... See full document
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<p>Identification of key pathways and hub genes in basal-like breast cancer using bioinformatics analysis</p>
... hub genes, and core pathways between BC (comparing the basal subtype and the non basal subtype) and matched normal controls were identified by the bioinformatics ...plotter analysis, gene ... See full document
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Identification of differentially expressed genes and signaling pathways in ovarian cancer by integrated bioinformatics analysis
... 99 genes were upregulated and 91 genes were downregulated. Using R software, we identi- fied the top 20 most significantly up- and downregulated genes that could be the most related to the ... See full document
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Original Article Identification of key genes in preeclampsia-associated trophoblast cells using bioinformatics analysis
... In addition, ADCY3 is a membrane-associated protein involved in catalyzing the formation of cyclic adenosine-3’,5’-monophosphate (cAMP). Recent studies have revealed that overexpres- sion of ADCY3 stimulates HEK293 cell ... See full document
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Original Article Identification of key genes associated with idiopathic pulmonary fibrosis using bioinformatics analysis
... expressed genes (DEGs) between IPF and control ...module analysis for PPI net- work was performed using BioNet ...down-regulated genes were ...enrichment analysis indicated that PDGFRA ... See full document
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<p>Identification of Chemoresistance-Associated Key Genes and Pathways in High-Grade Serous Ovarian Cancer by Bioinformatics Analyses</p>
... needed. Bioinformatics analysis is an effective and practical method to predict key genes and pathways in tumorigenesis or other pathological ...expressed genes (DEGs) were ... See full document
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<p>Identification of key genes and pathways in Ewing’s sarcoma patients associated with metastasis and poor prognosis</p>
... transcribed genes were located in euchromatin, which tended to cluster to the center of the ...related pathways would conduce to thoroughly over- come this ...Additionally, bioinformatics ... See full document
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Identification of hub genes with prognostic values in gastric cancer by bioinformatics analysis
... different pathways, biological process, mo- lecular ...network analysis, combined with survival analysis and mRNA-miRNA interaction analysis, also constructed gene – transcription factor ... See full document
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Identification and interaction analysis of key genes and microRNAs in hepatocellular carcinoma by bioinformatics analysis
... By using parallel measurement, a change in CDKN1B, CDKN1C, paralemmin-2, and CXCL12 levels was suggested as consistent with in- creased miR-221 activity in the same ...naling pathways, are reported playing ... See full document
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Identification of key pathways and genes with aberrant methylation in prostate cancer using bioinformatics analysis
... with positions of TSS of the identified hub DMGs were also retrieved using PEpID (a prostate epigenetic database in mammals; Table S4). Once the CpG islands and the methy- lated cytosines positions were retrieved, ... See full document
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Identification of key pathways and genes in <em>TP53 </em>mutation acute myeloid leukemia: evidence from bioinformatics analysis
... hub genes of DEGs, protein–protein interactomes were constructed using STRING (Figure ...ten genes ranked by degree were iden- tified as hub ...hub genes included CDH1, also known as ... See full document
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Identification of molecular target genes and key pathways in hepatocellular carcinoma by bioinformatics analysis
... combining bioinformatics analysis has allowed the comprehensive identification of hundreds of differentially expressed genes (DEGs) involved in the development and progression of HCC, due to ... See full document
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Original Article Identification of candidate genes and pathways in cisplatin-resistant NSCLC by integrated bioinformatics analysis
... constructed using NetworkAnalyst (http:// ...module analysis was then per- formed to determine the key modules and hub ...vival analysis of hub ... See full document
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The Influence of Developmental Age on the Early Transcriptomic Response of Children with Septic Shock
... Septic shock is a frequent and costly problem among patients in the pediatric intensive care unit (PICU) and is associated with high mortality and devastating survivor ...from children with ... See full document
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Identification of key pathways and genes influencing prognosis in bladder urothelial carcinoma
... of bioinformatics analysis of potential prognosis- related DEGs, we identified biomarkers that are related to the prognosis of ...prognosis-related genes and pathways for future ...comparative ... See full document
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Original Article Identification of key pathways and candidate genes in gliomas by bioinformatics analysis
... a bioinformatics analysis to identify diagnostic biomark- ers and reveal potential therapeutic targets for ...KEGG analysis revealed that 244 DEGs were mainly enriched in 11 terms and 10 ...hub ... See full document
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Original Article Identifying key genes in rheumatoid arthritis using bioinformatics analysis
... Hsp70 genes, such as the HSPA8 gene, might contrib- ute to the development of ...a bioinformatics analysis that has not been confirmed by appro- priate ... See full document
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