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[PDF] Top 20 Identification of novel long non-coding RNAs deregulated in hepatocellular carcinoma using RNA-sequencing

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Identification of novel long non-coding RNAs deregulated in hepatocellular carcinoma using RNA-sequencing

Identification of novel long non-coding RNAs deregulated in hepatocellular carcinoma using RNA-sequencing

... HBV-associated HCCs, while our series contained mostly patients with HCV- or alcohol-associated HCCs. Thus, differences in patient population, technology used and the limited number of samples may explain the different ... See full document

16

Original Article Prognostic significance of long non-coding RNA PCAT-1 expression in human hepatocellular carcinoma

Original Article Prognostic significance of long non-coding RNA PCAT-1 expression in human hepatocellular carcinoma

... Background: Long non-coding RNAs (lncRNAs) play widespread roles in gene regulation and cellular pro- ...in hepatocellular carcinoma (HCC) are not yet well ...adjacent ... See full document

6

Up-regulation of CTD-2547G23.4 in hepatocellular carcinoma tissues and its prospective molecular regulatory mechanism: a novel qRT-PCR and bioinformatics analysis study

Up-regulation of CTD-2547G23.4 in hepatocellular carcinoma tissues and its prospective molecular regulatory mechanism: a novel qRT-PCR and bioinformatics analysis study

... noncoding RNAs (lncRNAs) are transcriptional RNA molecules with little protein-coding capacity that are longer than 200 nucleotides ...screening novel lncRNAs which could be excellent ... See full document

17

Identification of novel long non-coding RNAs in triple-negative breast cancer

Identification of novel long non-coding RNAs in triple-negative breast cancer

... prognosis. Long non-coding RNAs (lncRNAs) are subclass of noncoding RNAs that have been recently shown to play critical roles in cancer ... See full document

10

Circulation long non-coding RNAs act as biomarkers for predicting tumorigenesis and metastasis in hepatocellular carcinoma

Circulation long non-coding RNAs act as biomarkers for predicting tumorigenesis and metastasis in hepatocellular carcinoma

... 20 non-metastasis HCC patients as the training set, another 79/78 patients as validation ...a novel predictor for the metastasis of HCC (Figure 2B, ... See full document

11

Identification and Functional Characterization of Long Non-coding RNA MIR22HG as a Tumor Suppressor for Hepatocellular Carcinoma

Identification and Functional Characterization of Long Non-coding RNA MIR22HG as a Tumor Suppressor for Hepatocellular Carcinoma

... Long non-coding RNAs (lncRNAs) critically participate in various physiological processes, with their dysregulation associated with multiple human diseases, including cancers ...adjacent ... See full document

15

Original Article Overexpression of long non-coding RNAs DUXAP9 and DUXAP10 is associated with prognosis in patients with hepatocellular carcinoma after hepatectomy

Original Article Overexpression of long non-coding RNAs DUXAP9 and DUXAP10 is associated with prognosis in patients with hepatocellular carcinoma after hepatectomy

... LncRNAs have been found dysregulated in many diseases, especially neoplastic disease [24, 25]. Accumulating studies have demon- strated that lncRNAs can be used as tumor bio- markers for prognosis [26, 27]. In present ... See full document

8

Original Article Up-regulation of long non-coding RNA Sox2ot promotes hepatocellular carcinoma cell metastasis and correlates with poor prognosis

Original Article Up-regulation of long non-coding RNA Sox2ot promotes hepatocellular carcinoma cell metastasis and correlates with poor prognosis

... Background: Long non-coding RNAs (lncRNAs) have been shown to have important regulatory roles in can- cer biology, and the lncRNA Sox2ot is up-regulated in some ...cellular carcinoma ... See full document

7

Identification of long non-coding RNA-related and –coexpressed mRNA biomarkers for hepatocellular carcinoma

Identification of long non-coding RNA-related and –coexpressed mRNA biomarkers for hepatocellular carcinoma

... noncoding RNAs (lncRNAs) are a class of non- coding RNA transcripts longer than 200 nucleotides that were previously believed to represent transcriptional ...Antisense RNA 1 (ZFAS1) ... See full document

10

Identification of novel long non-coding RNAs in clear cell renal cell carcinoma

Identification of novel long non-coding RNAs in clear cell renal cell carcinoma

... performed using quantitative real-time PCR in 55 ccRCC and 52 normal renal ...validated using PCR: lnc-BMP2-2 (mean expression change: 37-fold), lnc-CPN2-1 (13-fold), lnc-FZD1-2 (9-fold), lnc-ITPR2-3 ... See full document

10

Hepatitis B virus x protein induces epithelial mesenchymal transition of hepatocellular carcinoma cells by regulating long non coding RNA

Hepatitis B virus x protein induces epithelial mesenchymal transition of hepatocellular carcinoma cells by regulating long non coding RNA

... induce EMT in HCC. In 2006, Lee et al. first proved the effect of HBx on EMT. Their study found that HBx activated STAT5b, which further promoted cancer cell motility and invasiveness by inducing EMT [10]. Succes- ... See full document

9

Identification of functional long non-coding RNAs in C. elegans

Identification of functional long non-coding RNAs in C. elegans

... Growth curves were estimated using long-term video imaging. In short, a custom camera system was used to record backlit images of C. elegans from the ex utero egg stage to the egg-laying adult stage (~ 65 ... See full document

14

Original Article Increased expression of long non-coding RNA TUG1 associates with poor prognosis of hepatocellular carcinoma

Original Article Increased expression of long non-coding RNA TUG1 associates with poor prognosis of hepatocellular carcinoma

... performed using the software of SPSS version ...adjacent non-cancerous ...ated using the Chi-square test and Fisher’s exact test, as ...performed using the Kaplan-Meier me- thod, and ... See full document

6

The prognostic value of lncRNA SNHG6 in cancer patients

The prognostic value of lncRNA SNHG6 in cancer patients

... as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were ... See full document

8

Original Article Clinical implication of long non-coding RNA NEAT1 expression in hepatocellular carcinoma patients

Original Article Clinical implication of long non-coding RNA NEAT1 expression in hepatocellular carcinoma patients

... several long non-coding RNAs (lncRNAs) and metastasis, drug resistance and other clinical outcome in several types of can- cers ...antisense RNA (HOTAIR), metastasis associated lung ... See full document

8

Long non-coding RNA TPTEP1 inhibits hepatocellular carcinoma progression by suppressing STAT3 phosphorylation

Long non-coding RNA TPTEP1 inhibits hepatocellular carcinoma progression by suppressing STAT3 phosphorylation

... Long non-coding RNAs (LncRNAs) are more than 200 nucleotides long with little or no protein-coding capacity [5]. LncRNAs have been identified to play critical roles in various ... See full document

15

Protocol: a beginner’s guide to the analysis of RNA-directed DNA methylation in plants

Protocol: a beginner’s guide to the analysis of RNA-directed DNA methylation in plants

... By using the model organism Arabidopsis thaliana, we developed an easy-to-follow, integrative procedure for time-efficient, quantitative measurement of DNA methylation, small interfering RNAs, and scaffold ... See full document

9

Prognostic significance of the long noncoding RNAs in nasopharyngeal carcinoma: a systematic review and meta-analysis

Prognostic significance of the long noncoding RNAs in nasopharyngeal carcinoma: a systematic review and meta-analysis

... Three of us (HuanHuan Guo, Shuo Huang, and Shuang Li) extracted the provided data including author, publication year, lncRNAs and their biotypes, methods, case number, outcomes, cut-off value, and follow-up months. The ... See full document

17

Original Article Long non-coding RNA CASC2 reduces sorafenib resistance in hepatocellular carcinoma cells via inhibition of miR-21-mediated PI3K/AKT pathways

Original Article Long non-coding RNA CASC2 reduces sorafenib resistance in hepatocellular carcinoma cells via inhibition of miR-21-mediated PI3K/AKT pathways

... To further clarify molecular mechanisms regarding the impact of CASC2 on sorafenib- resistant HCC, an online database (www.micro- RNA.org) was used to predict potential targets of CASC2. A potential miR-21 binding site ... See full document

9

Identification of a novel long non-coding RNA within RUNX1 intron 5

Identification of a novel long non-coding RNA within RUNX1 intron 5

... 5 using two ...prediction, using the online tool YAPP Eukaryotic Core Promoter ...types using Hidden Markov Models (HMM) based on raw CAGE data, that is, data from actually expressed RNAs, ... See full document

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