[PDF] Top 20 Human immunodeficiency virus type 1 gp120 envelope glycoprotein regions important for association with the gp41 transmembrane glycoprotein.
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Human immunodeficiency virus type 1 gp120 envelope glycoprotein regions important for association with the gp41 transmembrane glycoprotein.
... To compare the ability of different gpl20 mutants to associate with the gp4l transmembrane glycoprotein, the levels of envelope glycoproteins in the lysates and supernatants of the trans[r] ... See full document
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Peptides Corresponding to the Heptad Repeat Motifs in the Transmembrane Protein (gp41) of Human Immunodeficiency Virus Type 1 Elicit Antibodies to Receptor-Activated Conformations of the Envelope Glycoprotein
... The envelope glycoprotein (Env) of the human immunode- ficiency virus type 1 (HIV-1) mediates virus entry by fusing viral and cellular membranes, resulting in ... See full document
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Structural and Functional Analysis of Interhelical Interactions in the Human Immunodeficiency Virus Type 1 gp41 Envelope Glycoprotein by Alanine-Scanning Mutagenesis
... by human immunodeficiency virus type 1 (HIV-1) is promoted by the refolding of the viral envelope glycoprotein into a fusion-active ...the gp41 ectodomain ... See full document
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Regulation of Human Immunodeficiency Virus Type 1 Envelope Glycoprotein Fusion by a Membrane-Interactive Domain in the gp41 Cytoplasmic Tail
... for 1 h at room ...vaccinia virus vTF7-3 expressing T7 polymerase and transfected with pSP73 expressing Envs as described ...with 1 g/ml of the FITC- conjugated anti-gp120 monoclonal ...with ... See full document
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Evaluation of the contribution of the transmembrane region to the ectodomain conformation of the human immunodeficiency virus (HIV 1) envelope glycoprotein
... of gp120 and gp41 changes, or selected by the binding of specific antibodies ...the gp41 membrane-spanning region and MPER are disordered, leaving open the possibility that the interaction with the ... See full document
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Variable-Loop-Deleted Variants of the Human Immunodeficiency Virus Type 1 Envelope Glycoprotein Can Be Stabilized by an Intermolecular Disulfide Bond between the gp120 and gp41 Subunits
... the gp120 N-linked glycans, but we have found that other glycosylation sites in the C3 and V4 regions can be eliminated from the ⌬V1V2* SOS gp140 protein without affecting its overall ...the gp120 ... See full document
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Reevaluation of Amino Acid Variability of the Human Immunodeficiency Virus Type 1 gp120 Envelope Glycoprotein and Prediction of New Discontinuous Epitopes
... evidence and the effect on cell tropism explain the adaptive significance of amino acid changes in the V3 loop that is exposed to the solvent. The PS sites in the V1/V2 loop (130 Lys, 132 Thr, 172 Glu, and 178 Lys) and ... See full document
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Analysis of the interaction of the human immunodeficiency virus type 1 gp120 envelope glycoprotein with the gp41 transmembrane glycoprotein.
... an envelope glycopro- tein that is unable to be processed proteolytically at the gp120/gp41 ...the envelope gene ...of envelope glycoproteins were performed as described ... See full document
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Stoichiometry of Envelope Glycoprotein Trimers in the Entry of Human Immunodeficiency Virus Type 1
... ⫽ 1 entry stoichiometry utilize protein receptors ...A virus, in which the binding of the HA1 glycoprotein to cell surface sialic acid serves mostly to attach the virus and allow targeting to ... See full document
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Determinants of human immunodeficiency virus type 1 envelope glycoprotein oligomeric structure.
... influenza virus hemagglutinin transmembrane protein HA2 ...the gp41 putative amphi- pathic a -helix may make analogous interactions in twofold or fourfold symmetry to stabilize the gp41 ...of ... See full document
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A Conformation-Specific Monoclonal Antibody Reacting with Fusion-Active gp41 from the Human Immunodeficiency Virus Type 1 Envelope Glycoprotein
... the gp41 ectodomain generated a trimeric, a-helical complex composed of two peptides, designated N-51 and C-43, that are derived from the N- and C-terminal heptad repeat regions, respectively ...within ... See full document
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Characterization of the Outer Domain of the gp120 Glycoprotein from Human Immunodeficiency Virus Type 1
... The envelope glycoprotein of human immunodeficiency vi- rus 1 (HIV-1) is expressed as a gp160 precursor, which is then proteolytically cleaved into two mature glycoproteins, ... See full document
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Membrane permeabilization by different regions of the human immunodeficiency virus type 1 transmembrane glycoprotein gp41.
... the gp41 protein or the particular gp41 fragments at several postinduction times is shown in ...thesize gp41, fragment A, or fragment E behave similarly to control cells with respect to PI entry; ... See full document
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Stabilization of Human Immunodeficiency Virus Type 1 Envelope Glycoprotein Trimers by Disulfide Bonds Introduced into the gp41 Glycoprotein Ectodomain
... V3 gp120 loops and a large portion of the gp41 cytoplasmic ...the gp41 cytoplas- mic tail was truncated after residue 713 by the introduction of a stop codon into the env ...HIV-1 ... See full document
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Association of human immunodeficiency virus type 1 envelope glycoprotein with particles depends on interactions between the third variable and conserved regions of gp120.
... HIV-1 virions present in supernatants from metabolically labeled HeLa cells transfected with the wild-type pNL4-3 or the Q-267, Q-267/I-308, or 1-308 mutant proviral DNA were pelleted by[r] ... See full document
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Changes in the transmembrane region of the human immunodeficiency virus type 1 gp41 envelope glycoprotein affect membrane fusion.
... The presence of wild-type levels of gpl20 glycoprotein in the supernatants of COS-1 cells transfected with the plasmids expressing the mutant envelope glycoproteins suggested that these [r] ... See full document
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gp120-independent fusion mediated by the human immunodeficiency virus type 1 gp41 envelope glycoprotein: a reassessment.
... 1977 Downloaded from http://jvi.asm.org/ on November 9, 2019 by guest In a natural context, membrane fusion mediated by the human immunodeficiency virus type 1 HIV-1 envelope glycoprotei[r] ... See full document
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Antibody cross-competition analysis of the human immunodeficiency virus type 1 gp120 exterior envelope glycoprotein.
... between gp120 domains have also been ...C4 regions of gp120 (31, ...of gp120, of a large segment of the C1 domain from approximately residues 80 to ...the gp41-associative ...of ... See full document
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Reevaluation of the Requirement for TIP47 in Human Immunodeficiency Virus Type 1 Envelope Glycoprotein Incorporation
... or virus release efficiency ...a gp41 CT truncation mutant (NL4-3/CTdel-144) in Jurkat cells by ap- plying the same VSV-G pseudotyping approach as the one used for TIP47-depleted Jurkat ...and virus ... See full document
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Envelope Glycoprotein Incorporation, Not Shedding of Surface Envelope Glycoprotein (gp120/SU), Is the Primary Determinant of SU Content of Purified Human Immunodeficiency Virus Type 1 and Simian Immunodeficiency Virus
... Human immunodeficiency virus type 1 (HIV-1) and simian immunodeficiency virus (SIV) particles typically contain small amounts of the surface envelope protein ... See full document
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