[PDF] Top 20 Isolation and Characterization of Replication-Competent Human Immunodeficiency Virus Type 1 from a Subset of Elite Suppressors
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Isolation and Characterization of Replication-Competent Human Immunodeficiency Virus Type 1 from a Subset of Elite Suppressors
... isolates from four ...the replication capacity of the ...obtained from multiple ES. We were not able to isolate virus from all of the ES ...ES from whom replication ... See full document
11
Evidence of CD8+ T-Cell-Mediated Selective Pressure on Human Immunodeficiency Virus Type 1 nef in HLA-B*57+ Elite Suppressors
... ES from whom we obtained plasma ...amplified from both resting CD4 ⫹ T cells and ...amplified from the subject who transmitted HIV-1 to her ...two replication-competent isolates ... See full document
10
Role of Natural Killer Cells in a Cohort of Elite Suppressors: Low Frequency of the Protective KIR3DS1 Allele and Limited Inhibition of Human Immunodeficiency Virus Type 1 Replication In Vitro
... lymphoblasts from ES and uninfected patients with the reference HIV-1 isolate Ba-L, and then we incubated these cells with autologous, un- stimulated CD8 ⫹ T cells, NK cells, or NK cells in the presence of ... See full document
7
Neutralizing Antibodies Do Not Mediate Suppression of Human Immunodeficiency Virus Type 1 in Elite Suppressors or Selection of Plasma Virus Variants in Patients on Highly Active Antiretroviral Therapy
... including elite suppressors (ES) and patients on effective highly active antiretroviral therapy ...distinct subset of long-term nonprogressors (LTNPs) who maintain stable CD4 ⫹ T-cell counts and ... See full document
13
Isolation and Molecular Characterization of a Nelfinavir (NFV)-Resistant Human Immunodeficiency Virus Type 1 That Exhibits NFV-Dependent Enhancement of Replication
... extracted from HIV-1 isolates with a High-Pure viral RNA kit (Boehringer, Mannheim, Germany), followed by RT-PCR with a One-Step RNA PCR kit (TaKaRa Shuzo, Otsu, Japan) to amplify the HIV-1 gag-pol ... See full document
10
HLA-Associated Alterations in Replication Capacity of Chimeric NL4-3 Viruses Carrying gag-protease from Elite Controllers of Human Immunodeficiency Virus Type 1
... RNA isolation and nested RT-PCR amplification of gag-protease from ...products from plasma containing the entire gag and protease genes were obtained in the context of a previous study (36), and ... See full document
10
Transmission of Human Immunodeficiency Virus Type 1 from a Patient Who Developed AIDS to an Elite Suppressor
... unique subset of human immu- nodeficiency virus type 1 (HIV-1)-infected individuals called elite suppressors (ES) control viral replication remain largely ... See full document
16
Effective Downregulation of HLA-A*2 and HLA-B*57 by Primary Human Immunodeficiency Virus Type 1 Isolates Cultured from Elite Suppressors
... are human immunode- ficiency virus type 1 (HIV-1)-infected individuals who maintain normal CD4 ⫹ T-cell counts and remain asymptomatic for longer than 10 years without therapy ...as ... See full document
6
Role of APOBEC3G/F-Mediated Hypermutation in the Control of Human Immunodeficiency Virus Type 1 in Elite Suppressors
... HAART from our ...free virus in the plasma that can be detected with extremely sensitive RT- PCR ...amplified from the patient’s ...pressure from CD8 ⫹ T cells ... See full document
6
Molecular characterization of human immunodeficiency virus type 1 cloned directly from uncultured human brain tissue: identification of replication-competent and -defective viral genomes.
... 8 3973-3985 Copyright © 1991, American Society for Microbiology Molecular Characterization of Human Immunodeficiency Virus Type 1 Cloned Directly from Uncultured Human Brain Tissue: Iden[r] ... See full document
13
Characterization of human immunodeficiency virus type 1 Vif particle incorporation.
... a 1:1,000 dilution of rabbit anti-Vif antiserum (obtained from Dana Gabuzda through the AIDS Research and Reference Reagent Program, Division of AIDS, National Institute of Allergy and Infectious Diseases) ... See full document
6
TAR-independent replication of human immunodeficiency virus type 1 in glial cells.
... As astrocytic glial cells supported TAR-independent gene expression from an HIV-1 LTR in subgenomic reporter constructs, we evaluated whether unstimulated astrocytic glial cells could su[r] ... See full document
7
Identification of a replication-competent pathogenic human immunodeficiency virus type 1 with a duplication in the TCF-1alpha region but lacking NF-kappaB binding sites.
... The human immunodeficiency virus type 1 (HIV-1) provi- rus, like all retroviruses, contains two identical long terminal repeats (LTRs) flanking the three structural genes gag, ... See full document
6
Requirement of human immunodeficiency virus type 1 nef for in vivo replication and pathogenicity.
... No depletion of CD4+ human thymocytes was observed in implants infected with either HIV-lJRCSF or its nef mutant at 3 or 6 weeks postinfection compared with controls consisting of mock-i[r] ... See full document
8
Susceptibility of Rat-Derived Cells to Replication by Human Immunodeficiency Virus Type 1
... HIV-1 replication cycle was also studied using pseudotyped viruses as described ...isolated from neonatal rat brains and enriched by subcultivation (see Materials and Meth- ods), and the purity of ... See full document
11
Dynamics of Human Immunodeficiency Virus Type 1 Replication in Vertically Infected Infants
... Little information regarding the kinetics of HIV-1 replica- tion in vertically infected infants and children is available. We therefore undertook a study in which potent antiretroviral therapies were used to probe ... See full document
6
Few infected CD4+ T cells but a high proportion of replication-competent provirus copies in asymptomatic human immunodeficiency virus type 1 infection.
... 4 0022-538X/91/042019-05$02.00/0 Copyright © 1991, American Society for Microbiology Few Infected CD4+ T Cells but a High Proportion of ReplicationCompetent Provirus Copies in Asymptomat[r] ... See full document
5
Characterization of a Late Entry Event in the Replication Cycle of Human Immunodeficiency Virus Type 2
... result from infection of a small proliferating population (30, 31, 49), although these results are controversial ...leukemia virus (MLV) is produced in the presence of high concentra- tions of dNTPs, then ... See full document
9
Multiple Blocks to Human Immunodeficiency Virus Type 1 Replication in Rodent Cells
... of human gene products that are required for early steps in the human immuno- deficiency virus type 1 (HIV-1) life cycle has raised the possibility that rodents might be ... See full document
10
Rab9 GTPase Is Required for Replication of Human Immunodeficiency Virus Type 1, Filoviruses, and Measles Virus
... HIV replication depends on the expres- sion of the Rab9 effector p40, PIKfyve (which promotes p40 membrane attachment), and Rab11A ...Marburg virus) was included as a negative control, as targeting this ... See full document
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